Postdoctoral Research Associate
Job location: Charlottesville, VA
Employment Type: Full-time
Posted data: 2021-04-30
The Department of Pediatrics, Division of Pediatric Hematology/Oncology, at the University of Virginia is seeking a Postdoctoral Research Associate. The position carries out research studies in the laboratory of Dr. Daniel "Trey" Lee, MD, a pioneer in the use of Chimeric Antigen Receptor (CAR) T cells for the treatment of pediatric malignancies (Lee DW et al, Lancet 2015, PMID: 25319501, 29155426, 29712574, 30592986). The focus of the Lee Lab is to develop and rapidly translate new CAR T cell therapies for childhood and adult malignancies including leukemia, medulloblastoma, diffuse intrinsic pontine glioma, and glioblastoma among others to the clinic through investigator-initiated clinical trials at UVA using our newly opened Center for Human Therapeutics, a cGMP facility for the manufacturing of clinical-grade cellular products. We also aim to improve on the safety of CAR T cell therapies via development of novel safety and control mechanisms.
Duties & Responsibilities: The successful candidate is expected to work both independently and collaboratively on several projects. Duties include: designing and setting up experiments; knowing, understanding, and being able to perform necessary research techniques; and analyzing, evaluating, and presenting data with the goal of publishing and securing extramural funding. Preparation of manuscripts and grant applications are expected. The successful candidate will be expected to remain current with appropriate research literature, participate in lab meetings and relevant cancer and immunology seminars and journal clubs, and conduct general lab functions. The Research Associate will be held to the highest expectations in the ethical conduct of scientific research.
Position Qualifications: Necessary qualifications include a Ph.D. in Cancer Biology, Immunology, Molecular Biology, or a related field in hand at the date of hire with a strong publication record in peer-reviewed journals in these areas. Candidates must possess a strong work ethic with a high level of self-motivation, the ability to work both independently and collaboratively with a willingness to work in a highly interactive and collegial group, and excellent written and oral communication skills. The successful candidate must have extensive experience with tissue culture (including primary cell culture), flow cytometry, cell-based assays including cytotoxicity assays, and the capacity to work with infectious agents under BSL-2 conditions and be proficient in basic mouse methodologies and surgeries. Highly preferred qualifications include experience with human immunology and/or T cell biology, molecular biology, cell signaling, molecular cloning and transfection, and lab work involving xenograft models of human disease.
Postdoctoral employment is temporary and is normally limited to an individual who has been awarded a Ph.D. or equivalent doctorate within the previous five years and who will be involved in full-time research or scholarship at the University. Employment as a Postdoctoral Research Associate is viewed as training and is preparatory for a full-time academic or research career, is supervised by a senior scholar, and allows the appointee to publish the results of his/her research or scholarship during the training period.
This is a restricted position. Continuation is dependent on funding and satisfactory performance.
The position will remain open until filled.
For additional information, please contact Dr. Lee, Department of Pediatrics, at firstname.lastname@example.org
EXTERNAL APPLICANTS: please apply through Workday at the following URL, https://uva.wd1.myworkdayjobs.com/UVAJobs , and search for requisition #R0024130. Complete an application online and attach a cover letter, CV/resume, and contact information for three references (name, email address, telephone number, address). The successful candidate will pass a criminal background check. Please note that multiple documents can be uploaded in the box.
INTERNAL UVA APPLICANTS: please apply through your Workday Home page, search “Find Jobs”, and search for requisition #R0024130. Complete an application online and attach a cover letter, CV/resume, and contact information for three references (name, email address, telephone number, address). The successful candidate will pass a criminal background check. Please note that multiple documents can be uploaded in the box.
The University of Virginia, including the UVA Health System which represents the UVA Medical Center, Schools of Medicine and Nursing, UVA Physician’s Group and the Claude Moore Health Sciences Library, are fundamentally committed to the diversity of our faculty and staff. We believe diversity is excellence expressing itself through every person's perspectives and lived experiences. We are equal opportunity and affirmative action employers. All qualified applicants will receive consideration for employment without regard to age, color, disability, gender identity or expression, marital status, national or ethnic origin, political affiliation, race, religion, sex (including pregnancy), sexual orientation, veteran status, and family medical or genetic information.