Postdoc fellows in cancer immunology and cardiovascular biology
- Employer
- University of Pennsylvania
- Location
- Philadelphia
View more categoriesView less categories
- Employment Type
- Full Time
- Institution Type
- Four-Year Institution
Job Details
Postdoc fellows in cancer immunology and cardiovascular biology
Location: University of Pennsylvania - Perelman School of Medicine
Open Date: May 06, 2026
Deadline:
The Fan Laboratory in the Department of Radiation Oncology at the University of Pennsylvania''s Perelman School of Medicine is recruiting creative, collaborative, and highly motivated Postdoctoral Scientists to lead research projects in cancer immunology and cardiovascular biology.
Our lab investigates how the tissue microenvironment regulates cancer immunity and heart repair. We are particularly interested in:
- The molecular mechanisms underlying vascular control of immune cell function in cancer and ischemic heart disease;
- Targeting myeloid cells to overcome cancer-associated immunosuppression;
- The biology and therapeutic targeting of γδT cell and NKT cell exhaustion in cancer;
- Advanced radiation strategies, including FLASH and SFRT, to modulate tissue immunity in tumors and normal hearts.
Our research integrates mouse models, quantitative molecular and cell biology, immunology, metabolism, and multi-omics approaches-including transcriptomics, epigenomics, and proteomics-as well as advanced 3D imaging to uncover molecular pathways and develop novel therapeutic strategies. https://www.med.upenn.edu/apps/faculty/index.php/g20002840/p8679288.
Projects will be tailored to the interests of the successful candidate within broadly defined research themes, including:
• Molecular communication among endothelial cells, fibroblasts, macrophages, and dendritic cells
• Metabolic and transcriptional mechanisms regulating γδT cell dysfunction in the tumor microenvironment
• Combinatorial strategies integrating CAR-T cell therapy with FLASH- and SFRT-based radiotherapy
• Targeting endothelial plasticity and myeloid cell transitions to improve cardiac repair following ischemia
The Fan Lab emphasizes rigorous science, intellectual independence, and strong mentorship, supporting career trajectories with a strong track record of trainees advancing to independent faculty positions.
Qualifications
Required Qualifications
• PhD in Cancer Biology, Immunology, Cell Biology, or a related field
• Demonstrated research productivity, including first-author primary research publications
• Strong experimental and analytical skills in molecular, cellular, or tissue biology
• Ability to independently design and execute experiments
Preferred Qualifications
• Experience working with mouse models
• Background in metabolism and/or immunological analysis
• Experience in cancer and/or cardiovascular research workflows
• Bioinformatics skills (e.g., R, Python, or related tools)
Candidates requiring visa sponsorship are welcome to apply
Application Instructions
To apply, please submit:
- a curriculum vitae,
- a cover letter describing their research experience and interests
- a PDF of relevant publication(s)
- contact information for three references
Any questions can be directed to Dr. Yi Fan (fanyi@upenn.edu)
To apply, visit https://apply.interfolio.com/186048
Equal Employment Opportunity Statement
The University of Pennsylvania is an equal opportunity employer. Candidates are considered for employment without regard to race, color, sex, sexual orientation, religion, creed, national origin (including shared ancestry or ethnic characteristics), citizenship status, age, disability, veteran status or any class protected under applicable federal, state, or local law.
Copyright ©2025 Jobelephant.com Inc. All rights reserved.
Posted by the FREE value-added recruitment advertising agency jeid-d1c1be6c3bc574438e4b48c6413ef480
Organization
Welcome to the University of Pennsylvania! Penn is the largest private employer in Philadelphia and is a world-renowned leader in education, research, and innovation.
Across our 12 highly-regarded schools, more than 25,000 students, and more than 4,000 faculty members, we become one university: a wide-ranging, ever-changing community that draws its strength from a multitude of races, ethnicities, genders, sexual orientations, historical traditions, ages, religions, disabilities, veteran status, interests, perspectives, and socioeconomic backgrounds.
Penn carries on the principles and spirit of its founder, Benjamin Franklin: entrepreneurship, innovation, invention, outreach, and a pragmatic love of knowledge. Franklin's practical outlook has remained a driving force in the university's development. To learn more, visit About Penn.
Vision
As engines of knowledge and new ideas, universities have the unique potential to define the future rather than be defined by it; to pioneer change rather than merely manage it. To do so requires a plan both visionary and pragmatic. The Penn Compact 2022 motivates community members to innovate, be radically inclusive, and positively impact their local, national, and global communities.
Penn’s fundamental priorities — increasing access, integrating knowledge and engaging locally, nationally and globally — are supported by the three core values that make us uniquely Penn: inclusion, innovation, and impact.
Learn about the signature initiatives of the Penn Compact 2022:
- Global Connections President’s Engagement Prizes President's Innovation Prize Penn Integrates Knowledge University Professors
Diversity
Understanding and appreciating diversity is one of Penn's most important priorities and is fundamental to success in today's world.
Penn adheres to a policy that prohibits discrimination on the basis of race, color, sex, sexual orientation, gender identity, religion, creed, national or ethnic origin, citizenship status, age, disability, veteran status, or any other legally protected class.
To learn more about Diversity and Inclusion at Penn visit:
- Diversity at Penn Resources Supporting Diversity Penn Diversity Facts and Figures Penn's Diversity Timeline 1740-1997
Benefits
Penn offers a wide range of benefits and perks - from Penn's retirement Matching Plan to bike repair stations to access to the full LinkedIn Learning library to adoption assistance to workshops at the letterpress and book arts studio and much more!
- Penn HR Benefits Be in the Know Wellness Campaign Penn Home Ownership Services Campus Shuttles & Buses Resources for Cyclists Deals@Penn Common Press
Campus and Beyond
We invite you to explore our campus and its stately buildings and state-of-the-art facilities.
- Penn Park Morris Arboretum Penn Campus Arboretum: 6,800 Campus Trees Penn Recreation Penn Libraries Shop Penn
Try our self-guided tour! Come and visit!
Learn about sustainability at Penn.
News
Stay up-to-date with Penn's response to COVID-19: Coronavirus Information & Resources.
Penn supports news publications that tell the ongoing story of the University community, communications services for external media, telephone and video services, and other media resources: Campus Media
Connect with us!
- Telephone
- (215) 898-7372
- Location
-
3451 Walnut Street
Philadelphia
PA
19104
United States
Get job alerts
Create a job alert and receive personalized job recommendations straight to your inbox.
Create alert