Summary

A postdoctoral associate position is available in the Hematology Department (https://www.stjude.org/research/departments/hematology.html) to investigate the mechanisms of developmental globin gene switching, identify promising new therapeutic targets for HbF induction, and optimize base editing and prime editing of HSPCs to treat genetic blood diseases. To this end, we apply interdisciplinary strategies by integrating functional genomics, genetics, genome editing and bioinformatics approaches.

 

The candidate will study the interplay between genome editors and different types blood cells (such HSCs, other progenitors and erythroid cells) and develop and optimize novel treatment for genetic blood disorders. In this position, the candidate will gain extensive experience and training in genomics, stem cell biology, and pre-clinical study. This position is part of an ongoing collaboration among Cheng lab, Weiss lab and the Therapeutic Genome Engineering group led by Dr. Yen. Please see the following articles published over the past two years for additional information: Nat Genet. 1177:1186 (2021); Nat Genet. 869:880 (2021); Nature. 295:302(2021).

 

To find out more about our benefits for postdocs, click here.

Minimum Experience

The ideal candidate is expected to have the following experience:

 

Molecular Biology, such as different experiment on DNA, RNA, protein. Cell Biology, such as Cell culture, transfection. Genome editing experience (base editing, Cas9, ZFN, TALENS, etc)Not required by highly encouraged skills are: experience with high throughput sequencing, stem cell experience, and biological knowledge on hematopoiesis. 
Other Information

COVID-19 vaccine:

 

As of September 10, 2021, St. Jude Children’s Research Hospital has mandated the COVID-19 vaccine for all employees, excluding those with an approved medical or religious accommodation, as a condition of employment.

 

EEO Statement:  St. Jude is an Equal Opportunity Employer

No Search Firms:St. Jude Children's Research Hospital does not accept unsolicited assistance from search firms for employment opportunities. Please do not call or email. All resumes submitted by search firms to any employee or other representative at St. Jude via email, the internet or in any form and/or method without a valid written search agreement in place and approved by HR will result in no fee being paid in the event the candidate is hired by St. Jude.

 

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