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Research Assistant 1

Case Western Reserve University
Case Main Campus

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Academic Affairs, Research Staff & Technicians
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Job Details

Job Title: Research Assistant 1
Location: Case Main Campus
Regular/Temporary: Regular
Full/Part Time: Full-Time
Job ID: 8864

Working under moderate supervision, the Research Assistant 1 will perform research work and support scientists by performing standard molecular techniques (RNA extraction, qPCR, protein analysis by Western blotting, immunofluorescence, or immunohistochemistry), culturing cells and assessing tumor growth in animals. The research assistant will also collect, verify, record, and compile data and information related to the ongoing research carried out in the lab. The research assistant will be responsible for general laboratory maintenance. This position will work with animals.


    Perform research work in medical and related technical areas involves use of lab skills. Perform research on human and murine cells treated with cancer therapies, biological substances (growth factors, cytokines, chemokines), or viruses to genetically manipulate the cells in vitro (30%). Perform research using animals in vivo to model cancer development and therapy. Perform research on human and murine cells transplanted into animals that will be treated with cancer therapies and biological substances (growth factors, cytokines, chemokines) to test response to therapy (10%). Conduct analysis of samples collected from in vitro and in vivo studies, including common molecular biology techniques to assess how cells and tissues respond to treatment or genetic manipulation. Techniques commonly used include RNA extraction and qPCR, protein analysis by Western blotting, immunofluorescence, immunohistochemistry, and flow cytometry (22%).Record results of experiments. Collect and record cell growth or tumor growth over time by counting, measuring, and using bioluminescence procedures. Quantify target protein or gene expression using statistical methods. Maintain laboratory manuals. (17%). Order laboratory supplies. Place orders through university channels or through direct contact with vendors (6%).Maintain test equipment utilized in experiments. Make reagents stocks and solutions for lab use. Organize lab reagents (plasmids and reagents in freezers/refrigerators). Test cell and organize cell lines in liquid nitrogen stocks (6%). Manage research waste through university protocols (6%).


Perform other duties as assigned. (3%)


Department: Continuous contact with supervisor and lab members to discuss research and maintain workflow and order supplies.

University: Infrequent contact with other departments to share information and collaborate on projects. Interaction with regulatory components (EHS, IACUC, IBC, IRB).

External: Infrequent contact with vendors to procure supplies.

Students: Continuous contact with graduate students within the laboratory to provide technical assistance, to gather information for ordering of supplies, and to update policies and procedures manuals.


This position has no direct supervision of staff employees.


Education/Experience: Bachelor’s degree in science and 0 to 1 year of experience or Associate's degree in an approved biotechnology program and 0 to 2 years of experience required.


    Has knowledge of commonly-used concepts, practices, and procedures within the field of molecular and cellular biology; experience with the field of cancer research preferred. Relies on instructions and pre-established guidelines to perform the functions of the job. Ability to operate laboratory equipment (electrophoresis equipment, PCR machine, centrifuges, microscopes, tissue culture hood).Ability to meet consistent attendance.Ability to interact with colleagues and supervisors face-to-face.Must demonstrate compliance with university animal research and care (ARC) policies and procedures and compliance to regulations of the Animal Welfare Act, Public Health Service Policy, AAALAC guidelines and other applicable regulatory guidelines.Must demonstrate compassion for animals within university facilities and dedication to the Animal Resource Center’s mission. Must handle animals with care and respect at all times.Strong organization skills and good habit of maintaining a clean lab working environment; demonstrate attention to detail and accuracy, time management skillsProfessional and effective verbal and written communication skills and good interpersonal skills with the ability to work and communicate with various individuals.Must be highly motivated, responsible, dependable and a self-starter. Must have the ability to maintain meticulous, complete, and easily retrievable laboratory data.Must have the ability to willingly learn new techniques and procedures as needed, follow established protocols or laboratory procedures and request clarification if necessary.


General laboratory environment. The employee will be exposed to blood-borne pathogens and chemicals. Employee will need to wear appropriate protective equipment such as gloves, coat, and eyewear. Working conditions will require working at the bench in a molecular genetics/ biology laboratory, working with mice and other animal models in the laboratory and in the animal facility.

Case Western Reserve University's animal facilities are accredited by the Association for the Assessment and Accreditation of Laboratory Animal Care (AAALAC) and is managed according to the "Guide for the Care and Use of Laboratory Animals” appropriate Federal Animal Welfare Regulations, and the Public Health Service “Policy on the Humane Care and Use of Laboratory Animals." This position, and all animal research personnel, are subject to internal compliance to SOM Animal Resource Center Standard Operating Procedures and to compliance regulations of the Animal Welfare Act, Public Health Service Policy, AAALAC guidelines, the State of Ohio Veterinary Practice Act, Federal Drug Enforcement Administration regulatory guidelines, US Food and Drug Administration Center for Veterinary Medicine regulations and other applicable regulatory guidelines.

Diversity Statement

In employment, as in education, Case Western Reserve University is committed to Equal Opportunity and Diversity. Women, veterans, members of underrepresented minority groups, and individuals with disabilities are encouraged to apply.


Reasonable Accommodations

Case Western Reserve University provides reasonable accommodations to applicants with disabilities. Applicants requiring a reasonable accommodation for any part of the application and hiring process should contact the Office of Equity at 216-368-3066 to request a reasonable accommodation. Determinations as to granting reasonable accommodations for any applicant will be made on a case-by-case basis.



Working at Case Western Reserve University

Case Western Reserve University is among the nation's leading research institutions. Founded in 1826 and shaped by the unique merger of the Case Institute of Technology and Western Reserve University, Case Western Reserve is distinguished by its strengths in educationresearch, service and experiential learning. Located in Cleveland's University Circle, we offer nationally recognized programs in the arts and sciencesdental medicineengineeringlawmanagementmedicinenursing and social sciences.

Student enrollment exceeds 9,800 students, forty percent of whom are undergraduatesFacultyand students hail from more than 90 countries, with academic interests that reach every region of the world. Case Western Reserve, with the support of individuals, corporations and foundations, aids nearly 100 designated research centers.

As a service-oriented institution dedicated to civic leadership, Case Western Reserve seeks individually and collectively to prepare our students to improve the human condition and to direct the benefits of discovery toward a better society. This effort is not limited to the university's classrooms, laboratories, librariesresidence halls and athletic fields, but includes partnerships with many other institutions. We build these partnerships believing that our ability to improve the human condition should begin in our own community.

Case Western Reserve University remains Ohio's top-ranked school among the nation's premier national universities, as ranked by U.S. News & World Report and is the only Ohio institution ranked in the top 50 nationally. We promote a culture of inquiry marked by rigor, creativity, curiosity, innovation, respect, sensitivity and open communication of ideas.

The university supports interdisciplinary partnerships in education and research with numerous faculty holding joint appointments in more than one Case Western Reserve school or department, as well as at neighboring institutions. These relationships launched many of the unique pairings of science, business and liberal arts into the centers and programs that enhance the undergraduate and graduate experience at the university. Our dual degree programs enrich the educational experience for those students who choose to balance the technical requirements of engineering or the sciences with a strong interest in the humanities.

With more than $375 million in research funding annually, the university attracts outstanding undergraduate and graduate students along with renowned faculty whose research has made significant contributions to the way we live and work. Case Western Reserve counts 15 Nobel laureates among our alumni and current and former faculty, including the first American scientist to ever receive the prize.

Our students' experiences in cultural institutions, clinics, social service agencies and industry are not viewed as “extra-curricular,” but create the learning experience that defines a Case Western Reserve education. The university's service programs in the Cleveland Municipal School District have impacted more than 145,000 students with more than 43 signature programs. The university has launched more than 580 community partnerships on the local, national and international levels. Annually the university sponsors Case for Community Day, an event where hundreds of Case Western Reserve employees and students lend their time and talent to targeted community development projects in the Greater Cleveland area.

Our alumni number more than 110,000 and constitute a “who's who” of every profession. Alumni represent one of the university's strongest resources, playing a vital role in campus life through their work as advisors, mentors, friends and advocates.

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