GENERAL SUMMARY OF POSITION:
The Department of Biochemistry and Molecular Pharmacology strives to bring a molecular perspective to problems in biology and medicine. The Department currently has 23 faculty who, with over 200 postdoctoral fellows, research associates, graduate students and staff, conduct research on a wide variety of topics. Research topics include: mechanisms of protein folding, protein dynamics and assembly, bio-organic chemistry, RNA biology, structural biology, molecular modeling, molecular pharmacology, mechanisms of epigenetic inheritance, drug discovery, developmental biology, DNA repair and recombination, protein translocation mechanisms, gene expression, neuroscience and membrane biology. Collaborations with colleagues in other basic science and clinical departments enrich the possibilities for translating discoveries in basic science to clinical applications in our hospital. And the recently initiated development of companion programs in RNA Therapeutics, Stem Cell Biology and Gene Therapy portend new opportunities in translational research for our faculty and students.
The Bolon laboratory combines genetic and biochemical approaches to investigate the molecular underpinnings of adaptation. Potential rotation projects are available in two general (and partially overlapping) areas: exploring fitness landscapes through systematic approaches and investigating the molecular mechanism of the Hsp90 chaperone in signal transduction.
Under the direction of the Principal Investigator or Designee, the Research Associate performs a variety of complex research experiments.
- Conducts in-depth analysis of research experiments
- Performs complex laboratory experiments
- Interprets data, forms conclusion, and decides on and plans next experiments to be done with a high degree of independence
- Compiles and analyzes data and performs computations using image analysis software, spreadsheets, graphing, and curve fitting software
- May modify protocols and be responsible for a single, independent research project
- Assists in writing the text of scientific publications and grants. Reviews literature
- Trains new laboratory personnel, students, and collaborators
- Maintains laboratory supplies and equipment
- Complies with all safety and infection control standards
- Perform other duties as required.
- Bachelor’s degree in Biological Sciences, or equivalent experience
- 1 year relevant research experience
- Knowledge of Microsoft Office products
- Strong ability to analyze complex visual data in a quantitative and objective manner
- Judgment and action skills required to solve commonly encountered problems
- Experience working with Saccharomyces cerevisiae, DNA manipulations, and Illumina sequencing
May supervise/train lower level technicians or students in the lab.
Functions independently, use independent action in solving complex and unusual problems. Seeks guidance for unusual problems from Principal Investigator.
Manual dexterity to handle potentially hazardous chemicals and/or cleaners. Visual acuity to perform duties safely in a scientific laboratory.
Physical dexterity to lift 10-40 lb articles.
Must be able to carry out the essential functions of this position with reasonable accommodation if disabled.
ENVIRONMENTAL WORKING CONDITIONS:
Normal scientific laboratory conditions may work with hazardous materials and unpleasant odors.
As an equal opportunity and affirmative action employer, UMMS recognizes the power of a diverse community and encourages applications from individuals with varied experiences, perspectives and backgrounds.