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Medicinal Chemist II

University of Florida
Main Campus (Gainesville, FL)

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Administrative Jobs
Institutional & Business Affairs, Health & Medical Services
Employment Type
Full Time
Institution Type
Four-Year Institution
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Job no: 521805
Work type: Staff Full-Time
Location: Main Campus (Gainesville, FL)
Categories: Research/Scientific/Grants
Department:32040000 - PH-PHARMACODYNAMICS

Classification Title:

Chemist II

Job Description:

This Intermediate Chemist position (Chemist II) works in a Medicinal Chemistry laboratory setting, assists the Principal Investigator (PI) in the design and synthesis of small organic molecules in Hit-to-Lead and Lead optimization projects. The position performs synthesis, purification, and characterization of small organic molecules under supervision of the PI and collaborates closely with biologists for the biochemical and pharmacological evaluation. This position is also expected to perform literature search and assist in synthetic route selection and experiment design. This position responsibilities will also include routine maintenance of laboratory equipment, managing compound library and chemical inventory, ordering lab supplies, as well as maintaining a safe, clean work environment. Other responsibilities include reporting results to PI and in lab meetings and assist in the writing of publications and reports.

Duties include:

  • Prepare and carry out synthetic experiments, including set up of reactions and work up.
  • Conduct purification of the products and characterization of the structure and purity of the product.
  • Maintain laboratory equipment, clean lab and fume hoods, handle hazardous waste, manage compound library, manage chemical inventory, order lab supplies, coordinate with biologists for testing samples in bioassays, train students and lab technician on the use of lab instruments.
  • Search literature, assist PI in synthetic route selection and experiment design, coordinate with biologists with sample submission for testing. Record experimental procedures and data on lab notebook, report results to PI and in lab meetings, assist in writing manuscripts and reports. Perform other duties as assigned by supervisor.

The University of Florida, College of Pharmacy, strives to stimulate a culture that promotes diversity and inclusion within an exceptional community of students, faculty and staff. We welcome applicants from diverse backgrounds and are committed to developing leaders who respect, support and have a positive impact on all individuals. In recognition of its efforts to cultivate a diverse and inclusive environment, the College of Pharmacy was the recipient of a 2021 Insight into Diversity Health Professions Higher Education Excellence in Diversity Award.

Expected Salary:

Commensurate with education and experience.

Minimum Requirements:

A Bachelor's degree in chemistry or a closely related field and three years of relevant experience; or a master's degree in chemistry or a closely related field and one year of relevant experience; or Doctoral degree in chemistry or a closely related field.

Preferred Qualifications:

Strong organic synthesis training established through performance at bench and through coursework. Able to interpret 1D NMR spectra and LCMS data. Able to search and read chemistry literature and procedures and apply in own work projects. Hand-on experience on the use of NMR, LC-MS, and preparative-HPLC. Experience with modeling and structure-guided design of molecules will be a plus. Have working knowledge of drug design and structure-activity relationship analysis. Experience in a drug discovery and development research environment. Good organizational skills to adapt to fluctuating workloads while maintaining appropriate attention to detail. Ability to handle multiple projects and prioritize. Demonstrated ability to follow established laboratory safety procedures, to maintain accurate records, and clearly and accurately read and write and transcribe data. Good communications skills-verbal and written communication. Good interpersonal skills with the ability to work independently or as a member of a team.

Special Instructions to Applicants:

In order to be considered, you must upload your cover letter, resume, and list of references.

This is a time-limited position.

Application must be submitted by 11:55 p.m. (ET) of the posting end date.

Health Assessment Required:No

Advertised: 04 May 2022 Eastern Daylight Time
Applications close: 01 Jun 2022 Eastern Daylight Time

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