BIOSTATISTICIAN I

Employer
Duke University
Location
Molecular Physiology

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Employment Type
Full Time
Institution Type
Four-Year Institution

Job Details

School of Medicine Established in 1930, Duke University School of Medicine is the youngest of the nation’s top medical schools. Ranked sixth among medical schools in the nation, the School takes pride in being an inclusive community of outstanding learners, investigators, clinicians, and staff where interdisciplinary collaboration is embraced and great ideas accelerate translation of fundamental scientific discoveries to improve human health locally and around the globe. Composed of more than 2,500 faculty physicians and researchers, more than 1,300 students, and more than 6,000 staff, the Duke University School of Medicine along with the Duke University School of Nursing, Duke University Health System and the Private Diagnostic Clinic (PDC) comprise Duke Health. a world-class academic medical center. The Health System encompasses Duke University Hospital, Duke Regional Hospital, Duke Raleigh Hospital, Duke Primary Care, Duke Home and Hospice, Duke Health and Wellness, and multiple affiliations.

Duke Molecular Physiology Institute isrecruiting a biost atisticianunder the supervision of Dr. Yi-Ju Li

Drug Ind uced Liver Injury Network(DILIN) was established by the National Institu te of Diabetes and KidneyDiseases (NIDDK) of the National Institute of H ealth (NIH) in 2003. The goal isto understand risk factors for drug indu ced liver injury (DILI), includinggenetic risk factors. DILIN has six cl inical sites to screen and enrollpatients with DILI to the network, and one Data Coordination Center (DCC) toprovide data management and statist ical collaboration. DILIN DCC is led byprincipal investigator (PI), Dr. Huiman Barnhart at Duke Clinical ResearchCenter (DCRI).Dr .Yi-JuLi at DukeMolecular Physiology Institute (DMPI) serves as a co-i nvestigator of DILIN DCCto lead the analysis of genetic projects. </span >

Responsibility:</stron g>

You will work on projects for Drug I nduced Liver Injury Network(DILIN). As this is a multicenter network, yo u will work with differentclinical investigators in DILIN under Dr. Yi-J u Li’s direction.

Your major responsibilities will include:

· Developstatistical analysis plan ( SAP) for each project.

·Responsiblefor the data management of DILIN genetic d ata. Monthly clinical data update andavailable genetic data should be da tabased in Pedigene.

·</s pan>Responsiblefor querying data for each project. < /p>

·Conduct stat istical data analysis followingthe analysis strategies outlined in SAP f or each project. This will include butnot limited to genome wide associa tion tests for traits of interest, HLAassociation tests for trait of int erest, imputation of genotype data, pathwayanalysis, etc.

·Preparesummary rep ort and maintain excellent documentation for each project.

·Writeanalysis prog rams including SAS, R, PLINK, UNIX shell scripts with informativeannotat ions.

·Applyany related bioinformatic tools to genetic projects.

·Generate figures and tables related tothe results.

·Prepare analysis reports.

·

Assistwith manuscript development and grant proposal preparation.

· Performother related duties and special projects as requested.


Minimum Qualifications


Education

Work requires a Bachelor's degree in (bio)statistics or related field.


Experience

No experiencerequired beyond that obtained through education.

Duke is an Affirmative Action/Equal Opportunity Employer committed to providing employment opportunity without regard to an individual's age, color, disability, gender, gender expression, gender identity, genetic information, national origin, race, religion, sex, sexual orientation, or veteran status.

Duke aspires to create a community built on collaboration, innovation, creativity, and belonging. Our collective success depends on the robust exchange of ideas—an exchange that is best when the rich diversity of our perspectives, backgrounds, and experiences flourishes. To achieve this exchange, it is essential that all members of the community feel secure and welcome, that the contributions of all individuals are respected, and that all voices are heard. All members of our community have a responsibility to uphold these values.

Essential Physical Job Functions: Certain jobs at Duke University and Duke University Health System may include essentialjob functions that require specific physical and/or mental abilities. Additional information and provision for requests for reasonable accommodation will be provided by each hiring department.

Organization

Read our Diversity Profile History

Duke University was created in 1924 by James Buchanan Duke as a memorial to his father, Washington Duke. The Dukes, a Durham family that built a worldwide financial empire in the manufacture of tobacco products and developed electricity production in the Carolinas, long had been interested in Trinity College. Trinity traced its roots to 1838 in nearby Randolph County when local Methodist and Quaker communities opened Union Institute. The school, then named Trinity College, moved to Durham in 1892, where Benjamin Newton Duke served as a primary benefactor and link with the Duke family until his death in 1929. In December 1924, the provisions of indenture by Benjamin’s brother, James B. Duke, created the family philanthropic foundation, The Duke Endowment, which provided for the expansion of Trinity College into Duke University.Duke Campus

As a result of the Duke gift, Trinity underwent both physical and academic expansion. The original Durham campus became known as East Campus when it was rebuilt in stately Georgian architecture. West Campus, Gothic in style and dominated by the soaring 210-foot tower of Duke Chapel, opened in 1930. East Campus served as home of the Woman's College of Duke University until 1972, when the men's and women's undergraduate colleges merged. Both men and women undergraduates now enroll in either the Trinity College of Arts & Sciences or the Pratt School of Engineering. In 1995, East Campus became the home for all first-year students.

Duke maintains a historic affiliation with the United Methodist Church.

Home of the Blue Devils, Duke University has about 13,000 undergraduate and graduate students and a world-class faculty helping to expand the frontiers of knowledge. The university has a strong commitment to applying knowledge in service to society, both near its North Carolina campus and around the world.

Mission Statement

Duke Science"James B. Duke's founding Indenture of Duke University directed the members of the University to 'provide real leadership in the educational world' by choosing individuals of 'outstanding character, ability, and vision' to serve as its officers, trustees and faculty; by carefully selecting students of 'character, determination and application;' and by pursuing those areas of teaching and scholarship that would 'most help to develop our resources, increase our wisdom, and promote human happiness.'

“To these ends, the mission of Duke University is to provide a superior liberal education to undergraduate students, attending not only to their intellectual growth but also to their development as adults committed to high ethical standards and full participation as leaders in their communities; to prepare future members of the learned professions for lives of skilled and ethical service by providing excellent graduate and professional education; to advance the frontiers of knowledge and contribute boldly to the international community of scholarship; to promote an intellectual environment built on a commitment to free and open inquiry; to help those who suffer, cure disease, and promote health, through sophisticated medical research and thoughtful patient care; to provide wide ranging educational opportunities, on and beyond our campuses, for traditional students, active professionals and life-long learners using the power of information technologies; and to promote a deep appreciation for the range of human difference and potential, a sense of the obligations and rewards of citizenship, and a commitment to learning, freedom and truth.Duke Meeting

 “By pursuing these objectives with vision and integrity, Duke University seeks to engage the mind, elevate the spirit, and stimulate the best effort of all who are associated with the University; to contribute in diverse ways to the local community, the state, the nation and the world; and to attain and maintain a place of real leadership in all that we do.”

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