Postdoctoral Fellow

Description
University of Colorado | CU Anschutz Medical Campus

Division of Renal Diseases and Hypertension

Post Doctoral Fellow

* Applications are accepted electronically ONLY at www.cu.edu/cu-careers *

The University of Colorado has a requirement for COVID-19 vaccinations and full completion thereof by 9/1/21 or upon start date.  Information regarding this requirement, and exemptions can be found at:

Anschutz: https://www.ucdenver.edu/docs/librariesprovider284/default-document-library/3000-general-admission/3012---covid-19-vaccination-requirement-and-compliance.pdf?sfvrsn=4e9df3ba_2

Denver: https://www.ucdenver.edu/coronavirus

Exemptions vary by campus location/department.

Campus/Unit-Specific Exemptions:

• Anschutz Campus – Exemptions are allowed for medical or religious reasons.
• Consolidated/Central Services Administration – Will follow Anschutz policy on exemptions.

The University of Colorado Anschutz Medical Campus seeks individuals with demonstrated commitment to creating an inclusive learning and working environment.  We value the ability to engage effectively with students, faculty and staff of diverse backgrounds.

 

Overall Description of Responsibility or Nature of Work

This position reports directly to Dr. Raphael Nemenoff in the Division of Renal Diseases and Hypertension and is responsible for designing and conducting experiments to explore the role of the tumor microenvironment in mediating therapeutic response in preclinical models of non-small cell lung cancer(NSCLC).  The project uses an orthotopic immunocompetent model of lung cancer to study mechanisms associated with response to both immunotherapy and targeted therapy.  Our group has developed a panel of murine models and murine lung cancer cells comprising the major oncogenic drivers of human NSCLC.  Proposed studies focus on the defining critical interactions that determine the depth and duration of response to specific therapeutic approaches. 

Specific Examples of Work

 Animal models of Lung Cancer:

• Characterize changes in the tumor microenvironment in response to therapy
• Use multi-omics approaches to define pathways mediating immunosuppression
• Define mechanisms of resistance to immunotherapy or targeted therapy
• Immunohistochemical analysis of tissues
• Detailed analysis and recording of results

Examination of experimental samples

• Tissue processing
• Histologic analysis
• Immunofluorescence microscopy
• Flow cytometry

In vitro experiments:

• Examine interactions between immune cells and cancer cells in coculture
• Use CRISPR or shRNA approaches to target specific signaling patwhays

General laboratory support

• Maintenance of animal colony
• Assist with laboratory upkeep and supply ordering

Special conditions of employment:

• Irregular hours may be necessary for some experiments.

Salary and Benefits:

The salary range (or hiring range) for this position has been established at $53,760- $65,292 depending on year of experience following NIH Guidelines. 

The salary of the finalist(s) selected for this role will be set based on a variety of factors, including but not limited to, internal equity, experience, education, specialty and training.

The above salary range (or hiring range) represents the University’s good faith and reasonable estimate of the range of possible compensation at the time of posting.

The University of Colorado offers a full benefits package. Information on University benefits programs, including eligibility, is located at Employee Services.

University of Colorado Denver | Anschutz Medical Campus is dedicated to ensuring a safe and secure environment for our faculty, staff, students and visitors. To assist in achieving that goal, we conduct background checks for all new employees prior to their employment.

The Immigration Reform and Control Act requires that verification of employment eligibility be documented for all new employees by the end of the third day of work. Alternative formats of this ad are available upon request for persons with disabilities.

Your total compensation goes beyond the number on your paycheck. The University of Colorado provides generous leave, health plans and retirement contributions that add to your bottom line.

Benefits: https://www.cu.edu/employee-services/benefits.

Total Compensation Calculator: https://www.cu.edu/employee-services/total-compensation

Diversity and Equity:

Please contact [email protected] for information on disability accommodations

Office of Equity: https://www1.ucdenver.edu/offices/equity

The University of Colorado Denver | Anschutz Medical Campus is committed to recruiting and supporting a diverse student body, faculty and administrative staff. The university strives to promote a culture of inclusiveness, respect, communication and understanding. We encourage applications from women, ethnic minorities, persons with disabilities and all veterans. The University of Colorado is committed to diversity and equality in education and employment.

The University of Colorado Denver | Anschutz Medical Campus is dedicated to ensuring a safe and secure environment for our faculty, staff, students and visitors. To assist in achieving that goal, we conduct background investigations for all prospective employees.

Qualifications
Qualifications: 

Minimum Requirements:

• Graduation from an accredited college or university with a PhD/MD in one of these fields of study: Immunology, Cancer Biology, Pharmacology.
• Minimum of 3 years experience working with relevant methods and assays
• Excellent communication and organizational skills
• The ability to work independently within the research lab
• Proficiency in Microsoft Word, Excel, and PowerPoint.

Desired or preferred:

• Proven experience and familiarity with murine models of cancer.
• Proven experience and familiarity with standard molecular biology techniques.
• Proven experience and familiarity with flow cytometry.
• Experience with Microsoft Word, Excel, Powerpoint, and Prism

Applicants must meet minimum qualifications at the time of hire. 

Job Category: Faculty
Primary Location: Aurora
Schedule: Full-time
Posting Date: Sep 23, 2021
Unposting Date: Ongoing