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Duke University
Center for Study of Aging
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Job Details

School of Medicine:

Established in 1930, Duke University School of Medicine is the youngest of the nation’s top medical schools. Ranked tenth among its peers, the School takes pride in being an inclusive community of outstanding learners, investigators, clinicians, and staff where traditional barriers are low, interdisciplinary collaboration is embraced, and great ideas accelerate translation of fundamental scientific discoveries to improve humanhealth locally and around the globe.

Comprised of 2,400 faculty physicians and researchers, the Duke University School of Medicine along with the Duke University School of Nursing and Duke University Health System create Duke Health. Duke Health is a world-class health care network. Founded in 1998 to provide efficient, responsive care, the health system offers a full network of health services and encompasses Duke University Hospital, Duke Regional Hospital, Duke Raleigh Hospital, Duke Primary Care, Private Diagnostic Clinic, Duke Home and Hospice, Duke Health and Wellness, and multiple affiliations.

Duke Aging Center

The Center for the Study of Aging and Human Development (Duke Aging Center) in Duke University’s School of Medicine houses the Aging Center Data Science & Statistics Core (DSS). The DSS Core is a small group with 4 PhD statisticians, a data manager, and 3 master’s level statisticians. The PhD statisticians will provide support for the position, and, the position can require supervision and support of junior statisticians.Offices are in Duke South Clinics building close to Duke’s main campus.

Occupational Summary

DSS team members support grants, Program Projects, Clinical Trials, Pilots, and junior and senior clinical faculty in aging/geriatrics. The studies are interdisciplinary, and range from the population to molecular level. This position is expected to be part of the research teams and be engaged in and contribute to statistical meetings and to meetings of the team with clinical researchers. Work flow will typically involve effort on several ongoing projects simultaneously at various stage of completion, both working in a team, leading junior statisticians, working alone on project tasks, 1:1 consultation with researchers, and may involve methodologic statistical work of interest to the greater statistical literature. The candidate will contribute leadership in these activities.

Work Performed:

The position will support several types of activities, and will require knowledge of both introductory and some high-level statistics. There is no expectation of expertise for working knowledge in all the fields below.

    Design - The candidate will lead or assist in the design of a range of study proposals – including pilot studies, to observational studies of Electronic Health Record, and phase IV clinical trials. For many projects, development of a Statistical Analysis Plans (SAP). The position contributes to the thought process of endpoint selection and study design, which can require Calculation of samples sizes, power calculations, and interim stopping guidelines – all with guidance. The position provides review and approval of data collection tools data correction criteria and procedures, identification of critical data fields, and endpoint collection documents. Understands study data and the intricacies of the process through which it is being collected.Documenting analysis and results, including write-up of methods and results for publications, including graphics.Collaborates effectively with statistical programmers and data managers that support clinical trial/projects. Identifies potential data problems from analytic queries and takes appropriate initiative to guide the process of resolution. Can identify problems in data management and offer solutions.Coding - Writes own SAS and/or R code, finds errors, corrects, and validates output and results. Performs complex programming efficiently, uses complicated SAS procedures and options. Working with data manager, can manipulate data sets to derive required analyses. Document code. For some applications, Mplus is employed.Participates in all statistical aspects of a trial/project with minimal guidance – including serving as lead statistician. Collaborates with project leader, principal investigator, other clinical investigators, and external government or industry representatives to affect significant decisions regarding the trial/project, and to jointly achieve objectives and timelines. The statistician may lead the design and analysis component of the project or serve as team member. Represents the functional group in project team meetings and contributes constructively to project discussions.Project management. Generates project randomization sequences provides input and review of telephone-based or internet-based randomization system specifications. Provides review and approval of data collection tools, data correction criteria and procedures, identification of critical data fields, and endpoint collection documents. Understands study data and the intricacies of the process through which it is being collected.Consultation with clinical investigators - Consistently handles multiple competing projects and deadlines. Presents information on topics relevant to statistics and statistical operations at internal statistics meetings. Gives oral presentations of key statistical methods, operational issues, study results, or project status.Performance of basic and advanced biostatistical techniques, including methods in the analysis of clinical trials, longitudinal and survival analysis, observational analysis, analysis in the presence of missing data, and psychometrics. Knowledge of Principal Components Analysis, genetic analysis, Machine Learning/Artificial Intelligence, of Structural Equation Models is a plus.

Required Qualifications Education/Training:

Position requires a minimum of a Doctoral degree in (bio) statistics or related field and 0-2 years of relevant experience, or a master's degree in (bio) statistics or related field and 4 years of relevant experience, or a bachelor's degree in (bio) statistics or related field and 6 years of relevant experience.



Experience as a lead statistician on clinical trials and/or clinical research projects that have consistently provided high quality end products on time, and prior supervision and/or guidance of lower level or less experienced employees is required. Thorough experience with SAS and solid command of the English language is required. Strong technical writing skills and multiple and varied prior trial/project experiences desirable.

The intent of this job description is to provide a representative and level of the types of duties and responsibilities that will be required of positions given this title and shall not be construed as a declaration of the total of the specific duties and responsibilities of any particular position. Employees may be directed to perform job­related tasks other than those specifically presented in this description.

Duke is an Affirmative Action/Equal Opportunity Employer committed to providing employment opportunity without regard to an individual's age, color, disability, gender, gender expression, gender identity, genetic information, national origin, race, religion, sex, sexual orientation, or veteran status.

Duke aspires to create a community built on collaboration, innovation, creativity, and belonging. Our collective success depends on the robust exchange of ideas—an exchange that is best when the rich diversity of our perspectives, backgrounds, and experiences flourishes. To achieve this exchange, it is essential that all members of the community feel secure and welcome, that the contributions of all individuals are respected, and that all voices are heard. All members of our community have a responsibility to uphold these values.

Essential Physical Job Functions: Certain jobs at Duke University and Duke University Health System may include essentialjob functions that require specific physical and/or mental abilities. Additional information and provision for requests for reasonable accommodation will be provided by each hiring department.


Read our Diversity Profile History

Duke University was created in 1924 by James Buchanan Duke as a memorial to his father, Washington Duke. The Dukes, a Durham family that built a worldwide financial empire in the manufacture of tobacco products and developed electricity production in the Carolinas, long had been interested in Trinity College. Trinity traced its roots to 1838 in nearby Randolph County when local Methodist and Quaker communities opened Union Institute. The school, then named Trinity College, moved to Durham in 1892, where Benjamin Newton Duke served as a primary benefactor and link with the Duke family until his death in 1929. In December 1924, the provisions of indenture by Benjamin’s brother, James B. Duke, created the family philanthropic foundation, The Duke Endowment, which provided for the expansion of Trinity College into Duke University.Duke Campus

As a result of the Duke gift, Trinity underwent both physical and academic expansion. The original Durham campus became known as East Campus when it was rebuilt in stately Georgian architecture. West Campus, Gothic in style and dominated by the soaring 210-foot tower of Duke Chapel, opened in 1930. East Campus served as home of the Woman's College of Duke University until 1972, when the men's and women's undergraduate colleges merged. Both men and women undergraduates now enroll in either the Trinity College of Arts & Sciences or the Pratt School of Engineering. In 1995, East Campus became the home for all first-year students.

Duke maintains a historic affiliation with the United Methodist Church.

Home of the Blue Devils, Duke University has about 13,000 undergraduate and graduate students and a world-class faculty helping to expand the frontiers of knowledge. The university has a strong commitment to applying knowledge in service to society, both near its North Carolina campus and around the world.

Mission Statement

Duke Science"James B. Duke's founding Indenture of Duke University directed the members of the University to 'provide real leadership in the educational world' by choosing individuals of 'outstanding character, ability, and vision' to serve as its officers, trustees and faculty; by carefully selecting students of 'character, determination and application;' and by pursuing those areas of teaching and scholarship that would 'most help to develop our resources, increase our wisdom, and promote human happiness.'

“To these ends, the mission of Duke University is to provide a superior liberal education to undergraduate students, attending not only to their intellectual growth but also to their development as adults committed to high ethical standards and full participation as leaders in their communities; to prepare future members of the learned professions for lives of skilled and ethical service by providing excellent graduate and professional education; to advance the frontiers of knowledge and contribute boldly to the international community of scholarship; to promote an intellectual environment built on a commitment to free and open inquiry; to help those who suffer, cure disease, and promote health, through sophisticated medical research and thoughtful patient care; to provide wide ranging educational opportunities, on and beyond our campuses, for traditional students, active professionals and life-long learners using the power of information technologies; and to promote a deep appreciation for the range of human difference and potential, a sense of the obligations and rewards of citizenship, and a commitment to learning, freedom and truth.Duke Meeting

 “By pursuing these objectives with vision and integrity, Duke University seeks to engage the mind, elevate the spirit, and stimulate the best effort of all who are associated with the University; to contribute in diverse ways to the local community, the state, the nation and the world; and to attain and maintain a place of real leadership in all that we do.”

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