Research Assistant 2
- Employer
- Case Western Reserve University
- Location
- Case Main Campus
View more
- Administrative Jobs
- Academic Affairs, Research Staff & Technicians
- Employment Type
- Full Time
- Institution Type
- Four-Year Institution
Job Details
Location: Case Main Campus
Regular/Temporary: Regular
Full/Part Time: Full-Time
Job ID: 8925
Job Description POSITION OBJECTIVEWorking under general supervision, the Research Assistant 2 will plan and carry out experimental work to support researchers in projects aimed at understanding the molecular mechanisms of HIV latency including the effect of estrogen on HIV infection and latency and latency in primary TH17 cells. This position will require work with human tissue and blood samples. ESSENTIAL FUNCTIONS
- Plan and carry out research projects in accordance with general plans. Prepare cells for use in the HIV latency models, including iPSC cells, maintain and grow lentiviral vectors and viral stocks and assist in experiments involving these materials. Research assignments include cell culture work, including coordination and pick up of blood draws; isolation of primary T-cells, viral transfections and infections; DNA isolation and manipulation (i.e., cloning, gel electrophoresis) and flow cytometry. (40%)Conduct a series of experiments including new protocols and techniques for research projects to improve the development of HIV latency models in primary T-cells and microglial cells. May assist in developing improved techniques, protocols and procedures. (12%)Collect and analyze data, prepare graphs, charts and slides from experimental data for purposes of reporting. Data analysis includes the systematic evaluation of different protocols to optimize cell viability, yield and infectivity rates. Maintain meticulous records of experiments. (14%)Train new staff, direct the work of students. Responsible for technical training of new staff, graduate students and undergraduates regarding laboratory policies as well as basic molecular virology techniques. (14%)Participate in weekly one-on-one meetings with principal investigator and weekly group laboratory meetings. Present and analyze data during weekly lab group meetings. (11%)
- Ensure that the laboratory complies with environmental health and safety requirements. (3%)Oversee inventory, handle purchase orders, perform general lab maintenance and tasks. (2%)Attend departmental seminars and research retreats. (2%)Perform other duties as assigned. (2%)
- Must possess knowledge and technical skills in: Sterile technique; reagent and media preparation; mammalian cell culture. Experience with virology and/or viral vectors preferred.Excellent communication and organizational skills, with the ability to multi-task.Ability to operate laboratory equipment including advanced instruments such as flow cytometers, liquid handling robots, PCR machines.Strong organization skills and good habit of maintaining a clean lab working environment; demonstrate attention to detail and accuracy, time management skills and proven ability to successfully follow-through on assigned projects.Must be able to and willing to learn new techniques, procedures, processes and computer software/hardware to perform experiments. Ability to work effectively independently and collaboratively within a team. Must be highly motivated, responsible, dependable and a self-starter.Professional and effective verbal and written communication skills and good interpersonal skills with the ability to work and communicate with various individuals within and external to the laboratory, Department and University.Ability to work with sensitive information and maintain confidentiality.Ability to rely on instructions and pre-established guidelines to perform the functions of the job. Ability to operate laboratory equipment.Ability to meet consistent attendance.Ability to interact with colleagues, supervisors and customers face to face.Proficiency in routine computer use such as ability to use Microsoft Office and database programs.
In employment, as in education, Case Western Reserve University is committed to Equal Opportunity and Diversity. Women, veterans, members of underrepresented minority groups, and individuals with disabilities are encouraged to apply.
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Reasonable AccommodationsCase Western Reserve University provides reasonable accommodations to applicants with disabilities. Applicants requiring a reasonable accommodation for any part of the application and hiring process should contact the Office of Equity at 216-368-3066 to request a reasonable accommodation. Determinations as to granting reasonable accommodations for any applicant will be made on a case-by-case basis.
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Organization
Working at Case Western Reserve University
Case Western Reserve University is among the nation's leading research institutions. Founded in 1826 and shaped by the unique merger of the Case Institute of Technology and Western Reserve University, Case Western Reserve is distinguished by its strengths in education, research, service and experiential learning. Located in Cleveland's University Circle, we offer nationally recognized programs in the arts and sciences, dental medicine, engineering, law, management, medicine, nursing and social sciences.
Student enrollment exceeds 9,800 students, forty percent of whom are undergraduates. Facultyand students hail from more than 90 countries, with academic interests that reach every region of the world. Case Western Reserve, with the support of individuals, corporations and foundations, aids nearly 100 designated research centers.
As a service-oriented institution dedicated to civic leadership, Case Western Reserve seeks individually and collectively to prepare our students to improve the human condition and to direct the benefits of discovery toward a better society. This effort is not limited to the university's classrooms, laboratories, libraries, residence halls and athletic fields, but includes partnerships with many other institutions. We build these partnerships believing that our ability to improve the human condition should begin in our own community.
Case Western Reserve University remains Ohio's top-ranked school among the nation's premier national universities, as ranked by U.S. News & World Report and is the only Ohio institution ranked in the top 50 nationally. We promote a culture of inquiry marked by rigor, creativity, curiosity, innovation, respect, sensitivity and open communication of ideas.
The university supports interdisciplinary partnerships in education and research with numerous faculty holding joint appointments in more than one Case Western Reserve school or department, as well as at neighboring institutions. These relationships launched many of the unique pairings of science, business and liberal arts into the centers and programs that enhance the undergraduate and graduate experience at the university. Our dual degree programs enrich the educational experience for those students who choose to balance the technical requirements of engineering or the sciences with a strong interest in the humanities.
With more than $375 million in research funding annually, the university attracts outstanding undergraduate and graduate students along with renowned faculty whose research has made significant contributions to the way we live and work. Case Western Reserve counts 15 Nobel laureates among our alumni and current and former faculty, including the first American scientist to ever receive the prize.
Our students' experiences in cultural institutions, clinics, social service agencies and industry are not viewed as “extra-curricular,” but create the learning experience that defines a Case Western Reserve education. The university's service programs in the Cleveland Municipal School District have impacted more than 145,000 students with more than 43 signature programs. The university has launched more than 580 community partnerships on the local, national and international levels. Annually the university sponsors Case for Community Day, an event where hundreds of Case Western Reserve employees and students lend their time and talent to targeted community development projects in the Greater Cleveland area.
Our alumni number more than 110,000 and constitute a “who's who” of every profession. Alumni represent one of the university's strongest resources, playing a vital role in campus life through their work as advisors, mentors, friends and advocates.
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