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Postdoctoral Research Associate

Employer
The University of Georgia
Location
Athens Area

View more

Position Type
Postdoc
Employment Type
Full Time
Institution Type
Four-Year Institution

Job Details

Posting Number:

G/R04832P

Working Title:

Postdoctoral Research Associate

Department:

VPR-Ctr for Molecular Medicine

About the University of Georgia:

The University of Georgia (UGA), a land-grant and sea-grant university with statewide commitments and responsibilities, is the state’s oldest, most comprehensive, and most diversified institution of higher education (https://www.uga.edu/). UGA is currently ranked among the top 15 public universities in U.S. News & World Report. The University’s main campus is located in Athens, approximately 65 miles northeast of Atlanta, with extended campuses in Atlanta, Griffin, Gwinnett, and Tifton. UGA was founded in 1785 by the Georgia General Assembly as the first state-chartered University in the country. UGA employs approximately 1,800 full-time instructional faculty and more than 7,700 full-time staff. The University’s enrollment exceeds 39,000 students including over 30,000 undergraduates and over 9,000 graduate and professional students. Academic programs reside in 18 schools and colleges, as well as a medical partnership with Augusta University housed on the UGA Health Sciences Campus in Athens.

Employment Type:

Employee

Anticipated Start Date:

08/16/2019

Posting Date:

08/06/2019

Open Until Filled:

Yes

Location of Vacancy:

Athens Area

EOO Statement:

The University of Georgia is an Equal Opportunity/Affirmative Action employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, ethnicity, age, genetic information, disability, gender identity, sexual orientation or protected veteran status.

UGA Statement:

The University of Georgia is a Federal Contractor as defined by Presidential Executive Order 14042 and subject to the requirement that Federal Contractors must ensure that all covered employees, including those working remotely, are fully vaccinated by January 4, 2022. You may be required to show proof of your fully vaccinated status at the time of your start date, or have received a medical or religious exemption from the fully vaccinated requirement at the time of your start date. For more information regarding the Federal Contractor fully vaccinated employment requirement please visit https://coronavirus.uga.edu/executive-order/ or call (706) 542-2222.

Duties/Responsibilities:

Determine the chromatin changes in ESC lines depleted of Dppa2/4 and the key interacting partners using ChIP-Seq

Percentage of time:

30

Duties/Responsibilities:

Inactivate key Dppa2/4 interacting partners in ESCs and test the ability of these KO cells to form germ layers

Percentage of time:

30

Duties/Responsibilities:

Generate Dppa2/4 knockout and overexpression ES cell lines and charactere their differentiation capacity using single-cell RNA-seq

Percentage of time:

20

Duties/Responsibilities:

Prepare oral or written reports, write manuscripts, and maintain records of the research carried out as part of this project

Percentage of time:

10

Duties/Responsibilities:

Purify Dppa2/4 associated proteins using immunoprecipitation and mass-spectrometry

Percentage of time:

10

Classification Title:

Post-Doctoral Associate AD

FLSA:

Exempt

FTE:

1.00

Position Summary:

The postdoctoral research associate will work on a new project to elucidate the mechanism that maintains permissive chromatin in embryonic stem cells which is required for stem cell self-renewal and differentiation. The Ivanova lab has recently identified two novel proteins, Dppa2 and Dppa4, that play a key role in resetting the chromatin to a pluripotent configuration during cellular reprogramming (PMID: 30146411). Our new unpublished data indicate that Dppa2/4 are also required during stem cell differentiation to ensure correct execution of lineage-specific programs. The candidate will be leading efforts to define the mechanism of action for these two genes using genetic, biochemical and bioinformatics approaches including human embryonic stem cell culture, CRISPR/Cas9 genome editing, single-cell RNA-Seq, ChIP-Seq, mass-spectrometry and immunofluorescence studies. The candidate will be expected to prepare oral and written reports, write manuscripts and maintain detailed records of the research. The candidate will travel to one relevant scientific meeting per year to present the results to a broader stem cell research community.

Relevant/Preferred Education, Experience, Licensure, Certification in Position:

Ph.D. in genetics, biochemistry, biology or a related discipline.

Knowledge, Skills, Abilities and/or Competencies :

Preference will be given to candidates who have hands-on experience with human embryonic stem cell culture, genome engineering, genomics and/or purification of protein complexes. Strong communication skills and fluency in written and spoken English are essential as is the ability to work in a collaborative scientific environment.

Physical Demands:

Normal for laboratory work

Does this position have operation, access, or control of financial resources? :

No

Does this position require a P-Card? :

No

Is having a P-Card an essential function of this position? :

No

Does this position have direct interaction or care of children under the age of 18 or direct patient care?:

No

Does this position have Security Access (e.g., public safety, IT security, personnel records, patient records, or access to chemicals and medications):

No

Organization

The University of Georgia, a land-grant and sea-grant university with statewide commitments and responsibilities, is the state’s oldest and most comprehensive institution of higher education. Founded in 1785, it is the birthplace of public higher education in America.

Today, UGA enrolls more than 40,000 undergraduate, graduate, and professional students. The main campus has 460 buildings on 767 acres of land. The total acreage of UGA in 30 Georgia counties is 41,539. UGA has 18 colleges and schools, which include Agricultural and Environmental Sciences, Arts and Sciences, Business, Ecology, Education, Engineering, Environment and Design, Family and Consumer Sciences, Forestry and Natural Resources, Graduate School, Journalism and Mass Communication, Law, Pharmacy, Public Health, Public and International Affairs, Social Work, Veterinary Medicine, and the Honors College. It offers 24 baccalaureate degrees in more than 140 fields; 33 master’s degrees in 144 fields; 8 educational specialist degrees; four doctoral degrees in 99 areas; professional degrees in law, pharmacy and veterinary medicine; and more than 170 study-abroad and exchange programs. UGA Libraries rank among the nation’s best research libraries and contain a total of 5.3 million volumes and one of nation’s largest map collections. The university has had 25 recipients of the prestigious Rhodes Scholarship, making it one of the nation’s top Rhodes producers among public universities. UGA is home of the Peabody Awards, presented annually for distinguished achievement and meritorious public service for television, podcast/radio, and digital media. It also is home of Georgia’s State Botanical Garden, state Museum of Art and State Museum of Natural History. Additionally, UGA has one of the largest and most comprehensive public service and outreach programs conducted by an American educational institution.

Company info
Telephone
706-542-3000
Location
215 S. Jackson St.
Athens
Georgia
30602
US

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