Research Associate

Job description

Description
University of Colorado School of Medicine

University of Colorado | CU Anschutz Medical Campus

School of Medicine, Department of Pediatrics

Section of Hematology, Oncology, and Bone Marrow Transplantataion Research

Research Associate

Position #00613155– Requisition #21010

* Applications are accepted electronically ONLY at www.cu.edu/cu-careers *

The University of Colorado Anschutz Medical Campus seeks individuals with demonstrated commitment to creating an inclusive learning and working environment.  We value the ability to engage effectively with students, faculty and staff of diverse backgrounds.

The Department of Pediatrics, Section of Hematology, Oncology, and Bone Marrow Transplantataion Research has an opening for a full-time Research Associate position. 

Nature of Work:

  • This position is part of an exciting research program to understand the molecular mechanisms of brain tumor biology. The laboratory uses cellular and mouse models to recapitulate the human disease, with an emphasis on epigenetics in medulloblastoma. We are looking for a PhD scientist who is interested in studying the role of histone modifications in brain tumors using standard molecular biology techniques and genome wide analysis such as ChIP-Seq, and array based expression profiling or RNA-Seq. We are also looking for experience with in vivo models of brain development/disease/tumors. Knowledge of epigenetic regulation and mechanism of gene expression in stem cell specification and differentiation is highly desired.
 

The University of Colorado Anschutz Medical Campus is a public education, clinical and research facility serving 4,500 students, and a world-class medical destination at the forefront of life-changing science, medicine, and healthcare. CU Anschutz offers more than 42 highly rated degree programs through 6 schools and colleges, and receives over $500 million in research awards each year. We are the single largest health professions education provider in Colorado, awarding nearly 1,450 degrees annually. Powered by our award-winning faculty, renowned researchers and a reputation for academic excellence, the CU Anschutz Medical Campus drives innovation from the classroom to the laboratory to the delivery of unparalleled patient care. Read CU Anschutz Quick Facts here.

Position Emphasis:

  • Cell culture of tumor cells. 15%
  • Transfection of histone modifying enzymes into cells. 15%
  • Measuring consequences of Histone modifications by western blotting, qPCR, Chip-Seq and gene expression profiling. 15%
  • Evaluating phenotypic consequences of histone modifications by measuring cell proliferation, cell self-renewal, cell death and senescence using standard cell biology techniques such as flow cytometry, cell culture, and
  • immunohistochemistry. 15%
  • Creating tumors in mice and evaluating the consequences of alternations in histone modifications on tumor development and growth. 10%
  • Set up mouse breeding/genotypying and maintain mouse colonies. 10%
  • Independently performed lab experiments. 5%
  • Collection and analysis of all data. 5%
  • Synthesis of data presenting data at lab meetings, reviewing literature relevant to project and writing of manuscript. 5%
  • Maintain accurate and current laboratory notebook including all experimental details. 5%
PLEASE NOTE: Candidates will be responsible for travel expenses related to the interview process and any relocation expenses, if applicable.

Salary and Benefits:

The hiring rate (or budgeted rate) for this position has been established at $58,000.

The above salary rate represents the University’s good faith and reasonable estimate of the rate at the time of posting.

This position is not eligible for overtime compensation.

The University of Colorado offers a full benefits package. Information on University benefits programs, including eligibility, is located at Employee Services.

 

University of Colorado Denver | Anschutz Medical Campus is dedicated to ensuring a safe and secure environment for our faculty, staff, students and visitors. To assist in achieving that goal, we conduct background checks for all new employees prior to their employment.

 

The Immigration Reform and Control Act requires that verification of employment eligibility be documented for all new employees by the end of the third day of work. Alternative formats of this ad are available upon request for persons with disabilities.

 

Your total compensation goes beyond the number on your paycheck. The University of Colorado provides generous leave, health plans and retirement contributions that add to your bottom line.

 

Benefits: https://www.cu.edu/employee-services/benefits.

Total Compensation Calculator: https://www.cu.edu/employee-services/total-compensation

 

Diversity and Equity:

 

Please click here for information on disability accommodations: https://www1.ucdenver.edu/offices/human-resources/employee-relations-performance/ada-compliance

 

Office of Equity: https://www1.ucdenver.edu/offices/equity

 

The University of Colorado Denver | Anschutz Medical Campus is committed to recruiting and supporting a diverse student body, faculty and administrative staff. The university strives to promote a culture of inclusiveness, respect, communication and understanding. We encourage applications from women, ethnic minorities, persons with disabilities and all veterans. The University of Colorado is committed to diversity and equality in education and employment.

 



Qualifications
Minimum Qualifications:

  • Graduation from an accredited university with a PhD in Genetics, Cancer Biology, Biochemistry, Molecular Biology, or related field.
  • Minimum of 3 years of Cancer/Molecular Biology lab experience.
Applicants must meet minimum qualifications at the time of hire.

Conditions of Employment:

  • Must be willing and able to pass a national criminal background check.
Preferred Qualifications:

  • Prior experience with murine cancer or brain disease models.
  • Experience with stem cell biology and relevant assays (flow cytometric analysis and flow sorting of stem or progenitor population.
  • Prior experience in chromatin biology.
Competencies:

  • Ability to function autonomously but exercise sound judgment in seeking appropriate supervision.
  • Skilled in communicating effectively and facilitating group processes.
  • Ability to establish and maintain effective working relationships with sponsors, researchers, and other team members.
  • Comply with all standard operating procedures and quality control systems per the University of Colorado policy.
  • Comply with any laboratory duties assigned by the PI.
  • Knowledgeable of epigenetic regulation and mechanism of gene expression in stem cell specification.
  • Demonstrates the proficiency in computer software, equipment operation, or research technical skills.
  • Excellent communication skills in English.


Job Category: Faculty
Primary Location: Aurora
Schedule: Full-time
Posting Date: Apr 28, 2021
Unposting Date: May 4, 2021, 5:59:00 AM

 

 

 

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Job No:
Posted: 4/30/2021
Application Due: 5/5/2021
Work Type: Full Time
Salary: