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Director and Endowed Chair, Medicinal Chemistry-Associate Professor Rank

Job Details

Current UC employees must apply internally via SuccessFactors >

Founded in 1819, the University of Cincinnati ranks among the nation’s best urban public research universities. Home to more than 50,000 students, 11,000 faculty and staff and 340,000 alumni, UC combines a Top 35 public research university with a physical setting The New York Times calls “the most ambitious campus design program in the country.”

With the launch of Next Lives Here, the Cincinnati Innovation District, a $100 million JobsOhio investment, nine straight years of record enrollment, worldwide leadership in cooperative education, a dynamic academic health center and entry into the Big 12 Conference, UC’s momentum has never been stronger. UC’s annual budget tops $1.65 billion and its endowment totals $1.8 billion. The University’s overall regional economic impact exceeds $10.6 billion, paving the way for the future of Cincinnati.

Job Overview

The University of Cincinnati’s James L. Winkle College of Pharmacy (COP) and the College of Medicine’s (COM’s) Department of Internal Medicine announce a tenure-track faculty position of associate professor rank for an accomplished mid-career medicinal chemist. The successful applicant for the Winkle Chair in Medicinal Chemistry will serve as the medicinal chemistry director for the emerging Cancer Drug Development Institute (CDDI) at the University of Cincinnati (UC). The CDDI will be under the UC Cancer Center, comprised of investigators in the COM, COP, Cincinnati Children’s Hospital Medical Center, and UC Health (clinical arm of adult cancer medicine). The position’s planned start date is August 15, 2024 so that the medicinal chemistry lab will be operational before the end of the calendar year, independent of the CDDI timetable. Primary and secondary faculty appointments will be in the COP and COM, respectively. A ~2000 sq. ft. medicinal chemistry laboratory space plus additional labs for computational and drug assay work are immediately available to the hire, along with a generous start-up package.

Essential Functions
  • Serve as Director for CDDI at the University of Cincinnati;
  • Collaborate as co-investigator with UC cancer researchers toward achieving NCI program project grants and novel lead compound design, discovery and development
  • Obtain PI-level external funding and development of an independent research program are encouraged to the extent that time remains for collaboration with UC cancer researchers
  • Minimal teaching of medicinal chemistry classes may be expected, depending on research workload.
  • Attend meetings, participate in governance, prepare materials for teaching.
  • Serve on college or university committees and participate in curriculum development activities.
  • Review, and where necessary, respond in a timely manner to all University-related communications.
  • Other related duties as assigned.
Minimum Requirements
  • PHD in medicinal chemistry or synthetic organic chemistry, prior to effective date of appointment.
  • Demonstrated excellence in teaching and research evidenced by strong publication record in peer-reviewed journals. Candidates for a tenured appointment should demonstrate intellectual leadership and impact on the field and potential significant contributions to the department, University of Cincinnati, and wider scholarly community.
  • Experience with design/synthesis of PROTACs and other targeted protein degradation systems, commercialization of new molecular entities, and authorships on patents is desirable but not required.
  • Evidence of extramural funding history; Provision of partial salary support via external funding.
  • Experience in computational chemistry, virtual drug design and hit-to-lead compound discovery.
  • Application ProcessInterested candidates must apply online at for position 95575. Please complete an online applicant profile and upload your complete curriculum vitae, including a cover letter summarizing professional experience, a 1-page research statement describing specifically how your abilities could contribute to the CDDI. Include three professional references with contact information.

    Applications will be reviewed until the position is filled. This position is not eligible for H-1B sponsorship

    Physical Requirements/Work EnvironmentCompensation and Benefits

    UC offers a wide array of complementary and affordable benefit options, to meet the financial, educational, health, and wellness needs of you and your family. Eligibility varies by position and FTE.

    • Competitive salary range dependent on the candidate's experience.
    • Comprehensive insurance plans including medical, dental, vision, and prescription coverage.
    • Flexible spending accounts and an award-winning employee wellness program, plus an employee assistance program.
    • Financial security via our life and long-term disability insurance, accident and illness insurance, and retirement savings plans.
    • Generous paid time off work options including vacation, sick leave, annual holidays, and winter season days in addition to paid parental leave.
    • Tuition remission is available for employees and their eligible dependents.
    • Enjoy discounts for on and off-campus activities and services.

    As a UC employee, and an employee of an Ohio public institution, if hired you will not contribute to the federal Social Security system, other than contributions to Medicare. Instead, UC employees have the option to contribute to a state retirement plan (OPERS, STRS) or an alternative retirement plan (ARP).

    To learn more about why UC is a great place to work, please visit our careers page at

    For questions about the UC recruiting process or to request accommodations with the application, please contact Human Resources at

    The University of Cincinnati is an Equal Opportunity Employer.

    REQ: 95575



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