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Research Assistant 1

Case Western Reserve University
Case Main Campus
Closing date
Jun 28, 2021

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Academic Affairs, Research Staff & Technicians
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Job Details

Job Title: Research Assistant 1
Location: Case Main Campus
Regular/Temporary: Regular
Full/Part Time: Full-Time
Job ID: 8879

Working under general supervision, the Research Assistant 1 will perform research experiments in medical and related technical areas. The research assistant will maintain specialized knockout and transgenic mice uniquely developed in the lab for studies in basic immunology. The research assistant will also perform basic immunology experiments to look at inflammatory molecules in order to discover underlying pathogenic mechanisms that cause chronic intestinal inflammation, such as that observed in patients with inflammatory bowel disease. This position will work with animals.


    Maintain, organize, and perform minor husbandry of animal colonies. This includes but is not limited to providing care for animals, inspecting animals regularly, maintaining ID/records of all animals, and keeping datasheets up-to-date and circulated appropriately. Requires extensive and delicate handling of animals. (25%)Conduct procedures and experiments according to specific experimental protocols. These include measurements of inflammatory molecules at the gene levels (by quantitative polymerase chain reaction experiments) and at the protein levels (by Western blot experiments, enzyme-linked immunosorbent assay; ELISA, or immunohistochemistry techniques). (20%)Aid in managing samples, including tissue and biological fluid (i.e., blood) collection, processing and accurately recording data associated with samples and research. (15%)Record accurately, the results of experiments using software, such as Graphpad Prism, or Excel. (15%)Maintain detailed and organized records of experiments, protocols and procedures, and laboratory equipment utilized in experiments and the collected data. Organize shipment of samples from or to the laboratory. Maintain certification and servicing of laboratory equipment. (10%)Maintain inventory and order general laboratory supplies. (10%)


    Prepare solutions, buffers, and media for use in experiments as needed. (5%)Perform other assigned duties. Interact with the administrative office or other departments for issues regarding safety, budget, purchase orders and department organization. (<1%)


Department: Frequent contact with supervisor to discuss research and maintain workflow. Frequent contact with lab colleagues to discuss research and maintain workflow.

University: Occasional contact with other departments to share information.

External: Occasional contact with vendors to exchange information.

Students: Occasional Contact with student employees to exchange information.


This position has no direct supervision of staff employees.


Education/Experience: Bachelor’s degree in science and 0 to 1 year of experience or Associate's degree in an approved biotechnology program and 0 to 2 years of experience required.


    Experience with proper animal handling and husbandry.Familiarity with safe handling of biohazardous materials (human blood and body fluids); and knowledge of safe handling practices for laboratory chemicals.Experience with basic laboratory equipment (centrifuge, light microscopes, balances, pH meter, incubators, etc.) and ability to learn new techniques and procedures as needed.Ability to closely follow established protocols or laboratory procedures and request clarification if necessaryExceptional organizational skills in record-keeping with ability to organize, and accurately document data. Must have the ability to maintain meticulous, complete, and easily retrievable laboratory and clinical data.Verbal and written communication skills to be effective in communicating and interacting with a diverse group of people within a laboratory setting and a hospital setting. Ability to interact with colleagues, supervisors, and patients face to face.Experience in use of computers and software including MS Word, Excel, PowerPoint, and Outlook.Must demonstrate effective time management skills and ability to meet consistent attendance.Must demonstrate compliance with university animal research and care (ARC) policies and procedures and compliance to regulations of the Animal Welfare Act, Public Health Service Policy, AAALAC guidelines and other applicable regulatory guidelines.Must demonstrate compassion for animals within university facilities and dedication to the Animal Resource Center’s mission. Must handle animals with care and respect at all times.Previous experience working with animals preferred.Ability to work with sensitive information and maintain confidentiality.Ability to meet consistent attendance.

General laboratory and office environments. May have exposure to hazards. Frequently required to use appropriate gloves and personal protective equipment. In rare cases, may be requested to work overtime and weekends for experiments. The research assistant will receive proper biohazard and general lab safety training, as well as training for lab specific safety measures.

Case Western Reserve University's animal facilities are accredited by the Association for the Assessment and Accreditation of Laboratory Animal Care (AAALAC) and is managed according to the "Guide for the Care and Use of Laboratory Animals” appropriate Federal Animal Welfare Regulations, and the Public Health Service “Policy on the Humane Care and Use of Laboratory Animals." This position, and all animal research personnel, are subject to internal compliance to SOM Animal Resource Center Standard Operating Procedures and to compliance regulations of the Animal Welfare Act, Public Health Service Policy, AAALAC guidelines, the State of Ohio Veterinary Practice Act, Federal Drug Enforcement Administration regulatory guidelines, US Food and Drug Administration Center for Veterinary Medicine regulations and other applicable regulatory guidelines.

Diversity Statement

In employment, as in education, Case Western Reserve University is committed to Equal Opportunity and Diversity. Women, veterans, members of underrepresented minority groups, and individuals with disabilities are encouraged to apply.


Reasonable Accommodations

Case Western Reserve University provides reasonable accommodations to applicants with disabilities. Applicants requiring a reasonable accommodation for any part of the application and hiring process should contact the Office of Equity at 216-368-3066 to request a reasonable accommodation. Determinations as to granting reasonable accommodations for any applicant will be made on a case-by-case basis.



Working at Case Western Reserve University

Case Western Reserve University is among the nation's leading research institutions. Founded in 1826 and shaped by the unique merger of the Case Institute of Technology and Western Reserve University, Case Western Reserve is distinguished by its strengths in educationresearch, service and experiential learning. Located in Cleveland's University Circle, we offer nationally recognized programs in the arts and sciencesdental medicineengineeringlawmanagementmedicinenursing and social sciences.

Student enrollment exceeds 9,800 students, forty percent of whom are undergraduatesFacultyand students hail from more than 90 countries, with academic interests that reach every region of the world. Case Western Reserve, with the support of individuals, corporations and foundations, aids nearly 100 designated research centers.

As a service-oriented institution dedicated to civic leadership, Case Western Reserve seeks individually and collectively to prepare our students to improve the human condition and to direct the benefits of discovery toward a better society. This effort is not limited to the university's classrooms, laboratories, librariesresidence halls and athletic fields, but includes partnerships with many other institutions. We build these partnerships believing that our ability to improve the human condition should begin in our own community.

Case Western Reserve University remains Ohio's top-ranked school among the nation's premier national universities, as ranked by U.S. News & World Report and is the only Ohio institution ranked in the top 50 nationally. We promote a culture of inquiry marked by rigor, creativity, curiosity, innovation, respect, sensitivity and open communication of ideas.

The university supports interdisciplinary partnerships in education and research with numerous faculty holding joint appointments in more than one Case Western Reserve school or department, as well as at neighboring institutions. These relationships launched many of the unique pairings of science, business and liberal arts into the centers and programs that enhance the undergraduate and graduate experience at the university. Our dual degree programs enrich the educational experience for those students who choose to balance the technical requirements of engineering or the sciences with a strong interest in the humanities.

With more than $375 million in research funding annually, the university attracts outstanding undergraduate and graduate students along with renowned faculty whose research has made significant contributions to the way we live and work. Case Western Reserve counts 15 Nobel laureates among our alumni and current and former faculty, including the first American scientist to ever receive the prize.

Our students' experiences in cultural institutions, clinics, social service agencies and industry are not viewed as “extra-curricular,” but create the learning experience that defines a Case Western Reserve education. The university's service programs in the Cleveland Municipal School District have impacted more than 145,000 students with more than 43 signature programs. The university has launched more than 580 community partnerships on the local, national and international levels. Annually the university sponsors Case for Community Day, an event where hundreds of Case Western Reserve employees and students lend their time and talent to targeted community development projects in the Greater Cleveland area.

Our alumni number more than 110,000 and constitute a “who's who” of every profession. Alumni represent one of the university's strongest resources, playing a vital role in campus life through their work as advisors, mentors, friends and advocates.

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