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Postdoctoral Research Scholar (Translational Research in Pain)

Employer
NC State University
Location
Raleigh, NC

View more

Position Type
Postdoc
Employment Type
Full Time
Institution Type
Four-Year Institution

Job Details

Posting Number:

PG190453PD

Position Number:

00108580

Position Type:

Post Doc

Department ID:

195001 - Dept of Clinical Sciences

Department:

195001 - Dept of Clinical Sciences

Job City & State:

Raleigh, NC

Essential Job Duties:

The Department of Clinical Sciences is dedicated to excellence in educating and training veterinarians and comparative biomedical scientists, furthering health care and wellness through discovery and clinical research, providing outstanding and compassionate medical care to a diverse range of animal patients, effectively engaging the animal-owning public, government and industry partners, and providing leadership in integrating biomedical sciences to advance One Health.
North Carolina State University’s College of Veterinary Medicine (CVM) is a dynamic community whose members are dedicated to preparing veterinarians and veterinarian scientists while advancing animal and human health from the cellular level through entire ecosystems.

The college is committed to practicing inclusivity, making community a priority and promoting innovation. We embrace effective leadership and we champion personal and professional growth.

Duties & Responsibilities:
The Translational Research in Pain (TRiP) Program is a translational and basic pain research lab at North Carolina State University that studies both: (1) mechanisms of musculoskeletal pain, and (2) therapeutics for musculoskeletal pain.
A postdoctoral research scholar position is immediately available. This 4/5-yr project involves work with 3 species (mouse, rat and dog). The work is centered on understanding the utility of targeting VEGF receptors for the management of osteoarthritis and osteoarthritis pain. Our central hypothesis is that targeting both VEGF-1 and VEGF-2 simultaneously elicits dual function: (i) immediate symptom alleviation and (ii) inhibition of cartilage tissue degeneration. Thus, both disease progression and pain are halted. This hypothesis will be rigorously tested using: 1) Different types of target inhibitors – mAbs and small molecules; 2) Two different mouse and rat OA models, and two different dog OA models (including client-owned pet dogs with osteoarthritis). The project involves behavioral assays of pain, function and movement in all species; benchtop molecular biology assays (e.g., qPCR, Western blot, immunohistochemistry, Ca2+ imaging, in-situ hybridization); histology. This will be a two-year minimum position.
Our group has strong connections and collaborations with pain researchers at UNC Chapel Hill and Duke University.
The selected candidate will work under the direct guidance of Dr. Duncan Lascelles, a translational pain researcher, veterinarian and Specialist in Small Animal Surgery. The selected candidate will work with a technician dedicated to the project. Other team members include 2-3 graduate students; 2 Veterinarian Research Assistants; 2 Research Specialist Technicians; undergraduate students. Close on-site faculty collaborators include Drs. Santosh Mishra (neurobiologist and itch researcher with particular expertise in mouse modeling), Margaret Gruen (veterinarian, Specialist in Behavior, pain researcher) and Mike Nolan (Radiation Oncologist and cancer/pain researcher). We hope you will consider joining us!
The postdoctoral associate will be expected to carry out independent work, make presentations regarding his/her research, to publish their research results in peer-reviewed journals, to participate in grant proposal preparation, and to interact with other faculty, postdoctoral associates, and graduate students at the University level and across collaborating institutions of the project. All aspects of work will be closely mentored with the goal of transitioning the incumbent to be an independently funded researcher in the area of pain.

Other Work/Responsibilities:

Some Laboratory Manager duties (organizing lab meetings; ordering; equipment repair and maintenance)

Work Schedule:

Variable but typically M-F 8 hours/day

Department Required Skills:

Strong interpersonal skills; strong organizational skills; strong communication skills; strong work ethic.
Experience with basic benchtop molecular biology assays (e.g., qPCR, Western blot, immunohistochemistry)
Experience with behavioral assays in mice and rats

Preferred Years Experience, Skills, Training, Education:

Experience working with dogs preferred
Previous grant writing experience preferred
Experience in behavioral pain research.
Experience in molecular pain research.

Required License or Certification:

N/A

Valid NC Driver's License required?:

No

Commercial Driver's License Required?:

No

Anticipated Hiring Range:

$55,000 - $60,000

Job Open Date:

06/10/2021

Quick Link:

https://jobs.ncsu.edu/postings/145302

AA/EEO:

NC State University is an equal opportunity and affirmative action employer. All qualified applicants will receive consideration for employment without regard to race, color, national origin, religion, sex, gender identity, age, sexual orientation, genetic information, status as an individual with a disability, or status as a protected veteran.

If you have general questions about the application process, you may contact Human Resources at (919) 515-2135 or workatncstate@ncsu.edu. Individuals with disabilities requiring disability-related accommodations in the application and interview process, please call 919-515-3148.

Final candidates are subject to criminal & sex offender background checks. Some vacancies also require credit or motor vehicle checks. If highest degree is from an institution outside of the U.S., final candidates are required to have their degree equivalency verified at www.wes.org or equivalent service. Degree(s) must be obtained prior to start date in order to meet qualifications and receive credit.

NC State University participates in E-Verify. Federal law requires all employers to verify the identity and employment eligibility of all persons hired to work in the United States.

Organization

NC State: Think and Do

NC State was founded with a purpose: to create economic, societal and intellectual prosperity for the people of North Carolina and the country. We began as a land-grant institution teaching the agricultural and mechanical arts. Today, we're a pre-eminent research enterprise with 12 colleges excelling in all major academic fields.

NC State studentsOur 34,000 high-performing students take what they learn in the classroom and apply it in the real world by conducting research, working in internships and co-ops, and performing acts of world-changing service. That experiential education ensures that they leave here ready to lead the workforce. NC State's 13:1 student-faculty ratio is one of the reasons why we're the best college for your money in North Carolina (Money) and the No. 5 best value among public universities nationally (U.S. News & World Report).

Overcoming Challenges, Improving Lives

NC State is one of only two universities in the nation leading two National Science Foundation Engineering Research Centers — one developing wearable, self-powered health monitors, and the other researching smart-grid technology. We’re also leading interdisciplinary efforts to curb nuclear proliferation, help farmers confront climate change and build a new American manufacturing sector.

Our research doesn't just get published in a journal or sit on a shelf; it makes an impact. NC State is No. 6 nationwide in commercialization agreements based on university research, and we're No. 2 among universities without a medical school. Our Cooperative Extension Service provides research-based information to citizens in all 100 North Carolina counties. In addition, our industrial extension unit — Industry Expansion Solutions — has created an economic benefit for the state's manufacturers averaging $149 million per year since 2005.

Bright Minds Creating a Bold Future

NC State’s 9,000 faculty and staff are world leaders in their fields, bridging the divides between academic disciplines and training high-caliber students to meet tomorrow’s challenges. NC State students won two Goldwater scholarships, five Fulbright scholarships, one Churchill scholarship and a record-breaking 25 National Science Foundation graduate research fellowships in the 2016-2017 academic year. In addition, 25 faculty are members of the National Academies.

NC State bldg in darkOur Centennial Campus, an award-winning public-private research campus, is home to more than 70 partner organizations working alongside more than 70 NC State research and academic units. Centennial is also the location of the innovative Hunt Library, which Time magazine has dubbed “the library of the future.”

In Raleigh and Around the World

It all happens in one of the best cities in America. A top spot for job-seekers and tech professionals, Raleigh is nationally recognized as a leading urban center:

NC State building oldWith Durham and Chapel Hill, Raleigh anchors the Research Triangle, a national hotspot for high-tech enterprise. The top companies in the region — including IBM, Cisco Systems, SAS Institute, Biogen Idec and GlaxoSmithKline — are among the country’s best employers. They also lead the way in hiring new NC State graduates.

More than 130 years after its creation, NC State continues to make its founding purpose a reality. Every day, our career-ready graduates and world-leading faculty make the fruits of learning and discovery available to people across the state, throughout the nation and around the world.

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