Life Science Professional 1
Life Science Professional 1🔍School of Medicine, Stanford, California, United States📁Research📅Apr 23, 2021 Post Date📅89298 Requisition #Stanford University is seeking a Life Science Research Professional 1 to perform basic functions and activities involved in defined research projects, and independently conduct and analyze experiments.About the lab: https://vanrechemlab.comThe Van Rechem lab long-term interest lies in understanding the impact chromatin modifiers have on disease development and progression so that more optimal therapeutic opportunities can be achieved. We explore the direct molecular impact of chromatin-modifying enzymes during cell cycle progression and characterizes the unappreciated and unconventional roles that these chromatin factors have on cytoplasmic function such as protein synthesis. By gaining molecular understanding into the mechanism of action of chromatin modifiers in normal and pathological cells, we will improve our basic knowledge and provide needed insights into new potential targeted therapies in diseases. Position:We are seeking a Life Science Research Professional 1 to help support research related to the roles of chromatin remodelers in protein synthesis and their relationship to nuclear functions. Specifically, the project involves learning, designing, and executing molecular assays to study the transcription and translation of specific RNAs and the relationship between such functions in different subcellular compartments, under normal conditions and upon cancer alterations. The LSRP will work in close collaboration with a post-doc with the possibility to evolve toward a more independent role and a defined project under this broad research area. This work is expected to lead to publication(s). Skills learned can prepare the researcher for a future in graduate school or as a lab manager in the research industry, among other possibilities. The desired candidate is collaborative, detail-oriented, and conscientious, with excellent written/oral communication and interpersonal skills. Under the supervision of the principal investigator and a postdoc, duties include participation in research projects and assay development (stable cell lines by CRISPR/Cas9, protein synthesis methods such as polysome profiling, RNA transcription methods such as RNA-seq, NGS library preparation…), data collection, and assistance with data analysis and manuscripts. Duties include: Stanford University is seeking a Life Science Research Professional 1 to perform basic functions and activities involved in defined research projects, and independently conduct and analyze experiments.
- Plan approach to experiments in support of research projects in lab and/or field based on knowledge of scientific theory. Independently conduct experiments; maintain detailed records of experiments and outcomes. Apply the theories and methods of a life science discipline to interpret and perform analyses of experiment results; offer suggestions regarding modifications to procedures and protocols in collaboration with senior researcher.Review literature on an ongoing basis to remain current with new procedures and apply learnings to related research. Contribute to publication of findings as needed. Participate in the preparation of written documents, including procedures, presentations, and proposals. Help with general lab maintenance as needed; maintain lab stock, manage chemical inventory and safety records, and provide general lab support as needed.Assist with orientation and training of new staff or students on lab procedures or techniques.
- Bachelor’s degree in biology, biochemistry or a related area.
- Knowledge and experience in the following fields: molecular biology and biochemistry such as CRISPR/Cas9, mammalian tissue culture, protein and RNA-related methods, etc…
- Good communication and the ability to perform as part of a team.
- General understanding of scientific principles. Demonstrated performance to use knowledge and skills when needed.Demonstrated ability to apply theoretical knowledge of science principals to problem solve work. Ability to maintain detailed records of experiments and outcomes.General computer skills and ability to quickly learn and master computer programs, databases, and scientific applications.Ability to work under deadlines with general guidance. Excellent organizational skills and demonstrated ability to accurately complete detailed work.
- Frequently stand, walk, twist, bend, stoop, squat, grasp lightly, use fine manipulation, grasp forcefully, perform desk-based computer tasks, use telephone, write by hand, lift, carry, push and pull objects weighing over 40 pounds. Occasionally sit, kneel, crawl, reach and work above shoulders, sort and file paperwork or parts. Rarely climb, scrub, sweep, mop, chop and mix or operate hand and foot controls. Must have correctible vision to perform duties of the job.Ability to bend, squat, kneel, stand, reach above shoulder level, and move on hard surfaces for up to eight hours.Ability to lift heavy objects weighing up to 50 pounds.Ability to work in a dusty, dirty, and odorous environment.Position may require repetitive motion.
- May require working in close proximity to blood borne pathogens.May require work in an environment where animals are used for teaching and research.Position may at times require the employee to work with or be in areas where hazardous materials and/or infectious diseases are present. Employee must perform tasks that require the use of personal protective equipment, such as safety glasses and shoes, protective clothing, gloves, and possibly a respirator.
- Schedule: Full-time
- Job Code: 4945
- Employee Status: Regular
- Grade: E
- Requisition ID: 89298