Postdoctoral Position in Infectious Diseases 2021-22-Kelesidis Research Group

Job description



Postdoctoral Position in Infectious Diseases 2021-22-Kelesidis Research Group
University of California Los Angeles



Requisition Number: JPF06307


The Division of Infectious Diseases, in the Department of Medicine, David Geffen School of Medicine at UCLA is seeking to applicants for a full-time, Postdoctoral position 2-year funded position by NIH. The incumbent will conduct research in novel therapeutic approaches to treat viral infections including HIV and Covid-19. Preferred qualifications: Familiar with techniques such as multi-color flow cytometry, sterile technique for cell culture with BSL-2+ practices, ELISA, qRT-PCR, immunofluorescence, Western Blot and molecular biology techniques. Mouse experience is preferred but is not required. Experience in virology research is preferred but is not required. The candidate should be comfortable working with BSL2+ biospecimens including biospecimens (cells, plasma, tissues) from patients or mice with COVID-19 and/or HIV. A Ph.D. is required.

Overview: The pandemic COVID-19 emphasized the need to develop novel therapeutic strategies to combat morbidity and mortality from viral infections. The Kelesidis laboratory focuses on novel antioxidants that target increased bioactive lipids and altered mitochondria to attenuate increased systemic inflammation, immune dysfunction and end organ disease in chronic HIV infection. Importantly these antioxidants were also recently shown to attenuate SARS-CoV-2 viral replication and associated inflammatory responses in lung cells. The lab uses in vitro cell culture models, ex vivo models of atherogenesis and gut explants to dissect mechanisms how the cross talk between bioactive lipids, immune, endothelial and epithelial cells drive atherogenesis and how novel therapeutic agents attenuate aberrant proinflammatory cellular pathways. The lab also uses a preclinical humanized mouse model of chronic treated HIV infection to study in vivo how novel therapies attenuate end organ disease. Recent areas of research include studies of pathogenesis of COVID-19 using preclinical in vitro and animal models of SARS-CoV-2 infection.

The University of California is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, age or protected veteran status. For the complete University of California nondiscrimination and affirmative action policy see: UC Nondiscrimination and Affirmative Action Policy.


To apply, please visit: https://recruit.apo.ucla.edu/JPF06307


The University of California is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, age or protected veteran status. For the complete University of California nondiscrimination and affirmative action policy, see: UC Nondiscrimination & Affirmative Action Policy, https://policy.ucop.edu/doc/4000376/DiscHarassAffirmAction


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Job No:
Posted: 4/7/2021
Application Due: 4/7/2033
Work Type: Full Time
Salary: