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Research Instructor

Employer
University of Colorado Anschutz Medical Campus
Location
Denver, CO

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Description

University of Colorado | CU Anschutz Medical Campus

School of Medicine, Department of Pediatrics, Section of Hematology, Oncology, and Bone Marrow Transplantation

Research Instructor

Position #00798581– Requisition #26534

 

 

* Applications are accepted electronically ONLY at www.cu.edu/cu-careers

The University of Colorado has a requirement for COVID-19 vaccinations and full completion thereof by 9/1/21 or upon start date.  Information regarding this requirement, and exemptions can be found at:

Anschutz: https://www.ucdenver.edu/docs/librariesprovider284/default-document-library/3000-general-admission/3012---covid-19-vaccination-requirement-and-compliance.pdf?sfvrsn=4e9df3ba_2

Denver: https://www.ucdenver.edu/coronavirus

Exemptions vary by campus location/department.

Campus/Unit-Specific Exemptions:

    Anschutz Campus – Exemptions are allowed for medical or religious reasons.Denver Campus - Exemptions are allowed for medical, religious, or personal reasons.Consolidated/Central Services Administration – Will follow Anschutz policy on exemptions.
The University of Colorado Anschutz Medical Campus seeks individuals with demonstrated commitment to creating an inclusive learning and working environment. We value the ability to engage effectively with students, faculty and staff of diverse backgrounds.

Department of Pediatrics, Section of Hematology, Oncology, and Bone Marrow Transplantation has an opening for a full-time Research Instructor position. 

Nature of Work:

    This person will be involved in conducting laboratory research in pediatric brain tumors.  The studies will involve examination of chromatin biology, drug resistance ant metabolic reprograming of brain tumors primarily focused on medulloblastoma. The individual will conduct experiments; assist with project planning, data interpretation, training scientists, students, and volunteers; as well as authorship of presentations and publications.The individual will develop new approaches and avenues of investigation and assist with writing grants including NIH applications.Seeking a motivated and experienced scientist who has the initiative and skill set to take charge on in vivo projects, specifically murine models, and is well versed with molecular lab techniques including chromatin biology.  The individual will be responsible from start (designing) to finish (expression in cells) and is willing and able to mentor students and new lab members.
The University of Colorado Anschutz Medical Campus is a world-class medical destination at the forefront of transformative science, medicine, education and patient care. The campus encompasses the University of Colorado health professional schools, more than 60 centers and institutes, and two nationally ranked independent hospitals - UCHealth University of Colorado Hospital and Children's Hospital Colorado - that treat more than two million adult and pediatric patients each year. Innovative, interconnected and highly collaborative, the University of Colorado Anschutz Medical Campus delivers life-changing treatments, patient care and professional training and conducts world-renowned research fueled by over $650 million in research grants. For more information, visit www.cuanschutz.edu.

Position Emphasis:

The duties and responsibilities of the position include, but are not limited to:

  • Culturing of human brain tumor cells, neural stem cells, induced pluripotent stem cells (iPS) and differentiation of these cells into neuronal cells.
  • Performing chromatin assays including ChIP-Seq, CUT&RUN and Hi-ChIP.
  • Analysis of metabolic activity.
  • Extensive murine model work under the scope of cancer and cancer-predisposition models.
  • Conducting experiments using techniques including, qPCR, cloning, transfection/transduction, protein/RNA extraction, single cell sequencing, immunofluorescence microscopic cell imaging.
  • Incucyte cytotoxicity assays.
  • Preparing data for discussion and presentation.
  • Attending and presenting at lab meetings.
  • Assisting with lab organization and upkeep.
  • Assisting in or producing publications.
  • Assisting in writing Grant applications.
PLEASE NOTE: Candidates will be responsible for travel expenses related to the interview process and any relocation expenses, if applicable.

Salary and Benefits:

The hiring rate for this position has been established at $80,000.

The salary of the finalist(s) selected for this role will be set based on a variety of factors, including but not limited to, internal equity, experience, education, specialty and training.

The above salary range (or hiring range) represents the University’s good faith and reasonable estimate of the range of possible compensation at the time of posting.

Your total compensation goes beyond the number on your paycheck. The University of Colorado provides generous leave, health plans and retirement contributions that add to your bottom line.

 Benefits: https://www.cu.edu/employee-services/benefits

Total Compensation Calculator: http://www.cu.edu/node/153125

Diversity and Equity:

The University will provide reasonable accommodations to applicants with disabilities throughout the employment application process. To request an accommodation pursuant to the Americans with Disabilities Act, please contact the Human Resources ADA Coordinator at [email protected].

The University of Colorado Denver | Anschutz Medical Campus is committed to recruiting and supporting a diverse student body, faculty and administrative staff. The university strives to promote a culture of inclusiveness, respect, communication and understanding. We encourage applications from women, ethnic minorities, persons with disabilities, persons within the LGBTQ+ community, and all veterans. The University of Colorado is committed to diversity and equality in education and employment.

The University of Colorado Denver | Anschutz Medical Campus is dedicated to ensuring a safe and secure environment for our faculty, staff, students and visitors. To assist in achieving that goal, we conduct background investigations for all prospective employees.



Qualifications
Minimum Qualifications

Applicants must meet minimum qualifications at the time of hire.

  • Doctor of Philosophy (PhD) degree in a biological science field or related field + 6 years of professional laboratory experience.
  • Extensive murine experience including, but not limited to: maintenance of colonies; injections and implantations; drug treatment  (oral and IP), tissue harvesting. Must be able to independently design murine studies from start to finish.
  • Can independently construct primers and manipulate plasmid constructs; transform and isolate plasmid DNA; and utilize said DNA for lentiviral transductions of both primary cells and cell lines.
  • Cell culture and maintenance of various cell lines.
  • Expertise with Chromatin assasy including ChIP-Seq, CUT&RUN and Hi-ChIP.
  • Analysis of RNA-seq.
  • Prior experience mentoring students/staff.
Condition of Employment

  • Must be willing and able to pass a national criminal background check.
Knowledge, Skills, and Abilities

  • Good verbal and written communications.
  • Ability to stay organized under pressure.
  • Knowledgeable of professional laboratory protocols.
  • Ability to complete lab functions involving cell culture and aseptic techniques.
  • Competency with molecular biology techniques.
  • Ability to complete live cell binding assays.
  • Animal experience (designing/mouse handling/injections/harvesting/sacrificing).
  • Background in immunology and stem cell biology.
  • Experience handing human blood products, specifically stem cells.
  • Ability to troubleshoot and independently resolve technical issues with experiments.
  • Ability to perform 2+ color flow cytometry.
Preferred Qualifications

  • Doctor of Philosophy (PhD) degree in Cancer Biology or related field.
  • Chromatin Biology experience.
  • Previous experience in presenting and/or aiding in publications and grant preparation.
  • Competency with Flowjo, Microsoft office, Prism Graphpad, Metascape, Gene set enrichment analysis and Immunohistochemistry.


Job Category: Faculty
Primary Location: Aurora
Schedule: Full-time
Posting Date: Jun 28, 2022
Unposting Date: Jul 4, 2022, 12:59:00 AM
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