Assistant Project Scientist in Cardiology

Job description

Assistant Project Scientist in Cardiology
University of California Los Angeles

Requisition Number: JPF06366

The Division of Cardiology in the Department of Medicine at the David Geffen School of Medicine at UCLA invites applications for a position at the level of Assistant Project Scientist in the laboratory of Drs. Srinivasa T. Reddy and Alan M. Fogelman. The main focus of research is to identify novel pathways and mechanisms for the treatment of chronic inflammatory diseases including atherosclerosis, inflammatory bowel disease, and cancer. The candidate will spend majority of time in research and is expected to present their work at laboratory, departmental, and scientific conferences.

Requirements: An MD or PhD or MD/PhD is required with 3+ years of postdoctoral fellowship. Must have extensive research experience and a strong publication record. Candidates with a strong background in studies of the microbiota, molecular immunology and/or molecular biology and or related disciplines are strongly encouraged to apply.

The project is focused on dietary regulation of the mucus layer in the small intestine, which provides the interface between the microbiota and enterocytes. The project will use in vivo, and ex vivo models with primary cells and gut tissue explants to determine mechanisms by which apoA-I mimetic peptides alter host cellular responses (involving bioactive lipids, immune and epithelial cells) and protect against the development of chronic inflammatory diseases. The proposed research is expected to lead to studies of the clinical efficacy of oral apoA-I mimetic peptides in human inflammatory diseases. The overall project leverages multidisciplinary expertise in cardiovascular disease, inflammation, oxidative stress, and intestinal biology.

The candidate is expected to be independent (or require minimal training/supervision) in performing essential experimental techniques for the laboratory including cell culture, tissue processing (with a focus on intestinal tissue), cell and molecular biology assays and mass spectrometry. The candidate is expected to be comfortable following biosafety procedures related to working with biospecimens (blood, tissues, cells).

The Assistant Project Scientist is expected to supervise lab personnel (SRAs). As needed, the candidate will perform literature searches to gather information relating to current research projects. The candidate will organize data for easy access and may perform any special projects as assigned by the Principal Investigator(s). The individual will learn new laboratory procedures and techniques as needed.

Responsibilities - Ideal candidates will be expected to:

  • Lead existing research projects with regards to design, execution and analysis of experiments, guidance of technicians to complete assigned work within specific timeframe.
  • Establish independent research projects, present at scientific meetings, write peer-reviewed publications
  • Participate in multidisciplinary research collaborations
  • Contribute to training/supervision of students and technicians in the lab
  • Oversee the maintenance of the laboratory.

    To apply, please visit:

    The University of California is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, age or protected veteran status. For the complete University of California nondiscrimination and affirmative action policy, see: UC Nondiscrimination & Affirmative Action Policy,





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    Job No:
    Posted: 4/27/2021
    Application Due: 4/27/2033
    Work Type: Full Time