University of Colorado – School of Medicine
The University of Colorado Denver l Anschutz Medical Campus seeks individuals with demonstrated commitment to creating an inclusive learning and working environment. We value the ability to engage effectively with students, faculty and staff of diverse backgrounds.Nature of WorkThis position involves intensive investigation of the biophysical properties of telomeres, including their supercoil state, their chromatin composition and arrangement, and any propensity to form condensates in vitro and in vivo. This research involves extensive molecular genetic manipulation of fission yeast, biophysical analysis of DNA molecules purified from cells as well as chromatin reconstituted in vitro, and development and implementation of genomewide approaches to studying torsional state throughout the genome. Professional FieldBiochemistry/biophysics/molecular biology/genetics/cell biologyExamples of Work PerformedThe duties and responsibilities of the position include:30% of time: Contribute to conceptual and experimental design for project, solve experimental problems, plan each approach from start to finish. Analyze and interpret data, in consultation with PI. Learn, understand and contribute to all other colleagues’ projects in the lab. Read relevant literature. Participate actively in lab and departmental meetings. Present research and learn about others’ research in seminars and posters at national and international conferences. Plan, prepare and revise manuscripts in consultation with PI. 70% of time: Fission yeast strain construction and husbandry; mammalian cell culture. Genetic manipulation of fission yeast; cell synchronization. Biochemical and biophysical analysis of DNA isolated from cells including chloroquine gel analysis, southern blots, analysis of psoralen crosslinking, analysis by enzyme sensitivity. Purification of telomere proteins, reconstitution of nucleosomes, investigation of phase separation properties of telomeric chromatin. Supervision ReceivedThe Research Associate reports to the Professor and Chair of Biochemistry and Molecular Genetics, Julia Cooper. Supervision ExercisedThe Research Associate will not supervise other employees.Salary RangeThe salary range (or hiring range) for this position has been established at $83,000 to $86,000. The salary of the finalist(s) selected for this role will be set based on a variety of factors, including but not limited to, internal equity, experience, education, specialty and training.The above salary range (or hiring range) represents the University’s good faith and reasonable estimate of the range of possible compensation at the time of posting.The University of Colorado offers a full benefits package. Information on University benefits programs, including eligibility, is located at Employee Services. University of Colorado Denver | Anschutz Medical Campus is dedicated to ensuring a safe and secure environment for our faculty, staff, students and visitors. To assist in achieving that goal, we conduct background checks for all new employees prior to their employment. The Immigration Reform and Control Act requires that verification of employment eligibility be documented for all new employees by the end of the third day of work. Alternative formats of this ad are available upon request for persons with disabilities. Your total compensation goes beyond the number on your paycheck. The University of Colorado provides generous leave, health plans and retirement contributions that add to your bottom line. Benefits: https://www.cu.edu/employee-services/benefits.Total Compensation Calculator: https://www.cu.edu/employee-services/total-compensation Diversity and Equity: Please click here for information on disability accommodations: https://www1.ucdenver.edu/offices/human-resources/employee-relations-performance/ada-compliance Office of Equity: https://www1.ucdenver.edu/offices/equity The University of Colorado Denver | Anschutz Medical Campus is committed to recruiting and supporting a diverse student body, faculty and administrative staff. The university strives to promote a culture of inclusiveness, respect, communication and understanding. We encourage applications from women, ethnic minorities, persons with disabilities and all veterans. The University of Colorado is committed to diversity and equality in education and employment.
Minimum QualificationsPh.D. in molecular biology, biochemistry, biophysics or a related field. At least 4 years experience and deep understanding of chromosome biology, yeast genetics and biochemistry. Applicants must meet minimum qualifications at the time of hire. Preferred QualificationsExpertise in protein purification and analysis of supercoil isomers. Expertise in genomewide and bioinformatic analysis. Ample demonstration of experimental rigor and innovativeness. Excellent communication skills.
Job Category: Faculty
Primary Location: Aurora
Posting Date: Apr 27, 2021
Unposting Date: May 2, 2021, 11:59:00 PM