Postdoctoral Fellow

Employer: University of Pennsylvania
Location: University of Pennsylvania, Perelman School of Medicine

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Employment Type: Full Time
Institution Type: Four-Year Institution

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Job Details
Organization

Postdoctoral Fellow

Location:
University of Pennsylvania, Perelman School of Medicine
Open Date:
Aug 7, 2026
Description:
The Wherry lab, in the Department of Systems Pharmacology and Translational Therapeutics, has an opening for a postdoctoral fellow to join a CRI-funded research project. This position is part of a larger CRI Initiative to establish a data resource that will enable data-driven innovation in immunotherapy and address the translational gap between preclinical models and clinical trials. This Immunotherapy Altas will incorporate comprehensive immune landscapes across commonly used mouse models as well as how these landscapes are altered when immunotherapy perturbations are applied. The goal for this position is to contribute to the establishment of this resource and to use it to address data-driven hypotheses that are generated based on analyses of this resource.

The postdoctoral fellow will lead this project in the Wherry lab and be instrumental in integrating similar data across two additional CRI-Immunotherapy Atlas labs. Experimental approaches to address the tumor-immune microenvironment will include flow cytometry, scRNA (+TCR)-seq, proteomics, and spatial analysis.

This position is an excellent opportunity to learn how to master cutting-edge technologies, leverage large datasets, generate data-driven hypotheses, and become a strong collaborative scientific leader.

Qualifications:
Successful candidates will have a PhD, MD, or MD/PhD degree, experience in immunology and/or cancer biology, a strong record of productivity, and a demonstrated ability to work independently and as a team.

Application Instructions:
To apply, please submit:

(1) A curriculum vitae
(2) A cover letter summarizing research experience and career goals
(3) The contact information of three references

Any questions can be directed to Dr. E. John Wherry (wherry@pennmedicine.upenn.edu)

Equal Employment Opportunity Statement:

The University of Pennsylvania is an equal opportunity employer. Candidates are considered for employment without regard to race, color, sex, sexual orientation, religion, creed, national origin (including shared ancestry or ethnic characteristics), citizenship status, age, disability, veteran status or any class protected under applicable federal, state, or local law.

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