Research Associate I

Job description

Overview

GENERAL SUMMARY OF POSITION:  

Under the direction of the Principal Investigator or designee, the Research Associate I performs a variety of complex research experiments.

 

 

Responsibilities

MAJOR RESPONSIBILITIES:

  • Perform complex laboratory experiments
  • Conduct in-depth analysis of research experiments
  • Interpret data, form conclusions, and decide on and plan the next experiments to be done with a high degree of independence
  • Write standard operating procedures, schedule work, analyze data, maintain accurate records, and write reports
  • Compile and analyze data. Perform computations using image analysis software, spreadsheets, graphing, and curve fitting software
  • May modify protocols and be responsible for a single, independent research project
  • May assist with budget and/or operational aspects of grant and contract proposals
  • Assist in writing the text of scientific publications and grants.  Review literature
  • Train new laboratory personnel, students, and collaborators
  • Comply with all safety and infection control standards
  • Perform other duties as required.

                                                                                                           

 

Qualifications

REQUIRED QUALIFICATIONS:  

  • Bachelor’s degree in the Biological Sciences, or equivalent experience
  • 3 years of relevant research experience
  • Knowledge of Microsoft Office products
  • Strong ability to analyze complex visual data in a quantitative and objective manner
  • Judgment and action skills required to solve commonly encountered problems

SUPERVISION RECEIVED:

Under the direction of the Principal Investigator, or designee

 

SUPERVISION EXERCISED: 

May functionally supervise aides, technicians, and associates

 

ENVIRONMENTAL WORKING CONDITIONS:

Wet chemistry laboratory, and may require appropriate contact with biohazards, radionuclides, toxins, animals, and human specimens.

Additional Information

Lab information https://www.umassmed.edu/Wolfe-Lab/

 

Additional Information:

The focus of the Wolfe Laboratory is the development of genome editing (CRISPR/Cas systems) and gene regulation (zinc finger proteins) tools for the development of new classes of therapeutics. The successful candidate would be a part of an interdisciplinary team of laboratory scientists, clinicians, and computational biologists that are working on therapeutics for a variety of hematopoietic and neuromuscular disorders. We are looking for a candidate that would be a key player in purifying and characterizing novel genome editing proteins that would be used to develop therapies for these disorders.

 

Experience Desired (not required):

  • Protein purification (AKTA-based)
  • Basic molecular biology techniques (PCR, Restriction Enzyme mediated cloning, Gel electrophoresis, Qiagen DNA miniprep).   
  • Mammalian Cell culture experience.
  • Experience with bacterial selection systems.
  • Bacteria Strain preparation and handling (competent cell preparation and agar plate preparation). 
  • Major Responsibilities (in addition to the standard set):

  • Participate in the purification and characterization of various genome editing proteins.
  • Maintain bacterial and nucleic acid databases and archives
  • Organize ordering and stocking of supplies and reagents for laboratory.
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    Job No:
    Posted: 4/8/2021
    Application Due: 4/7/2022
    Work Type: Full Time
    Salary: