Director D, Human Genome Editing Lab Employee (Center for Cellular Immunotherapy)

Job description

Job location: Smilow Center for Translational


Employment Type: Full-time
Posted data: 2021-06-03
Req: JR00033775
University Overview

The University of Pennsylvania, the largest private employer in Philadelphia, is a world-renowned leader in education, research, and innovation. This historic, Ivy League school consistently ranks among the top 10 universities in the annual U.S. News & World Report survey. Penn has 12 highly-regarded schools that provide opportunities for undergraduate, graduate and continuing education, all influenced by Penn’s distinctive interdisciplinary approach to scholarship and learning.

Penn offers a unique working environment within the city of Philadelphia. The University is situated on a beautiful urban campus, with easy access to a range of educational, cultural, and recreational activities. With its historical significance and landmarks, lively cultural offerings, and wide variety of atmospheres, Philadelphia is the perfect place to call home for work and play.

The University offers a competitive benefits package that includes excellent healthcare and tuition benefits for employees and their families, generous retirement benefits, a wide variety of professional development opportunities, supportive work and family benefits, a wealth of health and wellness programs and resources, and much more.

Posted Job Title

Director D, Human Genome Editing Lab Employee (Center for Cellular Immunotherapy)

Job Profile Title

Director D

Job Description Summary

This position will serve as Director of the Human Genome Editing (HGE) Lab within the Center for Cellular Immunotherapies (CCI), and will report directly to the Director of CCI. The Director of HGE will be responsible for establishing and leading a team capable of translating proof-of-concept preclinical benchwork into cellular therapies for patients. The HGE Director will provide expert scientific input for stem cell manufacturing, gene editing, analytical testing, and correlative science projects. The HGE Director will work closely with the Directors of the Product Development Lab (PDL), T-Cell Engineering Laboratory (TCEL), the Translational and Correlatives Studies Laboratory (TCSL), and the Clinical Cell and Vaccine Production Facility (CVPF) for seamless transition of projects and efficient resource utilization to support the mission of CCI.
The HGE Director will ensure the timely planning and execution of projects in HGE, including the preparation, review and approval of reports, presentations, scientific papers, and IND-enabling data packages for regulatory filing. He/she will present data at local, national and international meetings. The Director of HGE will monitor progress and timelines related to projects and provide updates to the Director of CCI. He or she will manage internal and external collaborations, including the Penn Center for Innovation (PCI) to ensure that required legal documents are in place, and keep track of legal documents associated with HGE projects. In addition, the HGE Director will ensure continuation of collaborative projects and engage in direct communication with Principal Investigators as necessary, as well as update and discuss collaborative projects. The HGE Director will form new academic and industry collaborations as they contribute to the mission of HGE at large, and will be responsible for the strategic development and prioritization of projects. The HGE Director will also submit grant applications for both internal and external funding to support the lab’s research.

Job Description

This position will serve as Director of the Human Genome Editing (HGE) Lab within the Center for Cellular Immunotherapies (CCI), and will report directly to the Director of CCI. The Director of HGE will be responsible for establishing and leading a team capable of translating proof-of-concept preclinical benchwork into cellular therapies for patients. The HGE Director will provide expert scientific input for stem cell manufacturing, gene editing, analytical testing, and correlative science projects. The HGE Director will work closely with the Directors of the Product Development Lab (PDL), T-Cell Engineering Laboratory (TCEL), the Translational and Correlatives Studies Laboratory (TCSL), and the Clinical Cell and Vaccine Production Facility (CVPF) for seamless transition of projects and efficient resource utilization to support the mission of CCI.
The HGE Director will ensure the timely planning and execution of projects in HGE, including the preparation, review and approval of reports, presentations, scientific papers, and IND-enabling data packages for regulatory filing. He/she will present data at local, national and international meetings. The Director of HGE will monitor progress and timelines related to projects and provide updates to the Director of CCI. He or she will manage internal and external collaborations, including the Penn Center for Innovation (PCI) to ensure that required legal documents are in place, and keep track of legal documents associated with HGE projects. In addition, the HGE Director will ensure continuation of collaborative projects and engage in direct communication with Principal Investigators as necessary, as well as update and discuss collaborative projects. The HGE Director will form new academic and industry collaborations as they contribute to the mission of HGE at large, and will be responsible for the strategic development and prioritization of projects. The HGE Director will also submit grant applications for both internal and external funding to support the lab’s research.

Requirements:
• Ph.D. in immunology or related discipline preferred; Master's Degree or equivalent combination of education and experience required
• Minimum of 5-7 years of academic and life sciences industrial experience with a demonstrated track record in stem cell and gene editing research, development, and application required; 10 years preferred.
• Extensive experience with cell culture methods, viral and non-viral transduction techniques, and various gene editing modalities and techniques, flow cytometry, immunological assays and cell biology analytical techniques
• Comfortable in a fast-paced, collaborative environment, working with minimal direction and able to adjust workload based upon changing priorities
• Demonstrated leadership and communication skills and the ability to collaborate with and effectively influence others
• Demonstrated experience in mentoring and training
• Highly functioning, detail-oriented, and analytical candidate who can think strategically and holistically about technology and product development, and collaborative efforts across laboratories with CCI
• Strong multitasking abilities and an extremely high-level of reliability and dependability
• Strong interpersonal skills
• Self-starter with a strong desire to innovate, contribute and work collaborative to achieve goals

This position is contingent upon funding.

Job Location - City, State

Philadelphia, Pennsylvania

Department / School

Perelman School of Medicine

Pay Range

$88,861.00 - $168,837.00

Affirmative Action Statement
Penn adheres to a policy that prohibits discrimination on the basis of race, color, sex, sexual orientation, gender identity, religion, creed, national or ethnic origin, citizenship status, age, disability, veteran status, or any other legally protected class.

Special Requirements
Background check required after a conditional job offer is made. Consideration of the background check will be tailored to the requirements of the job.

University Benefits

  • Health, Life, and Flexible Spending Accounts: Penn offers comprehensive medical, prescription, behavioral health, dental, vision, and life insurance benefits to protect you and your family’s health and welfare. You can also use flexible spending accounts to pay for eligible health care and dependent care expenses with pre-tax dollars.

  • Tuition: Take advantage of Penn's exceptional tuition benefits. You, your spouse, and your dependent children can get tuition assistance here at Penn. Your dependent children are also eligible for tuition assistance at other institutions.

  • Retirement: Penn offers generous retirement plans to help you save for your future. Penn’s Basic, Matching, and Supplemental retirement plans allow you to save for retirement on a pre-tax or Roth basis. Choose from a wide variety of investment options through TIAA and Vanguard.

  • Time Away from Work: Penn provides you with a substantial amount of time away from work during the course of the year. This allows you to relax, take vacations, attend to personal affairs, recover from illness or injury, spend time with family—whatever your personal needs may be.

  • Long-Term Care Insurance: In partnership with Genworth Financial, Penn offers faculty and staff (and your eligible family members) long-term care insurance to help you cover some of the costs of long-term care services received at home, in the community or in a nursing facility. If you apply when you’re newly hired, you won’t have to provide proof of good health or be subject to underwriting requirements. Eligible family members must always provide proof of good health and are subject to underwriting.

  • Wellness and Work-life Resources: Penn is committed to supporting our faculty and staff as they balance the competing demands of work and personal life. That’s why we offer a wide variety of programs and resources to help you care for your health, your family, and your work-life balance.

  • Professional and Personal Development: Penn provides an array of resources to help you advance yourself personally and professionally.

  • University Resources: As a member of the Penn community, you have access to a wide range of University resources as well as cultural and recreational activities. Take advantage of the University’s libraries and athletic facilities, or visit our arboretum and art galleries. There’s always something going on at Penn, whether it’s a new exhibit at the Penn Museum, the latest music or theater presentation at the Annenberg Center, or the Penn Relays at Franklin Field to name just a few examples. As a member of the Penn community, you’re right in the middle of the excitement—and you and your family can enjoy many of these activities for free.

  • Discounts and Special Services: From arts and entertainment to transportation and mortgages, you'll find great deals for University faculty and staff. Not only do Penn arts and cultural centers and museums offer free and discounted admission and memberships to faculty and staff. You can also enjoy substantial savings on other goods and services such as new cars from Ford and General Motors, cellular phone service plans, movie tickets, and admission to theme parks.

  • Flexible Work Hours: Flexible work options offer creative approaches for completing work while promoting balance between work and personal commitments. These approaches involve use of non-traditional work hours, locations, and/or job structures.

  • Penn Home Ownership Services: Penn offers a forgivable loan for eligible employees interested in buying a home or currently residing in West Philadelphia, which can be used for closing costs or home improvements.

  • Adoption Assistance: Penn will reimburse eligible employees on qualified expenses in connection with the legal adoption of an eligible child, such as travel or court fees, for up to two adoptions in your household.

To learn more, please visit: https://www.hr.upenn.edu/PennHR/benefits-pay

 

 

 

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Job No:
Posted: 6/4/2021
Application Due: 9/2/2021
Work Type: Full Time
Salary: