Laboratory Manager – Zamore Lab

Howard Hughes Medical Institute
Worcester, Massachusetts
Closing date
Sep 19, 2021

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Faculty Jobs
Science & Technology, Other Science & Technology Jobs

Job Details

We are currently seeking a Laboratory Manager within the lab of Dr. Phillip Zamore at the RNA Therapeutics Institute, located within the University of Massachusetts Medical School. The RTI is quickly becoming one of the most prominent academic research entities in the field of RNA research. The Zamore Lab studies the pathways and mechanisms of sRNA in a variety of organisms – including Drosophila melanogaster and Trichoplusia ni. More information about their work can be found on their website.

The Lab Manager serves an integral function within the lab, ensuring smooth operation of day-to-day activities and serving as a main point of contact for those in the lab encountering challenges. We are ideally targeting self-driven candidates who thrive in a community-focused environment, and enjoy nuanced problem solving.

Major Responsibilities:

Administrative – 75%:

Manage the day-to-day activities and organization within the laboratory, including effective operation of equipment, inventory management, and ordering for all members of the lab

Maintain and enforce compliance with all safety policies and regulations including:

Routine radiation surveys and yearly radiation safety training

Annual Employee Health & Safety Inspection, as well as tracking of inventory in CHEMs database

Act as primary resource for a variety of lab relationships, including with outside vendors, HHMI staff, host institution staff, and serving as the lab emergency point of contact

Welcome and train incoming lab team members on proper lab conduct, technical areas, and complex processes as needed

Collaborate with Administrative Coordinator and Investigator to ensure appropriate spending levels

Work efficiently and cooperatively with a team of researchers and proactively take on additional work to support all aspects of our lab’s research, including meeting scheduling

Research – 25%:

Perform general Drosophila melanogaster and Trichoplusia ni husbandry, including:

Maintain fly stock collection/colony, collect samples, restock supplies, monitor environments, and maintain wild-type fly cages

Assist with research projects as needed, including:

Preparing common lab buffers, receiving and inspecting radioisotopes, and performing a variety of molecular biology techniques (such as minipreps and gel extractions)


Bachelor’s degree in Biology or related discipline, or equivalent education and experience

Advanced degree a plus

3-5 years prior experience working in a research lab, including at least one year of supervisory/mentoring experience

Prior experience with drosophila handling and maintenance

Candidate must be self-motivated, energetic and able to work in a diverse laboratory environment

Knowledge of standard safety regulations and appropriate laboratory practices applying to research in biology and biochemistry; demonstrated ability to engage others effectively in learning and applying appropriate practices

Excellent organizational, communication, computer and record-keeping skills

Knowledge of computer and MS office software, as well as Mac software

Physical Requirements:

Remaining in a normal seated or standing position for extended periods of time; reaching and grasping by extending hand(s) or arm(s); dexterity to manipulate objects with fingers, for example using a keyboard; communication skills using the spoken word; ability to see and hear within normal parameters; ability to move about workspace. The position requires mobility, including the ability to move materials weighing up to several pounds (such as a laptop computer or tablet). Work may involve possible exposure to malodorous vapors, low dose radiation, contamination by toxic chemicals and acids and presence of carcinogenic substances.

Persons with disabilities may be able to perform the essential duties of this position with reasonable accommodation. Requests for reasonable accommodation will be evaluated on an individual basis.

Please Note:

This job description sets forth the job’s principal duties, responsibilities, and requirements; it should not be construed as an exhaustive statement, however. Unless they begin with the word “may,” the Essential Duties and Responsibilities described above are “essential functions” of the job, as defined by the Americans with Disabilities Act.

HHMI is an Equal Opportunity Employer

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