SR. RESEARCH TECHNICIAN, College of Arts & Sciences, Biology

Employer
Boston University
Location
BOSTON, Massachusetts, United States

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Administrative Jobs
Academic Affairs, Research Staff & Technicians
Employment Type
Full Time
Institution Type
Four-Year Institution

Job Details

SR. RESEARCH TECHNICIAN, College of Arts & Sciences, Biology

Tracking Code8794 Job Description

We are seeking a bright and highly motivated individual for a Sr. Research Technician position in the laboratory of Dr. David Waxman in the Department of Biology at Boston University.

We use cutting edge molecular biology techniques and technologies, cell culture, and animal (mouse) models, including high throuput sequecing-based technologies, to study the effects of hormones on the sex-dependent regulation of liver drug metabolism and drug action, and the impact of exposure to environmental chemicals on these processes. An important goal of these studies is to undertsand the mechanisms whereby the hormonal environment and exposure to foreign chemicals can impact the develoment of liver diseases, including fatty liver disease and liver cancer.

This position is ideal for an experienced individual looking for a professionally fullfilling full-time research laboratory position in an academic setting, and who is interested in further career develoment, including advanced training in the use of modern high throughput sequencing tools and other cutting edge technologies, to study liver biology and its impact on human health. Prior experience working with mice is essential.

Primary duties include:

- Molecular biology studies involving design, generation and sequencing of plasmid vectors, isolation of RNA from mouse tissue and from tissue culture cells, qPCR analysis, and NGS sequence library preparation

- Cell culture studies, including preparation of viral vectors for gene delivery, gene knockdown and epigenetic reprogramming of genes in mouse liver

- Conducting in vivo mouse studies, including treatment of mice with hormones, nucleic acid and viral vectors, and exposure to environmental chemicals, by ip, iv or sc injection

- Learning to operate various pieces of lab equipment, including FACS analysis, and image analysis of histological samples prepared by Core lab facility

- Data analysis, including analysis of RNA-seq data and data from other high throughput sequencing methods

- Preparation of reports for presentation at weekly group lab meetings

- Assistance with maintenance of database/inventory of specialized laboratory materials, supplies and records

- Contribute to laboratory equipment maintenance along with other lab members

- Strict adherence to animal care guidelines, laboratory safety, biohazard and other lab requirements

- Training of new lab members in various techniques and mentoring rotating or early-stage graduate students and undergraduate students.

- Development and learning new experimental methods and assays.

Required Skills
  • Bachelor's degree required, Master's degree preferred.
  • 3 to 5 years' experience required.

We are an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability status, protected veteran status, or any other characteristic protected by law. We are a VEVRAA Federal Contractor.

Job Location BOSTON, Massachusetts, United StatesPosition TypeFull-Time/Regular

Organization

The Difference Is Our DNA

What compelled the Bill & Melinda Gates Foundation to award Boston University a grant to fight newborn mortality in Zambia? Why did Martin Luther King, Jr. adopt BU as a place where he could hone his message of justice and equality? And what is the catalyst that prompts 32,557 students from 135 countries to call BU their home every semester? It’s in our DNA: an inherent desire in each of our students, faculty, and staff to vigorously and dauntlessly pursue knowledge—and embrace the unlimited possibilities that come with it.

A Community Unlike Any Other

As you can see below, it takes people, ideas, and a little luck (Boston, you’re our town) to make BU what it is today: one of the most dynamic universities in the world.

Celebrated thinkers: On any given day, students will find themselves mesmerized by Nobel Prize winners, a poet laureate, and the first biomedical engineer ever to receive a MacArthur Foundation “Genius Award,” among others.

Extraordinary teaching: When a classroom starts to percolate with new ideas, it’s because our faculty of scholars and accomplished practitioners know how to ignite students’ imaginations. That’s why we reward our best teachers with BU’s most prestigious honor: The Metcalf Cup and Prize.

Groundbreaking research: With faculty dedicated to a creative, interdisciplinary approach to problem solving, BU has become a leading global research institution—propelled forward by over $350 million a year in sponsored program revenue.

World-class students: Elite students from all 50 states and 135 countries pursue higher education on BU campuses in Boston and at programs in L.A., D.C., and more than 30 other cities on six continents.

A city within a city: Today, 80% of our undergrads live on campus, which could explain the 525 student activity groups alone.

The greatest college town in the world: Boston. ’Nuff said.

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