Professional Research Assistant

Job description

University of Colorado Denver School of Medicine

Department of Immunology and Microbiology and Department of Anesthesiology

Laboratories of Dr. Linda van Dyk and Dr. Eric Clambey

Professional Research Assistant     Position #   00784800              Posting # 21612

The University of Colorado Denver l Anschutz Medical Campus seeks individuals with demonstrated commitment to creating an inclusive learning and working environment.  We value the ability to engage effectively with students, faculty and staff of diverse backgrounds.


This PRA position is a full-time, 1.0 FTE research position to work on virology, molecular biology, immunology, and pathogenesis of infection and cancer.  This full-time position involves research in virology, immunology, molecular biology and pathogenesis, including work to analyze recombinant viruses, cell culture systems and mouse models.  Responsibilities include work with cell and molecular biology, virus growth and quantitation, recombinant DNA work, multiparametric flow cytometry, analysis of viruses and host responses in mouse models for determination of virus infection and of disease, including tumorigenesis.  The position requires carefully following instructions for a wide variety of laboratory procedures that will be demonstrated or described, keeping excellent, well organized and up-to-date records of experiments, organizing samples for later analyses, ordering supplies in a timely and efficient manner, maintaining equipment in proper working order or promptly arranging for repair of instruments. Maintaining a neat and orderly laboratory is required. Laboratory administrative duties include placing orders for lab supplies, mailing packages to colleagues, helping with preparation of grant applications and manuscripts, preparation of slides and figures, and maintaining financial records. Occasionally, the incumbent will prepare and present results for presentation and group discussions and will instruct others in laboratory techniques when requested by the lab head. The incumbent is expected to work effectively with students, post-doctoral fellows and other lab members.


The employee will be supervised by the heads of the laboratory, Dr. Linda van Dyk and Dr. Eric Clambey, and will work with members of laboratory staff as assigned.


After initial training in animal work, cell culture and other techniques, this PRA may also help to train and supervise the undergraduate student workers and rotating graduate students or medical students.


  • Direct involvement in murine studies, including virus pathogenesis, lung inflammation (including tumorigenesis), followed by tissue isolation, processing and analysis. These experiments often involve time courses from days to weeks.
  • Multi-parameter flow cytometric analysis.
  • Viral propagation and quantitation using cell culture and plaque assays.
  • Harvest and asceptic purification of primary leukocyte populations followed by in vitro culture and manipulation.
  • Tissue culture work including feeding and splitting of cultured cell lines, and work with transient and stable transfection methodologies, including plasmid-based luciferase assays and siRNA silenced cell lines.
  • Molecular biology work including DNA and RNA purification, polymerase chain reaction (PCR) and real-time reverse transcriptional polymerase chain reaction (RT-PCR), protein analysis, including antibody-based flow-cytometric analysis and enzyme-linked immunosorbent assay (ELISA); histological techniques such as tissue sections, staining and immunohistochemistry.
  • All research tasks require careful data gathering and documentation.
  • Assistance with data interpretation and analysis.
  • Lab ordering, record keeping and maintenance.

The research will involve, growth, purification and analysis of infectious viruses, recombinant DNA studies, infection of animals, and use of chemicals.  The University regulations for work with animals, biohazards, recombinant DNA must be followed.  Occasionally experimental protocols may require working in the evening or working on weekends and holidays.


Grant funded


The salary range (or hiring range) has been established at $38,000 to $45,000.

The salary of the finalist(s) selected for this role will be set based on a variety of factors, including but not limited to, internal equity, experience, education, specialty and training.

The above salary range (or hiring range) represents the University’s good faith and reasonable estimate of the range of possible compensation at the time of posting.

The University of Colorado offers a full benefits package. Information on University benefits programs, including eligibility, is located at Employee Services.


University of Colorado Denver | Anschutz Medical Campus is dedicated to ensuring a safe and secure environment for our faculty, staff, students and visitors. To assist in achieving that goal, we conduct background checks for all new employees prior to their employment.


The Immigration Reform and Control Act requires that verification of employment eligibility be documented for all new employees by the end of the third day of work. Alternative formats of this ad are available upon request for persons with disabilities.


Your total compensation goes beyond the number on your paycheck. The University of Colorado provides generous leave, health plans and retirement contributions that add to your bottom line.



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Diversity and Equity:


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Office of Equity:


The University of Colorado Denver | Anschutz Medical Campus is committed to recruiting and supporting a diverse student body, faculty and administrative staff. The university strives to promote a culture of inclusiveness, respect, communication and understanding. We encourage applications from women, ethnic minorities, persons with disabilities and all veterans. The University of Colorado is committed to diversity and equality in education and employment.



      B.S. or B.A. degree in microbiology, molecular biology, biochemistry, genetics, cell biology, immunology or closely related field is required. 
    Applicants must meet minimum qualifications at the time of hire.


      Previous laboratory experience in molecular biology, cell culture, virology, flow cytometry, handling of laboratory animals and computer/administrative skills.  Experience in immunology and RNA biology is desirable, as is knowledge of R or Python.
    Competencies/Knowledge, SKills and Abilties

      Good computer skills are required.  Applicants should demonstrate they are well organized, reliable, independent, and have excellent verbal and written communication skills. Applicants should be able to quickly adapt to new challenges, show willingness to learn and have good interaction skills. 

    Job Category: Faculty
    Primary Location: Aurora
    Schedule: Full-time
    Posting Date: Jun 7, 2021
    Unposting Date: Ongoing




    Diversity Profile: University



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    Job No:
    Posted: 6/9/2021
    Application Due: 9/7/2021
    Work Type: Full Time