Postdoctoral Research Scholar (Translational Research in Pain)

NC State University
Raleigh, NC
Closing date
Oct 22, 2021

Job Details

Posting Number:


Position Number:


Position Type:

Post Doc

Department ID:

195001 - Dept of Clinical Sciences


195001 - Dept of Clinical Sciences

Job City & State:

Raleigh, NC

Essential Job Duties:

The Department of Clinical Sciences is dedicated to excellence in educating and training veterinarians and comparative biomedical scientists, furthering health care and wellness through discovery and clinical research, providing outstanding and compassionate medical care to a diverse range of animal patients, effectively engaging the animal-owning public, government and industry partners, and providing leadership in integrating biomedical sciences to advance One Health.
North Carolina State University’s College of Veterinary Medicine (CVM) is a dynamic community whose members are dedicated to preparing veterinarians and veterinarian scientists while advancing animal and human health from the cellular level through entire ecosystems.

The college is committed to practicing inclusivity, making community a priority and promoting innovation. We embrace effective leadership and we champion personal and professional growth.

Duties & Responsibilities:
The Translational Research in Pain (TRiP) Program is a translational and basic pain research lab at North Carolina State University that studies both: (1) mechanisms of musculoskeletal pain, and (2) therapeutics for musculoskeletal pain.
A postdoctoral research scholar position is immediately available. This 4/5-yr project involves work with 3 species (mouse, rat and dog). The work is centered on understanding the utility of targeting VEGF receptors for the management of osteoarthritis and osteoarthritis pain. Our central hypothesis is that targeting both VEGF-1 and VEGF-2 simultaneously elicits dual function: (i) immediate symptom alleviation and (ii) inhibition of cartilage tissue degeneration. Thus, both disease progression and pain are halted. This hypothesis will be rigorously tested using: 1) Different types of target inhibitors – mAbs and small molecules; 2) Two different mouse and rat OA models, and two different dog OA models (including client-owned pet dogs with osteoarthritis). The project involves behavioral assays of pain, function and movement in all species; benchtop molecular biology assays (e.g., qPCR, Western blot, immunohistochemistry, Ca2+ imaging, in-situ hybridization); histology. This will be a two-year minimum position.
Our group has strong connections and collaborations with pain researchers at UNC Chapel Hill and Duke University.
The selected candidate will work under the direct guidance of Dr. Duncan Lascelles, a translational pain researcher, veterinarian and Specialist in Small Animal Surgery. The selected candidate will work with a technician dedicated to the project. Other team members include 2-3 graduate students; 2 Veterinarian Research Assistants; 2 Research Specialist Technicians; undergraduate students. Close on-site faculty collaborators include Drs. Santosh Mishra (neurobiologist and itch researcher with particular expertise in mouse modeling), Margaret Gruen (veterinarian, Specialist in Behavior, pain researcher) and Mike Nolan (Radiation Oncologist and cancer/pain researcher). We hope you will consider joining us!
The postdoctoral associate will be expected to carry out independent work, make presentations regarding his/her research, to publish their research results in peer-reviewed journals, to participate in grant proposal preparation, and to interact with other faculty, postdoctoral associates, and graduate students at the University level and across collaborating institutions of the project. All aspects of work will be closely mentored with the goal of transitioning the incumbent to be an independently funded researcher in the area of pain.

Other Work/Responsibilities:

Some Laboratory Manager duties (organizing lab meetings; ordering; equipment repair and maintenance)

Work Schedule:

Variable but typically M-F 8 hours/day

Department Required Skills:

Strong interpersonal skills; strong organizational skills; strong communication skills; strong work ethic.
Experience with basic benchtop molecular biology assays (e.g., qPCR, Western blot, immunohistochemistry)
Experience with behavioral assays in mice and rats

Preferred Years Experience, Skills, Training, Education:

Experience working with dogs preferred
Previous grant writing experience preferred
Experience in behavioral pain research.
Experience in molecular pain research.

Required License or Certification:


Valid NC Driver's License required?:


Commercial Driver's License Required?:


Anticipated Hiring Range:

$55,000 - $60,000

Job Open Date:


Quick Link:


NC State University is an equal opportunity and affirmative action employer. All qualified applicants will receive consideration for employment without regard to race, color, national origin, religion, sex, gender identity, age, sexual orientation, genetic information, status as an individual with a disability, or status as a protected veteran.

If you have general questions about the application process, you may contact Human Resources at (919) 515-2135 or [email protected] Individuals with disabilities requiring disability-related accommodations in the application and interview process, please call 919-515-3148.

Final candidates are subject to criminal & sex offender background checks. Some vacancies also require credit or motor vehicle checks. If highest degree is from an institution outside of the U.S., final candidates are required to have their degree equivalency verified at or equivalent service. Degree(s) must be obtained prior to start date in order to meet qualifications and receive credit.

NC State University participates in E-Verify. Federal law requires all employers to verify the identity and employment eligibility of all persons hired to work in the United States.


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