SRA II - Blood Disorders (9612C) 18959

Location
San Francisco
Posted
Jun 01, 2021
Employment Type
Full Time
Institution Type
Four-Year Institution


SRA II - Blood Disorders (9612C) 18959 About Berkeley

At the University of California, Berkeley, we are committed to creating a community that fosters equity of experience and opportunity, and ensures that students, faculty, and staff of all backgrounds feel safe, welcome and included. Our culture of openness, freedom and belonging make it a special place for students, faculty and staff.

The University of California, Berkeley, is one of the world's leading institutions of higher education, distinguished by its combination of internationally recognized academic and research excellence; the transformative opportunity it provides to a large and diverse student body; its public mission and commitment to equity and social justice; and its roots in the California experience, animated by such values as innovation, questioning the status quo, and respect for the environment and nature. Since its founding in 1868, Berkeley has fueled a perpetual renaissance, generating unparalleled intellectual, economic and social value in California, the United States and the world.

We are looking for equity-minded applicants who represent the full diversity of California and who demonstrate a sensitivity to and understanding of the diverse academic, socioeconomic, cultural, disability, gender identity, sexual orientation, and ethnic backgrounds present in our community. When you join the team at Berkeley, you can expect to be part of an inclusive, innovative and equity-focused community that approaches higher education as a matter of social justice that requires broad collaboration among faculty, staff, students and community partners. In deciding whether to apply for a position at Berkeley, you are strongly encouraged to consider whether your values align with our Guiding Values and Principles, our Principles of Community, and our Strategic Plan.

Application Review Date

The First Review Date for this job is: 6/7/2021

Departmental Overview

The Innovative Genomics Institute (IGI) is a multidisciplinary research institution focused on genome engineering and potential applications in agriculture, microbiology and biomedicine. It is a joint venture between UC Berkeley and UC San Francisco, with the administrative operations located on the Berkeley campus. This position is located at the UC Berkeley campus.

The IGI is presently seeking a talented and motivated Staff Research Associate (SRA) to conduct research towards clinical translation of genetic therapies for inherited blood disorders such as sickle cell disease, primary immunodeficiency and cancer. This work will be performed as part of a multidisciplinary team of genome engineers, stem cell biologists and immunologists at the Center for Translational Genomics (CTG) at UC Berkeley. Specific goals will be cell culture of primary and induced pluripotent stem cells, evaluation of new genome editing tools for cell therapy, the improvement of existing therapeutic approaches, and the assessment of ex vivo genome editing outcomes in human hematopoietic stem/progenitor cells (HSPCs) and/or T cells.

This position is ideal for candidates intending to pursue graduate or medical school education. The environment is exciting and fast-paced, and offers the opportunity to work at the cutting edge of genome editing and HSPC- and/or T cell-based therapies.


Responsibilities

The incumbent will work directly with the CTG Project Scientist and other SRA staff on setting up, conducting, and analyzing results from experiments on a daily basis. They will report to the CTG Director. This position will be central in developing a robust pipeline for gene therapy work in the CTG.
  • Under general supervision, perform a variety of repetitive but highly specialized laboratory experimental procedures in field of genome editing such as blood disorders like sickle cell disease, primary immunodeficiency, or cancer
  • Perform experiments involving lentivirus production and transduction
  • Execute and troubleshoot ex vivo delivery of genome editing reagents
  • Perform evaluation of genome editing experiments by next-gen sequencing, flow cytometry, and other assays
  • Modify, adapt or improve standard procedures to meet the needs of various projects
  • Acquire and apply skills in conducting research towards clinical translation of genetic therapies for inherited blood disorders

Required Qualifications
  • Strong organizational skills and attention to detail
  • Excellent oral and written communication skills

Preferred Qualifications
  • Experience working in a wet lab
  • Previous experience with
    • Gene editing
    • Preclinical mouse models
    • Stem cells
    • Tissue culture / sterile techniques
    • Flow cytometry
  • Knowledge of the development of genetic and/or cell-based therapies
  • Ability to keep proper industry-standard records
  • Ability to collaborate with researchers and work efficiently in a diverse group
  • Knowledge of the development and improvement of genome editing tools
  • B.A. or B.S. in Molecular Genetics, Cell Biology, Biochemistry, Bioengineering, or related discipline

Salary & Benefits

Salary commensurate with experience. For information on the comprehensive benefits package offered by the University visit:

https://ucnet.universityofcalifornia.edu/compensation-and-benefits/index.html

How to Apply

Please submit your cover letter and resume as a single attachment when applying.

Equal Employment Opportunity

The University of California is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, or protected veteran status. For more information about your rights as an applicant see:

https://www.eeoc.gov/sites/default/files/migrated_files/employers/poster_screen_reader_optimized.pdf
For the complete University of California nondiscrimination and affirmative action policy see:
http://policy.ucop.edu/doc/4000376/NondiscrimAffirmAct



To apply, visit https://careerspub.universityofcalifornia.edu/psp/ucb/EMPLOYEE/HRMS/c/HRS_HRAM.HRS_APP_SCHJOB.GBL?Page=HRS_APP_JBPST&Action=U&FOCUS=Applicant&SiteId=21&JobOpeningId=18959&PostingSeq=1





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