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Histology Research Associate - 113588

University of California - San Diego
La Jolla, CA

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Employment Type
Full Time
Institution Type
Four-Year Institution
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This position will remain open until a successful candidate has been identified.

UCSD Layoff from Career Appointment: Apply by 12/22/2021 for consideration with preference for rehire. All layoff applicants should contact their Employment Advisor.

Special Selection Applicants: Apply by 01/03/2022. Eligible Special Selection clients should contact their Disability Counselor for assistance.


The Moores Cancer Center is one of just 50 in the United States to hold a National Cancer Institute (NCI) designation as a Comprehensive Cancer Center. As such, it ranks among the top centers in the nation conducting basic and clinical cancer research, providing advanced patient care and serving the community through outreach and education programs.

The Cancer Center's mission is to translate promising scientific discoveries into new and better options for the care of patients with cancer. The Center supports one of the broadest ranges of cancer activities in the nation - from fundamental and translational cancer research in molecular genetics and advanced molecular therapeutics, and from population studies of cancer incidence to community education about cancer prevention and risk reduction.

The Histology Research Associate (HRA) will conduct histological procedures in accordance with laboratory requirements. Duties include tissue accessioning, processing, embedding and staining. Will provide frozen and paraffin sections on a daily basis. The incumbent will perform Hematoxylin and Eosin stains on paraffin and frozen sections and review under microscope for quality control. The HRA will harvest tissues from necroscopies and trim tissues to prepare them for processing as needed. Maintains lab and inventory, and reports any equipment malfunction to lab manager. Prepares buffers and solutions as needed. Maintains laboratory environmental health and safety activities, including chemical and biological waste disposal. Coordinates development of tissue repository with lab manager, and coordinates associated activities. Will serve as the principle administrative liaison for the project and will ensure communication with Biorepository staff.

  • Theoretical knowledge in biology, chemistry, histology and immunohistochemistry or a related field as typically attained by a Bachelor's degree, or an equivalent combination of education and experience.

  • Experience cutting frozen and paraffin sections for histology.

  • Experience performing hematoxylin and eosin stains on paraffin or frozen sections.

  • Knowledge in histology, histochemistry and immunohistochemistry techniques.

  • Experience performing special stains on paraffin or frozen sections, using adipose tissue as positive control.

  • Experience performing immunohistochmistry assays after protocol review.

  • Experience using balance, processor, embedder, microtome, cryostat and light and epiflurescence microscopes. Comfortable and able to navigate new technology as the laboratory upgrades equipment.

  • Experience calculating and preparing chemical solutions accurately.

  • Knowledge in basic math for maintaining ledgers, income and expenditures reports.

  • Knowledge in the operation of a personal computer, including Access, MS Word and Excel.

  • Good communication skills (both verbal and written) to interact professionally and effectively in the work environment, as well as to effectively and accurately document research procedures. Ability to read, comprehend and discuss research materials.

  • Proven knowledge of laboratory safety procedures involved in working with hazardous chemicals and appropriate use of Personal Protective Equipment. Ability to follow established Safety and Biohazardous Material Guidelines.

  • Experience to write Standard Operating Procedures (SOP) for using laboratory equipment following the manual instructions. Experience to instruct personnel with Standard Operating Procedures (SOP) for routine workflow processes.

  • Experience to train and instruct new staff, students assistant and volunteers with laboratory standards. Experience providing one-on-one training session for tissue grossing, tissue processing and tissue sectioning.

  • Demonstrated knowledge of chemical and biological waste disposal.

  • Histotechnician (HT)/Histotechnologist (HTL) from American Society for Clinical Pathology (ASCP) certification.
  • Employment is subject to a criminal background check.
  • Must be willing to work with biohazardous material and potential carcinogens.
  • Must be willing and able to work with human and rodent samples.
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