Research Technologist I
Job descriptionJob no: 695955
Work type: Support Staff
Pay Grade: 08
Major Administrative Unit / College: College Of Human Medicine
Department: Translational Neuroscience 40000320
Sub Area: CT- Clerical Tech.
Salary: Salary Commensurate with Experience
Location: Grand Rapids
Categories: Full Time (90-100%), Clerical Technical- CT, Research/Scientific, Union
The Department of Translational Neuroscience at Michigan State University (MSU) is seeking a productive and highly motivated individual to participate in research on the role of striatal pathology in therapy-mediated dysfunction in Parkinson’s disease (PD). The research tech will work 40 hours per week under the guidance of the senior post-doctoral fellow and principle investigator on translational studies in a rat model of PD. Specifically, this project involves examining the ability of AAV-based gene therapy to provide high potency and target-selective mRNA-level silencing of nigral and/or striatal CaV1.3 channels in preventing nigral neuron death and/or ameliorating levodopa-induced dyskinesias. The aim of these studies is to provide an understanding of the functional and molecular consequences associated with this gene modulation, as well as the impact of subject age and sex on functional and molecular readouts. Multi-disciplinary approaches include but are not limited to stereotaxic surgery; animal behavior; brain sectioning; fluorescent immunohistochemistry and in situ hybridization; light and confocal microscopy; stereological and Imaris® data collection. The research tech will also be expected to carry out duties critical for general lab maintenance and function such as assist in reagent supplies, making solutions, as well as data collection. While the candidate must be willing to work as part of a team and participate actively in ongoing research, they must also be capable of working independently while following established protocols.
This position is located in the new state-of-the-art Grand Rapids Research Center at 400 Monroe Ave NW, Grand Rapids, MI 49503.Unit Specific Education/Experience/Skills
Knowledge equivalent to that which normally would be acquired by completing a four-year college degree program in the specific field of research employment or other related field; up to six months of related and progressively more responsible or expansive work experience in basic research techniques in the specific or related field; word processing, spreadsheet; database and/or desktop publishing software; presentation software; or an equivalent combination of education and experience. The job may require the appropriate pesticide applicator's registration/certification and/or experience working with potentially dangerous research animals.Desired Qualifications
Minimum requirements include a Bachelor of Science degree in natural sciences and experience working in a basic science laboratory. The applicant must have excellent interpersonal and communication skills.
Skills desired include a background with microscopy (e.g.: light; confocal experience a benefit), tissue handling and processing (e.g.: immunohistochemistry and/or in situ hybridization), and small animal handling.Equal Employment Opportunity Statement
All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, citizenship, age, disability or protected veteran status.Required Application Materials
Cover letter, CV, and the names and contact information for three referencesWork Hours
STANDARD 8-5Description of End Date
This is a limited term position funded for one year from date of hire with possible extension contingent upon funding renewal.Summary of Health Risks
Work with animals or unfixed animal tissueBidding and Eligibility Ends on 4/13/2021 at 11:55 PM
Advertised: Apr 7, 2021 Eastern Daylight Time
Applications close: Apr 20, 2021 Eastern Daylight Time