Research Associate - Ulijasz Lab

Research Associate - Ulijasz Lab

University Faculty

Full-Time

Exempt

Maywood-Health Sciences Campus

MICROBIOLOGY (06220A)

MICROBIOLOGY

Yes

The Ulijasz lab (www.ulijaszlab.com) at Loyola University Chicago Department of Microbiology and Immunology is recruiting a highly motivated postdoctoral researcher to work on a recently NIH funded project in the area of molecular microbiology. Our lab researches molecular mechanisms of bacterial signal transduction/sensors in both Gram-negative and Gram-positive bacterial pathogens. To accomplish this, we and our collaborators use a wholistic and innovative array of methods, including high-throughput sequencing, protein biochemistry/molecular biology, structural biology, super resolution microscopy and animal infections to reveal novel proteins and pathways that contribute to microbial disease.Using a novel screening method, metabolic-coupled tn-sequencing (Met-seq; Glanville et al. mSystems, 2021), the Ulijasz lab has recently discovered a subset of protein domains that bind heme and sense and responds to glyoxal; a ubiquitous toxin that results from glycolysis. The accumulation of glyoxal (and methylglyoxal) is thought to be an underlying cause of many human diseases though its irreversible damage to key proteins. In prokaryotes the mechanisms of glyoxal sensing and response are especially enigmatic. The project will entail investigating how this novel family of proteins sensing and responds to glyoxal in the pathogen Pseudomonas aeruginosa, and possibly other microorganisms, using a series of molecular techniques.

The Ulijasz lab is located at Loyola University Chicago in the western Chicago suburbs. Located in the midwestern United States in the state of Illinois. Chicago is the third largest city in the US, and home to several national sports teams, a top-rated and ethnically diverse restaurant scene and world renowned entertainment. Housing is affordable and the city/surrounding areas offer accessible and safe public transit around the city.Interested candidates should send an application packet, including all the following by email to aulijasz@luc.edu.
1. Cover letter indicating current and future research interests;
2. Expected starting date3. Curriculum vitae;
4. Names and contact information for 3 references­­

Candidates should have a Ph.D. in Microbiology, Molecular Biology, Biochemistry or related field. The successful candidate will have a stron­­­g background in microbial genetics and molecular biology, including protein expression and purification, and the ability to conduct his/her research independently. The candidate will be working with several collaborating labs on aspects of the project. Applicants with a knowledge base in protein-protein interactions, and/or mass spectrometry and/or super resolution microscopy would be pre­ferred, but is not required.

Standing

Lighting, Heating, Ventilation, Odors

Candidates should have a Ph.D. in Microbiology, Molecular Biology, Biochemistry or related field. The ideal postdoctoral candidate will have a skill set of one or more of the following: bacterial genetics (e.g. cloning techniques), protein expression and purification and associated biochemical analyses such as examination of protein-DNA interactions using various methodologies. Experience with animal infection models is a plus.

02/07/2022

Diversity, Equity, and Inclusion

As one of the nation’s largest Jesuit, Catholic universities, Loyola University Chicago fosters a transformative cultural experience that honors diversity, equity, and inclusion. We are committed to not only recruiting, but also retaining a diverse, mission driven workforce and enabling a culture of inclusiveness in an environment that values service excellence, stewardship, personal well-being, and professional development for all of our employees. Loyola University Chicago supports its staff and faculty with a wide array of affordable, comprehensive and competitive benefits centered on health and wellness, financial security, equity, and work-life balance. We actively seek those who wish to join our faculty, staff, and students in a community of diverse opinions, perspectives, and backgrounds supporting our Jesuit mission and striving toward the same goal of being persons for and with others.

https://www.careers.luc.edu/postings/23989

8550528

HEALTH SCIENCES CAMPUS

Yes