Research Assistant 2
Job Title: Research Assistant 2
Location: Case Main Campus
Full/Part Time: Full-Time
Job ID: 8789
Job Description POSITION OBJECTIVE
- Plan and carry out research projects that characterize the roles of myofilament contractile proteins in the regulation of cardiac muscle contraction. (25%) Manage animal resources used in experiments by keeping detailed records of animal inventory, setting up and checking breeding pairs for litters and separating cages at time of weaning. (10%)Conduct in vivo gene therapy experiments using intravenous and retro-orbital injection of AAV9 vectors in mice. (15%)Conduct a wide range of biochemical and functional studies of cardiac mechanics including: gel electrophoresis, gel purification, western blotting, kinase experiments, immunohistochemistry, expression and purification of recombinant proteins, and small animal echocardiography. (20%)Collect, organize and analyze research data for presentation in laboratory meetings. (15%)May assist in developing more efficient gene therapy and biochemical techniques. (5%)
- Oversee inventory and standard operating procedures. Maintain equipment, prepare buffer/media/reagents, and dispose biohazardous waste. Maintain lab records. Train new staff; direct the work of students. (5%)Perform other duties as assigned. (5%)
- Knowledge of commonly used concepts, practices and procedures in chemistry, physics, biochemistry and molecular/cellular biology and in vivo cardiovascular function. Prior experience with cell culture, protein expression/purification, confocal microscopy, small animal surgery, muscle mechanics experiments. Previous experience working with animals preferred. Must demonstrate compliance with Case Western Reserve University animal research and care (ARC) policies and procedures and compliance to regulations of the Animal Welfare Act, Public Health Service Policy, AAALAC guidelines and other applicable regulatory guidelines. Must demonstrate compassion for animals within Case Western Reserve University facilities and dedication to the Animal Resource Center’s mission. Must handle animals with care and respect at all times.Must be able and willing to learn new techniques, procedures, processes, and computer gear to protect the health of the animals.Ability to follow instructions and pre-established guidelines to perform the functions of the job with minimal supervision.Strong organization skills and maintenance of laboratory records, with attention to scientific detail.Ability to multi-task, prioritize and give attention to detail in order to complete tasks and meet deadlines.Ability to effectively operate basic molecular and cellular biology laboratory equipment. Ability to problem solve effectively and assist in the development and implementation of alternative solutions as needed. Must demonstrate good judgment and logical decision making.Ability to work effectively, both independently and collaboratively within a team.Technical competence with software programs such as Microsoft Office (Word, Excel, and PowerPoint) and scientific graphics packages (such as Origin) is strongly preferred. Ability to learn and apply software programs and applications as needed.Ability to perform various molecular biology techniques and muscle mechanics experiments.Ability to learn and apply new techniques, ideas, processes, policies, functions, etc. Must be highly motivated and a self-starter.Ability to conform to shifting priorities, demands and timelines. Must be flexible in order to respond to project adjustments and alterations promptly and efficiently. Must be able to adapt to varying workloads and respond appropriately to stressful situations.Excellent verbal and written communication skills; good interpersonal skills with the ability to interact with colleagues, supervisors and customers face to face.Ability to follow through on assigned projects and provide timely follow-up as needed.Ability to meet consistent attendance.
In employment, as in education, Case Western Reserve University is committed to Equal Opportunity and Diversity. Women, veterans, members of underrepresented minority groups, and individuals with disabilities are encouraged to apply.
Case Western Reserve University provides reasonable accommodations to applicants with disabilities. Applicants requiring a reasonable accommodation for any part of the application and hiring process should contact the Office of Equity at 216-368-3066 to request a reasonable accommodation. Determinations as to granting reasonable accommodations for any applicant will be made on a case-by-case basis.