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Research Associate (Limited Term)

University of Toronto
: St. George (Downtown Toronto)

Job Details

Research Associate (Limited Term)

Date Posted: 12/18/2023
Req ID:35455
Faculty/Division: Temerty Faculty of Medicine
Department: Dept of Molecular Genetics
Campus: St. George (Downtown Toronto)


About Us
The Department of Molecular Genetics in the Temerty Faculty of Medicine, University of Toronto invites applications for the position of Research Associate (Limited Term) to participate in research focused on the molecular mechanisms of Cell Division and the available position will follow up on recent discoveries underpinning the regulation of distinct actin networks required for successful cell division in mammalian cells (Nat Comm 2021 12:2409, J. Biol. Chem 2020 295:3134) and expand in to other cellular roles of actin.

• Establishment, growth and propagation of mammalian tissue culture cells.
• Analysis of the cytoskeleton by fixed cell fluorescent microscopy, confocal and high-resolution microscopy.
• Live cell imaging of cell and cytoskeletal dynamics coupled with quantitative computational image analysis.
• Molecular Biology strategies to generate recombinant protein and mutant mammalian cell lines.
• Protein purification using affinity chromatography and analysis of protein-protein interactions using standard binding assays and BLI.
• Designing, planning, and executing research projects.
• Reading published papers relevant to the experiments being performed and adapting procedures accordingly.
• Liaising with collaborators and assisting in the compilation, analysis, and reporting of research findings to researchers within and outside of the program.
• Preparing manuscripts for submission to peer reviewed publications/journals.
• Presenting findings at local, national, and international conferences.
• Assisting with general laboratory biosafety and maintenance, including inventories, equipment repair, ordering, and shipping reagents.
• Coordinating efforts with a dynamic and productive team with diverse expertise.

Beyond these responsibilities, the individual will be expected to participate in the preparation of grant applications and in the supervision of technical support personnel and research trainees. At all times, the individual will be expected to support the overall research and teaching missions of the lab.

Candidates require a Ph.D. and expertise in biochemistry and microscopy. At least 10 years of experience in studying the cytoskeleton and cell migration. Extensive experience in both fixed and live cell analysis, confocal microscopy, image analysis and the application of application of microfluidics. A strong background in cytoskeleton biology is required and the application biochemical techniques (in particular protein expression and purification and in vitro binding assays) to study cytoskeletal dynamics especially during EMT will be an asset. Candidates must have experience preparing manuscripts for submission to peer reviewed publications/journals and in presenting findings at meetings and conferences. Candidates must also have experience designing, planning, and executing experiments and research. Strong organizational, interpersonal and communication skills are required, and a proven ability to work positively with others in a collaborative laboratory environment is an asset.

This is a term position of 2 years.

Closing Date: 03/18/2024,11:59PM ET
Employee Group: Research Associate
Appointment Type: Grant - Term
Schedule: Full-Time
Pay Scale Group & Hiring Zone: R01 -- Research Associates (Limited Term): $51,543 - $96,643
Job Category: Research Administration & Teaching

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All qualified candidates are encouraged to apply; however, Canadians and permanent residents will be given priority.

Diversity Statement

The University of Toronto embraces Diversity and is building a culture of belonging that increases our capacity to effectively address and serve the interests of our global community. We strongly encourage applications from Indigenous Peoples, Black and racialized persons, women, persons with disabilities, and people of diverse sexual and gender identities. We value applicants who have demonstrated a commitment to equity, diversity and inclusion and recognize that diverse perspectives, experiences, and expertise are essential to strengthening our academic mission.

As part of your application, you will be asked to complete a brief Diversity Survey. This survey is voluntary. Any information directly related to you is confidential and cannot be accessed by search committees or human resources staff. Results will be aggregated for institutional planning purposes. For more information, please see

Accessibility Statement

The University strives to be an equitable and inclusive community, and proactively seeks to increase diversity among its community members. Our values regarding equity and diversity are linked with our unwavering commitment to excellence in the pursuit of our academic mission.

The University is committed to the principles of the Accessibility for Ontarians with Disabilities Act (AODA). As such, we strive to make our recruitment, assessment and selection processes as accessible as possible and provide accommodations as required for applicants with disabilities.

If you require any accommodations at any point during the application and hiring process, please contact

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