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Founded in 1819, the University of Cincinnati ranks among the nation’s best urban public research universities. Home to nearly 48,000 students, about 11,000 faculty and staff and 332,000 alumni, UC combines a Top 35 public research university with a physical setting The New York Times calls “the most ambitious campus design program in the country.”

With the launch of Next Lives Here, the Cincinnati Innovation District, a $100 million JobsOhio investment, eight straight years of record enrollment, worldwide leadership in cooperative education, a dynamic academic health center and entry into the Big 12 athletic conference, UC’s momentum has never been stronger. UC’s annual budget tops $1.65 billion and its endowment totals $1.8 billion.

Job OverviewAs one of the oldest medical schools in the country, the UC College of Medicine has a reputation for training best-in-class health care professionals and developing cutting-edge procedures and research that improves the health and clinical care of patients. A full time Post Doc Fellow position is available in the laboratory of Dr. Jun-Lin Guan in the Department of Cancer Biology at the University of Cincinnati College of Medicine.

This position will pursue basic and translational cancer research. Research in Dr. Guan’s laboratory aims to understand the fundamental principles of cell signaling in the regulation of basic cellular functions in normal cell and developmental processes and to determine how the disruption of normal signaling pathways lead to cancer and other diseases. We are a well-established laboratory with extensive experiences and contributions in cancer research as well as strong training record for postdocs for more than 30 years at Cornell University, University of Michigan, and University of Cincinnati. Many of the former trainees went on for successful independent academic and other positions in the US and elsewhere. Please visit https://med.uc.edu/depart/cancer-biology/labs/guan-laboratory for more information on our laboratory.

We are interested in recruiting self-motivated, recent Ph.D. or M.D./Ph.D. graduates with the drive to succeed and the desire to be competitive at the highest level. The new postdoc will pursue studies on breast cancer metastasis and/or mechanisms of progression of vascular malformation to angiosarcoma using several unique mouse models of the diseases recently established in the laboratory. The trainee will gain experience in multiple state-of-the-art approaches including CRISPR-based genetic screen, single cell transcriptomics, proteomics and genomics, organoids, and optogenetics for studies of multifaceted roles of autophagy, intracellular protein trafficking and other fundamental cellular processes in cancer progression and metastasis in vivo. Please see Publications | Guan Laboratory | Faculty Research Labs | Cancer Biology | COM (uc.edu) for recent papers from our laboratory.

Essential Functions

Conduct research experiments in a particular field within research scope and methodology of cell signaling in the regulation of basic cellular functionsGather and analyze data and develop new ideas that promote current research.Prepare data summaries, reports, manuscripts and presentations of research results.Participate/assist in manuscript writing for publication in scientific journals and/or presentation; may assist in grant writing.Keep informed of developments in field to maintain and enhance professional expertise.Lab maintenance, including equipment maintenance and ordering of supplies, as needed.May teach techniques to others, train, and mentor junior research staff.Engage in appropriate training and professional development opportunities. Play an active role in seeking career and research advice, both from the faculty supervisor and from other faculty members as well. Perform related duties based on departmental need. This job description can be changed at any time.

Required Education

Doctoral Degree in biological sciences, or the equivalent foreign equivalent.

Additional Qualifications Considered

• Candidates with a strong background in cell and molecular biology, cancer research, neuroscience, vascular biology immunology and/or bioinformatics.
• Experience in autophagy, cell signaling, vesicle trafficking, single-cell transcriptional and genomic analysis, and mouse models of cancer or other diseases.

Application InstructionsPlease complete an online application and attach:

• Curriculum vitae
• Statement of research interests

Please use the Additional Documents option as needed for these documents. Contact information of three references via e-mail to Dr. Jun-Lin Guan (guanjl@uc.edu). Please email Dr. Guan with any questions and/or set up a time to meet in person.

Physical Requirements/Work Environment

Sitting - Continuously

Compensation and Benefits

UC offers a wide array of complementary and affordable benefit options, to meet the financial, educational, health, and wellness needs of you and your family. Eligibility varies by position and FTE.

• Competitive salary range dependent on the candidate's experience.
• Comprehensive insurance plans including medical, dental, vision, and prescription coverage.
• Flexible spending accounts and an award-winning employee wellness program, plus an employee assistance program.
• Financial security via our life and long-term disability insurance, accident and illness insurance, and retirement savings plans.
• Generous paid time off work options including vacation, sick leave, annual holidays, and winter season days in addition to paid parental leave.
• Tuition remission is available for employees and their eligible dependents.
• Enjoy discounts for on and off-campus activities and services.

To learn more about why UC is a great place to work, please visit our careers page at https://www.uc.edu/careers.html.

The University of Cincinnati, as a multi-national and culturally diverse university, is committed to providing an inclusive, equitable and diverse place of learning and employment. As part of a complete job application you will be asked to include a Contribution to Diversity and Inclusion statement.

As a UC employee, and an employee of an Ohio public institution, if hired you will not contribute to the federal Social Security system, other than contributions to Medicare. Instead, UC employees have the option to contribute to a state retirement plan (OPERS, STRS) or an alternative retirement plan (ARP).

The University of Cincinnati is an Affirmative Action / Equal Opportunity Employer / Minority / Female / Disability / Veteran.

REQ: 93743

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