Research Associate - Jiang Lab
- Employer
- University of Virginia
- Location
- Charlottesville, Virginia, United States of America
View more categoriesView less categories
- Employment Type
- Full Time
- Institution Type
- Four-Year Institution
Job Details
Are you passionate about unraveling the mysteries of the human brain? Do you have a strong desire to contribute to groundbreaking discoveries in the field of neurodegenerative diseases? Look no further! The Lulu Jiang Lab at the University of Virginia (UVA) is seeking a talented individual to join our dynamic research team as a Postdoctoral Research Associate.
The Lulu Jiang Lab is dedicated to advancing our understanding of the intricate workings of the brain. At our lab, we have a strong emphasis on comprehending the pathophysiology of neurodegenerative diseases, such as Alzheimer's disease (AD), Parkinson's disease (PD), and other related dementia disorders. Our primary objective is to deepen our understanding of these disease conditions. To achieve this, we employ cutting-edge technologies in disease modeling, allowing us to recreate and study the pathological processes in a controlled environment. By utilizing these advanced techniques, we gain insights into the intricate molecular mechanisms that underlie the progression of these diseases. Moreover, our lab is dedicated to the development of innovative therapeutic strategies. We strive to translate our research findings into practical applications that could potentially lead to the discovery of novel treatments. By integrating our knowledge of disease mechanisms with targeted therapeutic approaches, we aim to make significant contributions to the field of neurodegenerative disease research. Overall, our lab is committed to advancing the understanding, diagnosis, and treatment of neurodegenerative diseases through the utilization of state-of-the-art technologies and the exploration of molecular mechanisms.
Our research focuses on several key areas that drive our scientific interests and contribute to the understanding and treatment of neurodegenerative diseases.
These areas include:
Investigation of RNA modifications and epitranscriptomic mechanisms in the pathogenesis of Alzheimer's disease (AD) and related dementias. By studying how RNA modifications impact disease progression, we aim to uncover novel therapeutic targets and diagnostic markers.
Exploration of neuron-glia interactions and neuroimmunological mechanisms underlying the progression of AD and Parkinson's disease (PD). Understanding the complex interplay between neurons and glial cells will provide crucial insights into the underlying mechanisms and potential avenues for therapeutic intervention.
Utilization of iPSC-induced 3D human brain organoid models to study neurodegenerative diseases and enable precision medicine approaches. These advanced models allow us to recapitulate the complexity of the human brain, facilitating the identification of disease mechanisms and the development of personalized treatment strategies.
Elucidation of the molecular mechanisms driving prion-like propagation in the Braak stages of AD. Investigating the spread of pathological proteins in the brain will contribute to our understanding of disease progression and may lead to the development of interventions that disrupt this process.
Development of innovative genetic and small molecule therapeutics for neurodegenerative diseases. Our research aims to identify and optimize potential therapeutic targets, including genetic approaches and small molecules, with the goal of ultimately translating these findings into effective treatments for patients.
These research directions represent our current focus and ongoing projects, which collectively contribute to the advancement of knowledge and the development of new strategies for the management and treatment of neurodegenerative diseases.
With state-of-the-art facilities and a collaborative environment, we strive to foster creativity, innovation, and scientific excellence.
Responsibilities
Conducting experiments and data analysis related to ongoing research projects.
Contributing to the development and implementation of research protocols.
Collaborating with fellow researchers and scientists within and outside the lab.
Presenting research findings at conferences and publishing in scientific journals.
Assisting in the training and mentorship of junior lab members.
Minimum Qualifications
Education: Doctoral degree
Physical Demands
This is primarily a sedentary job involving extensive use of desktop computers. The job does occasionally require traveling some distance to attend meetings, and programs.
Salary Range
Salary will be commensurate with education and experience.
Position Type & Work Location
This is an exempt-level, benefited position. Learn more about UVA benefits.
This is a restricted position, which is dependent on funding and is contingent upon funding availability.
This position is based in Charlottesville, VA, and must be performed fully on-site.
About UVA and the Community
To learn more about UVA and in the Charlottesville area, visit UVA Life and Embark CVA.
Application Timeline
Application review will begin after August 15, 2026.
Additional Requirements
Background checks and pre-employment health screenings will be conducted on all new hires prior to employment.
How to Apply
Please apply online, by searching for requisition number R0086042.
Internal applicants may search and apply for jobs on the UVA Internal Careers website.
Complete an application with the following documents:
Resume
Cover Letter
Upload all materials into the resume submission field. You can submit multiple documents into this one field or combine them into one PDF. Applications without all required documents will not receive full consideration.
Reference Check Process
Reference checks will be completed by UVA’s third-party partner, SkillSurvey, during the final phase of the interview. Five references will be requested, with at least three responses required.
Contact
For more information about our department and our lab, please visit https://med.virginia.edu/neuroscience/ or contact Lulu Jiang at wpm5vs@virginia.edu.
For questions about the application process, please contact Jon Freeman, jf2sw@virginia.edu.
The University of Virginia is an equal opportunity employer. All interested persons are encouraged to apply, including veterans and individuals with disabilities. Learn more about UVA’s commitment to non-discrimination and equal opportunity employment.
Organization
In 1819, the University of Virginia established a new model for intellectual exchange and cross-disciplinary collaboration in higher education. Two hundred years later, as a major research institution, we continue to challenge conventions, lead with ingenuity and advance knowledge for the common good.
What began as an innovative idea has become one of the nation’s leading public research universities, with over 21,000 undergraduate, graduate and professional students. UVA also has over 3,000 full-time faculty offering more than 400 degrees.
Each of the University’s eleven schools has its own distinctive mission, working together to garner consistently high rankings—including #2 Best Value Public College (Princeton Review, 2016), #3 Public University in the Nation (U.S. News & World Report, 2016), and #3 Best Value Among Public Colleges (Kiplinger’s, 2016).
As we invest in and strengthen our research capabilities, UVA seeks new faculty ready to uncover new insights, rewrite old rules and collaborate on intellectual discoveries.
RESEARCH COLLABORATIONS THAT CROSS DISCIPLINES
As an R1 institution, the University’s research centers, consortia and laboratories are on the leading edge of discovery and technology, offering collaborative spaces for students and faculty to solve global problems.
Our professors are recognized members of major national scholarly and professional organizations, including the National Academy of Sciences and the American Academy of Arts and Sciences. Our faculty’s engagement in interdisciplinary research is being facilitated by new research institutes specializing in everything from big data to brain functioning, and by cluster hires across schools.
NATIONALLY RANKED HEALTH SYSTEM
UVA is also home to a nationally renowned academic medical center and the UVA Health System, which serves a three-part mission to treat patients, conduct translational research and train medical practitioners in a wide variety of disciplines.
Established as the nation’s 10th medical school in 1825, the institution has since grown to include a 612-bed hospital and a Level I trauma center, nationally recognized cancer and heart centers, a Children’s Hospital, and primary and specialty clinics throughout Central Virginia.
The UVA Medical Center is consistently ranked among the nation’s best hospitals by the U.S. News & World Report magazine and has been named among the top 25 percent in seven specialties.
INSPIRING STUDENTS, INSPIRED TEACHING
The vast majority of UVA students come from the top 10% of their high school class, as well as from all 50 states, over 142 countries and a variety of socioeconomic backgrounds. Despite their diversity, all UVA students share a love of learning and a drive to achieve.
One of the reasons students choose Virginia is our unique residential culture. At UVA, the community of students, faculty and staff personifies the Jeffersonian idea that living and learning are connected. The Academical Village was constructed to support a unique residential experience, with faculty living in the Pavilions, students occupying Lawn rooms and the world-famous Rotunda at its heart. The University’s residential culture continues to support this experience today—strengthened by students, faculty and staff rich in backgrounds, ideas and perspectives. Our unique culture is also paying dividends in innovation: UVA’s faculty have generated more than 130 patents since 2010.
Perhaps most importantly, faculty come to UVA knowing that instruction is as important as research, and they pride themselves on their many teaching awards. Our best professors look for ways to encourage, mentor and develop tomorrow’s leaders inside and outside the classroom.
LIFE IN CHARLOTTESVILLE
Living in Charlottesville you’ll find sophisticated restaurants, world-renowned wineries and breweries, cosmopolitan arts and music, friendly urban and suburban neighborhoods and a Piedmont landscape that has lured adventurous souls for centuries. No wonder the U.S. National Bureau of Economic Research named Charlottesville the “happiest city in America” in 2014.
In addition to UVA and its health system, several major employers have facilities in Charlottesville, including State Farm, Northrop Grumman, the U.S. Department of Defense, GE and others. Charlottesville is also becoming a center for innovative start-up businesses. The University also actively helps spouses and partners of faculty members build their networks and pursue employment opportunities with a wide variety of area employers.
The University of Virginia is an Equal Opportunity Employer. All interested persons are encouraged to apply including veterans and individuals with disabilities.
- Telephone
- 434-985-4532
- Location
-
2420 Old Ivy
Charlottesvle
Virginia
22911-7433
United States
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