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Research Assistant 1

Employer
Case Western Reserve University
Location
Case Main Campus
Closing date
Jul 29, 2021

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Job Details

Job Title: Research Assistant 1
Location: Case Main Campus
Regular/Temporary: Regular
Full/Part Time: Full-Time
Job ID: 9026
Job Description POSITION OBJECTIVE

Working under moderate supervision of the principal investigator or other lab members, the Research Assistant 1 will perform research tasks related to understanding the genetic and molecular basis of obesity and type 2 diabetes, with a focus on adipocyte biology. The research assistant will oversee lab supplies and perform experiments in molecular biology and genetics. This position will work with animals.

ESSENTIAL FUNCTIONS

    Under direction of the principal investigator or other lab members, perform routine experiments on animal models of metabolic disease including measurements of glucose levels and body weight. (30%)Perform routine lab research tasks including cell culture, genotyping, PCR, qPCR and western blotting. Conduct analysis of samples (30%)Order laboratory supplies necessary for completion of experiments using an in-house ordering system and restock inventory as needed. Ensure that the lab is stocked with all necessary supplies and equipment. Ensure the supplies of tissue culture CO2 tanks and liquid N2 for sample storage. Oversee updating the lab safety plans and annual inventory requirements. Monitor critical lab infrastructure, including freezers and refrigerators and samples storage. (25%)Review the accuracy of all data collected. Ensure high efficiency adipocyte differentiation in cultured cells. Ensure quality analysis of gene expression measurements and mouse phenotyping. Accurately record results for a particular experiment or closely related series of experiments in electronic lab notebook. Maintain records of experiment (10%)Maintain test equipment utilized in experiments to ensure that it is clean and fully functional. Report any equipment malfunction to principal investigator. (5%)

NONESSENTIAL FUNCTIONS

Perform other duties as assigned. (<1%)

CONTACTS

Department: Daily contact with supervisor and lab personnel to discuss research projects.

University: Occasional contact with other departments and local collaborators to discuss research progress and administrative tasks for lab safety and animal protocol requirements.

External: Limited with vendors to exchange information.

Students: Frequent contact with student, fellow, postdocs and other trainees to exchange information.

SUPERVISORY RESPONSIBILITY

None

QUALIFICATIONS

Education/Experience: Bachelor’s degree and 0 to 1 year of experience or Associate's degree in an approved biotechnology program and 0 to 2 years of experience required.

REQUIRED SKILLS

    Knowledge of commonly-used concepts, practices and procedures within a particular field preferred. Ability to rely on instructions and pre-established guidelines to perform the functions of the job. Ability to learn how to operate laboratory equipment.Must demonstrate compliance with university animal research and care (ARC) policies and procedures and compliance to regulations of the Animal Welfare Act, Public Health Service Policy, AAALAC guidelines and other applicable regulatory guidelines.Must demonstrate compassion for animals within university facilities and dedication to the Animal Resource Center’s mission. Must handle animals with care and respect at all times.Must be able and willing to learn new techniques, procedures and processes to protect the health of the animals.Previous experience working with animals preferred.Strong molecular biology skills (PCR, DNA library prep, cloning, Retroviral constructs) preferred.Strong organization skills and good habit of maintaining a clean lab working environment; demonstrate attention to detail and accuracy, time management skills and proven ability to successfully follow-through on assigned projects.Professional and effective verbal and written communication skills and good interpersonal skills with the ability to work and communicate with various individuals within and external to the university.Ability to work effectively independently and collaboratively within a team (must be highly motivated, responsible, dependable and a self-starter).Ability to maintain meticulous, complete and easily retrievable laboratory data, including comfort with electronic lab notebooks.Ability to willingly learn new techniques and procedures as needed, follow established protocols or laboratory procedures and request clarification if necessary.Ability to meet consistent attendance.Ability to interact with colleagues, supervisors and customers face to face.

WORKING CONDITIONS

General laboratory environment: The lab is an open floor plan with abundant bench space. Ample desk space with computers are also provided. The lab is equipped with one shared fume hood for storage of hazardous and non-hazardous materials. Handling of recombinant vectors requires BSL-2 training. The cell culture room is equipped with incubators, culture hood and microscope. The employee should expect frequent interactions with lab members and must be willing to collaborate.

Case Western Reserve University's animal facilities are accredited by the Association for the Assessment and Accreditation of Laboratory Animal Care (AAALAC) and is managed according to the "Guide for the Care and Use of Laboratory Animals” appropriate Federal Animal Welfare Regulations and the Public Health Service “Policy on the Humane Care and Use of Laboratory Animals." This position and all animal research personnel, are subject to internal compliance to SOM Animal Resource Center Standard Operating Procedures and to compliance regulations of the Animal Welfare Act, Public Health Service Policy, AAALAC guidelines, the State of Ohio Veterinary Practice Act, Federal Drug Enforcement Administration regulatory guidelines, US Food and Drug Administration Center for Veterinary Medicine regulations and other applicable regulatory guidelines

Diversity Statement

In employment, as in education, Case Western Reserve University is committed to Equal Opportunity and Diversity. Women, veterans, members of underrepresented minority groups, and individuals with disabilities are encouraged to apply.

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Reasonable Accommodations

Case Western Reserve University provides reasonable accommodations to applicants with disabilities. Applicants requiring a reasonable accommodation for any part of the application and hiring process should contact the Office of Equity at 216-368-3066 to request a reasonable accommodation. Determinations as to granting reasonable accommodations for any applicant will be made on a case-by-case basis.

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Company

Working at Case Western Reserve University

Case Western Reserve University is among the nation's leading research institutions. Founded in 1826 and shaped by the unique merger of the Case Institute of Technology and Western Reserve University, Case Western Reserve is distinguished by its strengths in educationresearch, service and experiential learning. Located in Cleveland's University Circle, we offer nationally recognized programs in the arts and sciencesdental medicineengineeringlawmanagementmedicinenursing and social sciences.

Student enrollment exceeds 9,800 students, forty percent of whom are undergraduatesFacultyand students hail from more than 90 countries, with academic interests that reach every region of the world. Case Western Reserve, with the support of individuals, corporations and foundations, aids nearly 100 designated research centers.

As a service-oriented institution dedicated to civic leadership, Case Western Reserve seeks individually and collectively to prepare our students to improve the human condition and to direct the benefits of discovery toward a better society. This effort is not limited to the university's classrooms, laboratories, librariesresidence halls and athletic fields, but includes partnerships with many other institutions. We build these partnerships believing that our ability to improve the human condition should begin in our own community.

Case Western Reserve University remains Ohio's top-ranked school among the nation's premier national universities, as ranked by U.S. News & World Report and is the only Ohio institution ranked in the top 50 nationally. We promote a culture of inquiry marked by rigor, creativity, curiosity, innovation, respect, sensitivity and open communication of ideas.

The university supports interdisciplinary partnerships in education and research with numerous faculty holding joint appointments in more than one Case Western Reserve school or department, as well as at neighboring institutions. These relationships launched many of the unique pairings of science, business and liberal arts into the centers and programs that enhance the undergraduate and graduate experience at the university. Our dual degree programs enrich the educational experience for those students who choose to balance the technical requirements of engineering or the sciences with a strong interest in the humanities.

With more than $375 million in research funding annually, the university attracts outstanding undergraduate and graduate students along with renowned faculty whose research has made significant contributions to the way we live and work. Case Western Reserve counts 15 Nobel laureates among our alumni and current and former faculty, including the first American scientist to ever receive the prize.

Our students' experiences in cultural institutions, clinics, social service agencies and industry are not viewed as “extra-curricular,” but create the learning experience that defines a Case Western Reserve education. The university's service programs in the Cleveland Municipal School District have impacted more than 145,000 students with more than 43 signature programs. The university has launched more than 580 community partnerships on the local, national and international levels. Annually the university sponsors Case for Community Day, an event where hundreds of Case Western Reserve employees and students lend their time and talent to targeted community development projects in the Greater Cleveland area.

Our alumni number more than 110,000 and constitute a “who's who” of every profession. Alumni represent one of the university's strongest resources, playing a vital role in campus life through their work as advisors, mentors, friends and advocates.

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