Assoc. Scientist - CNVs

University of Miami
Miami, FL

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Employment Type
Full Time
Institution Type
Four-Year Institution
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Transforming Lives

The University of Miami is among the top research universities and academic medical centers in the nation, and one of the largest private employers in South Florida.

With more than 16,000 faculty and staff, the University strives for excellence, and is driven by a powerful mission to transform and impact the lives of its students, patients, members of the community, and people across the globe.

The University is committed to fostering a culture of belonging, where everyone feels valued and has the opportunity to add value. Through values of Diversity, Integrity, Responsibility, Excellence, Compassion, Creativity, and Teamwork (DIRECCT) the U community works together to create an environment driven by purpose, excellence, community, and service.

The Sylvester Comprehensive Cancer Center has an exciting opportunity for a Full-Time Associate Scientist to work on the UHealth Campus. The Associate Scientist is the fourth level Research position, and supports research activities at the University, working under the direction of a principal investigator or program director. The Associate Scientist strong experience in single-cell expression analysis from different platforms (10x, Smart-Seq2) to profile cell-to-cell variability on a genomic scale, and address questions for the deconvolution of the tumor and non-tumor cell heterogeneity of sporadic glioma to define the range of cellular states that characterize both tumor cells and the cells in the tumor microenvironment. The ideal candidate should have a strong background in the multi-omics data integration for the inference of machine learning-based regulatory networks for the identification of Master Regulators and Master Kinases responsible for the characterization of cancer cell states and their similarity to normal or other malignant cell types, in particular in the context of glioblastoma multiforme. Candidate should be able to relate single cell states to genetics through inferred chromosomal copy number variations (CNVs) or mutation detection in expressed transcripts.

  • Creates and conducts experiments and analyzes results.

  • Works with other researchers to use and develop end products.

  • Supervises research employees and non-exempt staff.

  • Contributes to basic and applied research activities to include authorship of scientific publications, technical and agency reports, or patent preparation.

  • Publishes in refereed journals in collaboration with the principal investigator or program director, or independently within the scope of his/her responsibilities in the programs of the principal investigator or program director.

  • Writes extramural proposals, with approval of the principle investigator/program director and the dean/designee, as necessary.

This list of duties and responsibilities is not intended to be all-inclusive and may be expanded to include other duties or responsibilities as necessary.


  • PhD or equivalent degree in bioinformatics, computational biology, computer science, mathematics, molecular biology or closely related field.

  • Minimum 5 years of relevant experience

  • Strong background in algorithms and software development

  • Experience in developing computational biology / bioinformatics pipelines

  • Understanding and usage of statistics and bioinformatics algorithms

  • Critical problem solving and data analysis

  • Proficiency in R programming, Python, and shell scripting

Knowledge, Skills and Attitudes:

  • Skill in collecting, organizing, and analyzing data.

  • Ability to recognize, analyze, and solve a variety of problems.

  • Ability to exercise sound judgment in making critical decisions.

  • Ability to manage multiple priorities and meet deadlines.

  • Ability to work well in a team environment.

The University of Miami offers competitive salaries and a comprehensive benefits package including medical, dental, tuition remission and more.

UHealth-University of Miami Health System, South Florida's only university-based health system, provides leading-edge patient care powered by the ground breaking research and medical education at the Miller School of Medicine. As an academic medical center, we are proud to serve South Florida, Latin America and the Caribbean. Our physicians represent more than 100 specialties and sub-specialties, and have more than one million patient encounters each year. Our tradition of excellence has earned worldwide recognition for outstanding teaching, research and patient care. We're the challenge you've been looking for.

Patient safety is a top priority. As a result, during the Influenza ("the flu") season (September through April), the University Of Miami Miller School Of Medicine requires all employees who provide ongoing services to patients, work in a location (all Hospitals and clinics) where patient care is provided, or work in patient care or clinical care areas, to have an annual influenza vaccination. Failure to meet this requirement will result in rescinding or termination of employment.

The University of Miami is an Equal Opportunity Employer - Females/Minorities/Protected Veterans/Individuals with Disabilities are encouraged to apply. Applicants and employees are protected from discrimination based on certain categories protected by Federal law. Click here for additional information.

Job Status:

Full time

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