Description

UNIVERSITY OF COLORADO DENVER | ANSCHUTZ MEDICAL CAMPUS
 Department of Dermatology-Gates Center

Research Instructor
Job Code: 00782554

 

The University of Colorado Denver l Anschutz Medical Campus seeks individuals with demonstrated commitment to creating an inclusive learning and working environment.  We value the ability to engage effectively with students, faculty and staff of diverse backgrounds.

The Department of Dermatology, Charles C. Gates Center for Regenerative Medicine has an opening for a full-time (unclassified) Research Instructor position.

The University of Colorado Anschutz Medical Campus is a public education, clinical and research facility serving 4,500 students, and a world-class medical destination at the forefront of life-changing science, medicine, and healthcare. CU Anschutz offers more than 42 highly rated degree programs through 6 schools and colleges and receives over $500 million in research awards each year. We are the single largest health professions education provider in Colorado, awarding nearly 1,450 degrees annually. Powered by our award-winning faculty, renowned researchers and a reputation for academic excellence, the CU Anschutz Medical Campus drives innovation from the classroom to the laboratory to the delivery of unparalleled patient care.

Nature of Work

An Instructor is needed to develop a novel research direction in the area of mitochondrial metabolism and stem cell biology. The successful candidate will study mitochondrial biology during differentiation of human induced Pluripotent Stem Cells (iPSCs) into a variety of somatic cells. The successful applicant will also study changes in mitochondria of human somatic cells during culture-induced senescence, disease-induced senescence, and normal aging. The successful candidate must have strong background in developmental biology, mammalian cell culture, confocal microscopy, including microscopy of subcellular organelles, studying redox signaling using a variety of methods, including the use of chemical or genetically encoded fluorescent reporters, proteomics and analysis of mass spectrometry data with a particular focus on analysis of protein thiol groups.

Duties and Responsibilities
Additional responsibilities will require strong background in molecular biology, cloning, and genetic engineering using the CRISPR/Cas9 system. Together with the Principal Investigator (PI), the successful candidate will participate in the work of the Stem Cell Biobank and Disease Modeling (SCB&DM) Core. The primary focus of the work for the SCB&DM Core will be on genetic engineering projects. The duties will include the design and execution of gene editing strategies in human iPSCs and human primary cell lines and the characterization of genetically modified cells. It is expected that this employee will oversee the overall efficiency of the core facility and communicate with clients on a regular basis. The instructor will also plan the scope of work for timely project fulfillment. The job duties will include supervision of students and research assistants.

The successful candidate is expected to design and execute experiments, write manuscripts, assist the PI in preparing grant applications, perform scientific troubleshooting, data analysis and presentation, write and adhere or modify standard operational procedures (SOP) and conduct oneself in professional, ethical and moral manner at all times. This position requires independent judgment in management of employees, daily operations and in solving non-routine problems. The Instructor is expected to participate in in-class teaching activities of the Department. The adaptation of latest techniques and development of new approaches related to research projects are expected.

Examples of Work Performed

The duties and responsibilities of the position include, but are not limited to:

• Design and execute experiments.
• Advise postdocs and students.
• Manage staff and trainees.
• Supervise students.
• Maintain laboratory manuals including all laboratory protocols, SOPs, and policies.
• Develop and implement competency assessment program for lab staff.
• Complete all UCD required training courses and ensure staff have completed.
• Performs other duties as assigned.
• Perform computer data entry.
• Write manuscripts and part of grant applications.
• Help with SCB&DM core function.
• Prepare samples and perform analysis of proteomics data.
• Prepare samples and perform analysis of microscopy data.
• In classroom teaching of graduate and undergraduate students.

Supervision Received

The Instructor reports to the Principal Investigator, Dr. Igor Kogut, Assistant Professor of Dermatology.

Supervision Exercised

The Instructor will supervise other employees, including Professional Research Assistants. In addition, the Instructor will provide training and mentoring to graduate students and/or postdoctoral fellows.

Salary and Benefits:

The hiring rate (or budgeted rate) for this position has been established at $100,000.

The above salary rate represents the University’s good faith and reasonable estimate of the rate at the time of posting.

The University of Colorado offers a full benefits package. Information on University benefits programs, including eligibility, is located at Employee Services.

University of Colorado Denver | Anschutz Medical Campus is dedicated to ensuring a safe and secure environment for our faculty, staff, students and visitors. To assist in achieving that goal, we conduct background checks for all new employees prior to their employment.

The Immigration Reform and Control Act requires that verification of employment eligibility be documented for all new employees by the end of the third day of work. Alternative formats of this ad are available upon request for persons with disabilities.

Your total compensation goes beyond the number on your paycheck. The University of Colorado provides generous leave, health plans and retirement contributions that add to your bottom line.

Benefits: https://www.cu.edu/employee-services/benefits.

Total Compensation Calculator: https://www.cu.edu/employee-services/total-compensation

Diversity and Equity:

Please click here for information on disability accommodations: http://www.ucdenver.edu/about/departments/HR/jobs/Pages/JobsatCUDenver.aspx 

Office of Equity: https://www1.ucdenver.edu/offices/equity

The University of Colorado Denver | Anschutz Medical Campus is committed to recruiting and supporting a diverse student body, faculty and administrative staff. The university strives to promote a culture of inclusiveness, respect, communication and understanding. We encourage applications from women, ethnic minorities, persons with disabilities and all veterans. The University of Colorado is committed to diversity and equality in education and employment.

Qualifications
Minimum Qualifications

 
• PhD or equivalent in Molecular Biology, Cell Biology or other Biological fields, or a related degree.
• Minimum 4 years of relevant postdoctoral experience in developmental biology, mammalian cell culture, mitochondrial biology, confocal microscopy, proteomics, and genetic engineering.

Preferred Qualifications

 
• 10 years or more of relevant postdoctoral experience.
• Work with human iPSCs
• Light Sheet Microscopy

Applicants must meet minimum qualifications at the time of hire. 

Job Category: Faculty
Primary Location: Aurora
Schedule: Full-time
Posting Date: Apr 7, 2021
Unposting Date: Ongoing