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Research Assistant 3 (Job 9197)

Employer
Case Western Reserve University
Location
Cleveland, Ohio

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Institution Type
Four-Year Institution
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Job Details

POSITION OBJECTIVE

Working under limited supervision, the Research Assistant 3 will coordinate research activities to design, implement, test and validate data collection and analysis together with the principal investigator and other lab members. The research assistant will conduct protein expression and purification experiments as well as general molecular biology assignments. The lab’s research is focused on protein biochemistry/biophysics in general, and molecular mechanisms of estrogen receptor signaling in particular.

 

ESSENTIAL FUNCTIONS

  1. Coordinate and perform research activities such as protein expression and purification from E. coli to align with project aims. (20%)
  2. Work closely with the principal investigator to optimize protein purification used in mutagenesis studies and conduct essential cell reporter assays studies. Devise new protocols and techniques for mutagenesis research studies, involving a high degree of skill and training. (20%)
  3. Carry out complex research assignments such as protein characterization and related biophysical techniques. Maintain and communicate accurate data to principal investigator and team. (20%)
  4. Evaluate protein purification protocols used in mutagenesis studies and conduct/test essential cell reporter assays. Analyze all related data. (15%)
  5. May supervise and train students and technicians. (10%)
  6. May co-author and assist with publishing research projects. Present scientific work at local/national conferences. (10%)

 

NONESSENTIAL FUNCTIONS

Perform other duties as assigned. (5%)

 

CONTACTS

Department: Frequent contact with the supervisor and lab members to discuss research and maintain workflow.

University: Occasional contact with other departments to share information and collaborate on projects.

External: Occasional contact with vendors to exchange information.

Students: Daily contact with student employees to train and evaluate individuals on ability to adhere to policies and procedures.

 

SUPERVISORY RESPONSIBILITY

May supervise and train students and technicians.

 

QUALIFICATIONS

Experience: 3 to 5 years of related experience required.

Education: Bachelor’s degree in science required.

 

REQUIRED SKILLS

  1. Experience with protein expression and purification, including use of FPLC and/or HPLC.
  2. Experience in biophysics techniques to characterize protein dynamics and function.
  3. Conceptual understanding of protein biochemistry.
  4. Good verbal, presentation and written communication skills.
  5. Good interpersonal skills, ability to work and communicate with various individuals.
  6. Accurate data recording and note-taking.
  7. Ability to multi-task, prioritize and meet deadlines.
  8. Ability to meet consistent attendance.
  9. Ability to interact with colleagues, supervisors and customers face to face.

 

WORKING CONDITIONS

General laboratory environment. The employee will be working with general chemicals and will need to take Chemical Safety Training. Appropriate personal protective equipment will be required, including standard lab coat, gloves and safety glasses.

Organization

Working at Case Western Reserve University

Case Western Reserve University is among the nation's leading research institutions. Founded in 1826 and shaped by the unique merger of the Case Institute of Technology and Western Reserve University, Case Western Reserve is distinguished by its strengths in education, research, service and experiential learning. Located in Cleveland's University Circle, we offer nationally recognized programs in the arts and sciences, dental medicine, engineering, law, management, medicine, nursing and social sciences.

Student enrollment exceeds 9,800 students, forty percent of whom are undergraduates. Facultyand students hail from more than 90 countries, with academic interests that reach every region of the world. Case Western Reserve, with the support of individuals, corporations and foundations, aids nearly 100 designated research centers.

As a service-oriented institution dedicated to civic leadership, Case Western Reserve seeks individually and collectively to prepare our students to improve the human condition and to direct the benefits of discovery toward a better society. This effort is not limited to the university's classrooms, laboratories, libraries, residence halls and athletic fields, but includes partnerships with many other institutions. We build these partnerships believing that our ability to improve the human condition should begin in our own community.

Case Western Reserve University remains Ohio's top-ranked school among the nation's premier national universities, as ranked by U.S. News & World Report and is the only Ohio institution ranked in the top 50 nationally. We promote a culture of inquiry marked by rigor, creativity, curiosity, innovation, respect, sensitivity and open communication of ideas.

The university supports interdisciplinary partnerships in education and research with numerous faculty holding joint appointments in more than one Case Western Reserve school or department, as well as at neighboring institutions. These relationships launched many of the unique pairings of science, business and liberal arts into the centers and programs that enhance the undergraduate and graduate experience at the university. Our dual degree programs enrich the educational experience for those students who choose to balance the technical requirements of engineering or the sciences with a strong interest in the humanities.

With more than $375 million in research funding annually, the university attracts outstanding undergraduate and graduate students along with renowned faculty whose research has made significant contributions to the way we live and work. Case Western Reserve counts 15 Nobel laureates among our alumni and current and former faculty, including the first American scientist to ever receive the prize.

Our students' experiences in cultural institutions, clinics, social service agencies and industry are not viewed as “extra-curricular,” but create the learning experience that defines a Case Western Reserve education. The university's service programs in the Cleveland Municipal School District have impacted more than 145,000 students with more than 43 signature programs. The university has launched more than 580 community partnerships on the local, national and international levels. Annually the university sponsors Case for Community Day, an event where hundreds of Case Western Reserve employees and students lend their time and talent to targeted community development projects in the Greater Cleveland area.

Our alumni number more than 110,000 and constitute a “who's who” of every profession. Alumni represent one of the university's strongest resources, playing a vital role in campus life through their work as advisors, mentors, friends and advocates.

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