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The Hind Lab in the Department of Chemical and Biological Engineering at the University of Colorado Boulder is seeking a postdoctoral associate to work on a project aimed at understanding how diverse inflammatory signals regulate the neutrophil response to inflammation using engineered in vitro platforms designed to mimic in vivo biology with human cells. Neutrophils are critical to protecting the body from foreign invaders during an immune response; however, defective neutrophil recruitment, excessive neutrophil infiltration, or improperly controlled neutrophil function contributes to chronic infections, tissue damage, and the progression of diseases including cancer, cardiovascular disease, autoimmune disease, and fibrosis. The goal of this research project is to determine how secreted inflammatory signals and multicellular interactions regulate neutrophil behavior with the long-term goal of identifying targets to modulate neutrophil recruitment and function to treat infections and neutrophil-associated diseases. The researcher working on this project will have numerous opportunities to mentor graduate and undergraduate students and collaborate with other researchers at the University of Colorado Boulder and within the medical school at University of Colorado Anschutz.
The University of Colorado Boulder is committed to building a culturally diverse community of faculty, staff, and students dedicated to contributing to an inclusive campus environment. We are an Equal Opportunity employer, including veterans and individuals with disabilities.
Who We Are
The Hind research group is broadly interested in using engineered devices to study the innate immune response to infection. The innate immune response is a complicated process that involves numerous cell types and occurs in many different tissues throughout the body. In order to better understand both the chemical and biophysical mechanisms that drive the human immune response, we must study cellular behavior in physiologically relevant contexts. Our group designs microfluidic models inspired by in vivo biology that recapitulate many of the important cell-cell interactions and structural components of the infectious microenvironment. We then use these models to study how multicellular interactions and the physical environment influence innate immune cell function during infection. This multidisciplinary research is carried out using principles and techniques from engineering, immunology, molecular biology, and microscopy.
What Your Key Responsibilities Will Be
The primary responsibility to conduct high quality research by developing questions and hypothesis related to the function of neutrophils in inflammation and testing them through careful experimentation. Specific tasks related to these duties include but are not limited to:
What You Should Know
- Isolating and culturing a variety of primary human immune cells from blood
- Culturing various vascular cells including endothelial cells
- Developing, fabricating, and using microfluidic models of the inflammatory microenvironment
- Studying cellular function through cytokine panels and microscopy
- Mentoring graduate and undergraduate students
- Disseminating results through publications and conference talks
- Contributing data to and helping with proposal development
All University of Colorado Boulder employees are required to comply with the campus COVID-19 vaccine requirement
. New employees must provide proof of vaccination or receive a medical or religious exemption within 30 days of employment.
What We Can Offer
The salary range is $48,000-$60,000 per year.
The University of Colorado offers excellent benefits
, including medical, dental, retirement, paid time off, tuition benefit and ECO Pass. The University of Colorado Boulder is one of the largest employers in Boulder County and offers an inspiring higher education environment. Learn more about the University of Colorado Boulder
Be curious. Be resourceful. Be Boulder.
What We Require
What We Would Like You To Have
- A Ph.D. in Chemical Engineering, Bio- or Biomedical Engineering, Immunology, Cell Biology or a related field.
- Experience in microfluidics, cell culture, primary cell isolation and characterization, and/or immunology.
- Self-motivated and organized.
- An ability to work individually and collaboratively.
- An interest in mentoring junior scientists.
To apply, please submit the following materials:
- Cover Letter
- Transcripts/Proof of Degree
During the application process you will need to enter contact information for two references who will be contacted to provide letters of recommendation as the search progresses.
Applications will be accepted until the position is filled.
Note: Application materials will not be accepted via email. For consideration, please apply through CU Boulder Jobs
To apply, visit https://jobs.colorado.edu/jobs/JobDetail/Postdoctoral-Associate/42751
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