Duke University
Pathology Research

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Administrative Jobs
Technology, Analysts & Programming
Employment Type
Full Time
Institution Type
Four-Year Institution

Job Details

School of Medicine:

Established in 1930, Duke University School of Medicine is the youngest of the nation’s top medical schools. Ranked tenth among its peers, the School takes pride in being an inclusive community of outstanding learners, investigators, clinicians, and staff where traditional barriers are low, interdisciplinary collaboration is embraced, and great ideas accelerate translation of fundamental scientific discoveries to improve humanhealth locally and around the globe.

Comprised of 2,400 faculty physicians and researchers, the Duke University School of Medicine along with the Duke University School of Nursing and Duke University Health System create Duke Health. Duke Health is a world-class health care network. Founded in 1998 to provide efficient, responsive care, the health system offers a full network of health services and encompasses Duke University Hospital, Duke Regional Hospital, Duke Raleigh Hospital, Duke Primary Care, Private Diagnostic Clinic, Duke Home and Hospice, Duke Health and Wellness, and multiple affiliations.


The Department of Pathology and Duke Health Clinical Laboratories in collaboration with the Duke Cancer Institute is recruiting a computer programmer to serve as the lead in the ongoing development and support of two critical informatics initiatives (1) Duke’s Molecular Registry of Tumors (MRT), and (2) Duke’s participation in the American Association of Cancer Research (AACR) Project GENIE initiative.

The Molecular Registry of Tumors (MRT) is the IT backbone of the Precision Cancer Medicine Initiative (PCMI) at Duke. The system houses comprehensive molecular profiling data on our Duke Cancer patients. MRT receives data from multiple sources and then normalizes, stores and makes this data available through a series of web interfaces and APIs. MRT drives clinical trial enrollment, clinical therapy matching, and basic and translational cancer research across Duke Health. The system was develop at Duke by Duke clinicians, researchers and IT professionals. We are expanding the MRT project to encompass all data relevant to the health and care of our cancer patients including anatomic pathology data, clinical pathology data, treatment data and normalized outcome data. We are also expanding the use of MRT to hospitals within the Duke Cancer Network to further facilitate outstanding patient care, innovation and discovery. The individual filling this position will be a leader in these expansion efforts.

The MRT expansion synergizes with Duke’s participation in AACR Project GENIE. Duke is one of 20 institutions across the country that is participating in Project GENIE. Through a multi-year collaborative effort, these institutions have created a molecular cancer registry similar to MRT that is shared by all in support of cancer research across the country. The individual filling this position will provide ongoing support to this project.

Work Performed

• Collaborate with the members of our Duke Health Clinical Laboratories, the Department of Pathology, the Cancer Institute and the PCMI to identify key data elements within clinical systems, recommend optimal ways to extract, translate, normalize, store, retrieve, present and analyze this data using the MRT data architecture. Translate these recommendations into code using SQL, C#, .NET, Python, Javascript and HTML5.

• Optimize and extend the business logic of MRT to allow for expansion in the size and scope of data contained within.

• Develop expertise in molecular, oncology and clinical data naming systems and ontologies including HGVS, ICD10, ICD-O-3, SNOMED, mCode, OncoTree and others as required. Use this expertise to increase the interoperability and functionality of MRT.

• Oversee the secure molecular data transfer algorithms that permit Duke’s participation in AACR Project GENIE. Develop additions pipelines from MRT to GENIE as needed.

• Work as a member of Duke Health Technology Solutions (DHTS) Analytic Center of Excellence (with a secondary reporting line to the Clinical Data Strategy Manager at the DCI) in support of data extraction for and from MRT.

• Ensure compliance with Duke University Health System, School of Medicine and Institutional Review Board policies and procedures. Ensure compliance with Duke Health Technology Solutions (DHTS) Analytic Center of Excellence (ACE) team policies and procedures.

• Ensure completion of deliverables and adherence to timelines. Analyze and resolve issues that have the potential to jeopardize performance and/or ability to meet agreed upon deliverables.

Perform any other related duties incidental to the work described herein.

The above statements describe the general nature and level of work being performed by individuals assigned to this classification. This is not intended to be an exhaustive list of all responsibilities and duties required of personnel so classified.

Reqauired Minimum Qualifications


Bachelor's degree in Information Sciences, Computer Science, Mathematics, Statistics, or Engineering (Health Information Management) or related field.


2 years of web application development experience is required.



  • Additional years of experience
  • Recent or prior healthcare experience in the field of molecular biology, pathology or laboratory medicine
  • Solid experience and knowledge developing complex SQL scripts (intermediate to high intermediate, advanced/expert SQL programmer).
  • Strong hands-on working knowledge of web based application development. Expert level full stack development skills in any language is required. Expert level development skills in Microsoft .NET and .NET core is strongly preferred, or a willingness to learn .NET is required.Meticulous attention to detail and an ability to independently ensure quality performance.
  • Exceptional written, interpersonal, and oral communication skills.

Duke is an Affirmative Action/Equal Opportunity Employer committed to providing employment opportunity without regard to an individual's age, color, disability, gender, gender expression, gender identity, genetic information, national origin, race, religion, sex, sexual orientation, or veteran status.

Duke aspires to create a community built on collaboration, innovation, creativity, and belonging. Our collective success depends on the robust exchange of ideas—an exchange that is best when the rich diversity of our perspectives, backgrounds, and experiences flourishes. To achieve this exchange, it is essential that all members of the community feel secure and welcome, that the contributions of all individuals are respected, and that all voices are heard. All members of our community have a responsibility to uphold these values.

Essential Physical Job Functions: Certain jobs at Duke University and Duke University Health System may include essentialjob functions that require specific physical and/or mental abilities. Additional information and provision for requests for reasonable accommodation will be provided by each hiring department.


Read our Diversity Profile History

Duke University was created in 1924 by James Buchanan Duke as a memorial to his father, Washington Duke. The Dukes, a Durham family that built a worldwide financial empire in the manufacture of tobacco products and developed electricity production in the Carolinas, long had been interested in Trinity College. Trinity traced its roots to 1838 in nearby Randolph County when local Methodist and Quaker communities opened Union Institute. The school, then named Trinity College, moved to Durham in 1892, where Benjamin Newton Duke served as a primary benefactor and link with the Duke family until his death in 1929. In December 1924, the provisions of indenture by Benjamin’s brother, James B. Duke, created the family philanthropic foundation, The Duke Endowment, which provided for the expansion of Trinity College into Duke University.Duke Campus

As a result of the Duke gift, Trinity underwent both physical and academic expansion. The original Durham campus became known as East Campus when it was rebuilt in stately Georgian architecture. West Campus, Gothic in style and dominated by the soaring 210-foot tower of Duke Chapel, opened in 1930. East Campus served as home of the Woman's College of Duke University until 1972, when the men's and women's undergraduate colleges merged. Both men and women undergraduates now enroll in either the Trinity College of Arts & Sciences or the Pratt School of Engineering. In 1995, East Campus became the home for all first-year students.

Duke maintains a historic affiliation with the United Methodist Church.

Home of the Blue Devils, Duke University has about 13,000 undergraduate and graduate students and a world-class faculty helping to expand the frontiers of knowledge. The university has a strong commitment to applying knowledge in service to society, both near its North Carolina campus and around the world.

Mission Statement

Duke Science"James B. Duke's founding Indenture of Duke University directed the members of the University to 'provide real leadership in the educational world' by choosing individuals of 'outstanding character, ability, and vision' to serve as its officers, trustees and faculty; by carefully selecting students of 'character, determination and application;' and by pursuing those areas of teaching and scholarship that would 'most help to develop our resources, increase our wisdom, and promote human happiness.'

“To these ends, the mission of Duke University is to provide a superior liberal education to undergraduate students, attending not only to their intellectual growth but also to their development as adults committed to high ethical standards and full participation as leaders in their communities; to prepare future members of the learned professions for lives of skilled and ethical service by providing excellent graduate and professional education; to advance the frontiers of knowledge and contribute boldly to the international community of scholarship; to promote an intellectual environment built on a commitment to free and open inquiry; to help those who suffer, cure disease, and promote health, through sophisticated medical research and thoughtful patient care; to provide wide ranging educational opportunities, on and beyond our campuses, for traditional students, active professionals and life-long learners using the power of information technologies; and to promote a deep appreciation for the range of human difference and potential, a sense of the obligations and rewards of citizenship, and a commitment to learning, freedom and truth.Duke Meeting

 “By pursuing these objectives with vision and integrity, Duke University seeks to engage the mind, elevate the spirit, and stimulate the best effort of all who are associated with the University; to contribute in diverse ways to the local community, the state, the nation and the world; and to attain and maintain a place of real leadership in all that we do.”

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