Current UC employees must apply internally via SuccessFactors > http://bit.ly/UCEMPL

Founded in 1819, the University of Cincinnati ranks among the nation’s best urban public research universities. Home to more than 47,000 students, 10,500 faculty and staff and 330,000 alumni, UC combines a Top 35 research university with a physical setting The New York Times calls “the most ambitious campus design program in the country.”

With the launch of Next Lives Here, the Cincinnati Innovation District, a $100 million JobsOhio investment, eight straight years of record enrollment, worldwide leadership in cooperative education, a dynamic academic health center and entry into the Big 12 athletic conference, UC’s momentum has never been stronger. UC’s annual budget tops $1.6 billion and its endowment totals $1.9 billion.

Job Overview

The post-doctoral fellow will be a part of a multidisciplinary team working on a cutting-edge NIH-funded project focused on identifying most promising targeted agents for the treatment of glioblastoma (GBM). Applicants must have significant experience in conducting pharmacokinetics and pharmacodynamics (PK/PD) studies to facilitate the clinical translation of investigational agents for the treatment of GBM. The post-doctoral fellow will be expected to lead pre-clinical studies including mechanistic molecular studies, in vivo animal models (athymic nude mice and rats) for assessing systemic and brain penetration of drugs and anti-tumor efficacy studies. Additionally, the post-doctoral fellow will conduct correlative studies to facilitate clinical trials of identified drugs. Such studies will include biomarker and RNAseq analyses and in vitro/in vivo approaches for validating identified targets. Preference will be given to individuals with applicants with experience in pre-clinical imaging, bioanalysis of drugs in plasma and tissue samples (HPLC, LC/MS and ELISA) and PK/PD modeling and simulation.

Applicants must be energetic and collaborative and help with routine management of laboratory, including regulatory issues such as those required for animal and human studies, help doctoral students and other researchers. Candidates must be self-motivated and have a record of accomplishment. Strong organizational skills are necessary.

Essential Functions

• Design, execute, and record laboratory experiments, and analyze the data.
• Research and improve current methods and evaluate innovative techniques.
• Implement this knowledge in the Division/Department.
• Present research at laboratory meetings, journal clubs, seminars, and meetings.
• Draft, write, and edit scientific reports, papers, journal articles, abstracts, and grants.
• Set up and lead weekly lab meetings.

Required Education

Doctoral Degree in the appropriate field or discipline, or the recognized terminal degree, or the equivalent foreign equivalent.

Required Experience

• In-depth knowledge of specialized field, process or discipline.
• May require experience with specialized software programs.

Additional Qualifications Considered

• Required: Ph.D. in related discipline, MD, or equivalent degree.
• At least 2-3 experience in conducting pre-clinical and translational research to facilitate the development of oncology drugs.
• A record of high impact publications in cancer journals.
• Excellent written, verbal, and interpersonal communication skills.
• Demonstrate attention to detail, strong organizational skills, supervisory ability, and an innovative approach to experimental design.
• Proficient in the use of advanced softwares for PK/PD and statistical analysis.
• Ability to synthesize information and to create and deal with new situations by applying past experiences.
• Expressed willingness to teach others and share results.
• Capable of meeting time demands necessary to execute experiments.

Physical Requirements/Work Environment

Sitting - Continuously

Application Process

Applications are invited for a post-doctoral fellow to pursue development of neuro-oncology drugs in the laboratory of Dr. Pankaj B. Desai, Professor of Pharmaceutical Sciences, College of Pharmacy, University of Cincinnati. Interested and qualified applicants must:

• Apply online and include a cover letter of interest and a current CV/Resume.
• All certifications and other documentation can be uploaded using the Additional Documents section in the application.
• Applications without a cover letter and CV/Resume will not be considered for the position

Compensation and Benefits

UC offers a wide array of complementary and affordable benefit options, to meet the financial, educational, health, and wellness needs of you and your family. Eligibility varies by position and FTE.

• Competitive salary range dependent on the candidate's experience.
• Comprehensive insurance plans including medical, dental, vision, and prescription coverage.
• Flexible spending accounts and an award-winning employee wellness program, plus an employee assistance program.
• Financial security via our life and long-term disability insurance, accident and illness insurance, and retirement savings plans.
• Generous paid time off work options including vacation, sick leave, annual holidays, and winter season days in addition to paid parental leave.
• Tuition remission is available for employees and their eligible dependents.
• Enjoy discounts for on and off-campus activities and services.

The University of Cincinnati, as a multi-national and culturally diverse university, is committed to providing an inclusive, equitable and diverse place of learning and employment. As part of a complete job application you will be asked to include a Contribution to Diversity and Inclusion statement.

As a UC employee, and an employee of an Ohio public institution, if hired you will not contribute to the federal Social Security system, other than contributions to Medicare. Instead, UC employees have the option to contribute to a state retirement plan (OPERS, STRS) or an alternative retirement plan (ARP).

The University of Cincinnati is an Affirmative Action / Equal Opportunity Employer / Minority / Female / Disability / Veteran.

REQ: 91628

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