Professional Research Assistant - StemTech Lab Manager

Location
Boulder, Colorado
Posted
Apr 07, 2021
Employment Type
Full Time
Institution Type
Four-Year Institution
Requisition Number:

29637Location:

Boulder, Colorado Employment Type:

Research FacultySchedule:

Full-TimeDate Posted:

06-Apr-2021 Close All Job SummaryThe Lab Manager of the Stem Cell Research and Technology Resource Center at CU Boulder provides oversight of a shared facility that specializes in the use of human-induced pluripotent stem cells (hiPSC). This is a campus-wide facility that is also open to, and used by, external researchers beyond the CU Boulder campus. This position will be responsible for the daily operations of the Center, including training new users in all aspects of undifferentiated hiPSC culture, training users on fluorescence microscopy, evaluating and adopting new technologies and equipment, new project and service development, purchasing on a limited budget, performing product pricing and invoicing, and managing an online reservation system. This position requires excellent experimental skills and expertise in the growth of undifferentiated iPSCs, routine quality control testing required (e.g., karyotype analysis and mycoplasma testing), and knowledge of various reprogramming and differentiation methods. Experience with CRISPR/Cas9 genome-editing techniques and fluorescence microscopy is advantageous. This position is service-oriented and requires excellent interpersonal, communication, and customer service skills. Good planning and organizational skills are crucial.
The University of Colorado Boulder is committed to building a culturally diverse community of faculty, staff, and students dedicated to contributing to an inclusive campus environment. We are an Equal Opportunity employer, including veterans and individuals with disabilities. Who We Are

University of Colorado Boulder, Molecular, Cellular and Developmental Biology (MCDB) department.

Founded in 1968 by the pioneering cell biologist and electron microscopist, Keith Porter, MCDB was among the first departments to integrate molecular, cellular, and developmental biology. For nearly 50 years, MCDB researchers have made seminal contributions to our understanding of the structures of cells and organisms and the molecular underpinnings of life processes. A few of these early discoveries include: translational regulation of gene expression; bacterial motility by rotating flagella; fine structure of plant cell walls, tight junctions, chloroplasts, and mitotic spindles; temperature-sensitive and maternal effect mutations in C. elegans, and catalytic RNA.

Today, MCDB faculty and students continue this pursuit to understand life at its most fundamental levels. But we are also addressing many of the pressing biomedical problems facing society, such as cancer, heart disease, diabetes, blindness, neurological and muscle disorders, infectious disease and antibiotic resistance, and environmental destruction. Beyond making discoveries, MCDB continues its long tradition of excellence in cultivating and educating the next generations of research leaders, biomedical innovators, educators, and scientifically literate citizens.

What Your Key Responsibilities Will BeTraining
  • Discuss projects and assist new users in experimental design and implementation.
  • Train new users in basic sterile techniques and the undifferentiated growth of human iPSCs, including cryopreservation, thawing, passaging, troubleshooting, and best quality control practices. This may include undergraduate researchers and others with no prior mammalian cell culture experience.
  • Train and advise users in advanced iPSC techniques, including options for substrates, media, passaging, differentiation to target cell types, reprogramming, CRISPR/Cas9 genome-editing (including transfection), and 3D (organoid) culture.
  • Train users in Center equipment usage.
  • Periodically offer training workshops in human iPSC culture.

Lab Manager
  • Ensure all Center equipment is regularly maintained, cleaned, repaired, and serviced, including exchanging out compressed gas and liquid nitrogen tanks. Occasional weekend time may be required.
  • Keep inventory of Center supplies, order supplies based on past usage and changing user demand.
  • Organize supplies and general laboratory space to be customer-friendly and convenient, including maintaining an online reservation and invoicing system, and preparing user-friendly equipment instructions and other signage.
  • Prepare reagents and culture human iPSC lines to be available for users, ensuring quality control and a contamination-free environment.
  • Manage concerns and questions of users.
  • Perform cost analysis, maximized pricing, and tracking performance of reagents and services available to users to ensure cost-savings.
  • Develop and disseminate targeted communications showcasing resources available to current and potential users.
  • Interface with other Centers on campus and other iPSC resource centers for best practices and to make new resources available to users.
  • Work in coordination with users and EH&S to ensure compliance.
  • May manage one direct report who will primarily help maintaining the Center lab space.

Project Development
  • Adopt technologies that become standard in this fast-moving field. Remain abreast of literature in the field.
  • Develop new technologies in conjunction with other researchers, including engineers. CRISPR/Cas9 genome-editing experience preferred.
  • Work closely with faculty to prepare research grant proposals.
  • Commensurate with expertise and as time and interest allows, participate as collaborator on grant proposals for individual labs.
What You Should KnowWith a Masters or Ph.D. in relevant field, the overall duties could shift more towards Project Development putting more focus on the following:
  • Periodically offer training workshops in human iPSC culture, including developing lectures, videos, and advertisements.
  • Identify new equipment to make available at the Center depending upon funds available and user needs.
  • Manage a monthly stem cell seminar series (SCORE) advertised to more than 300 researchers.
  • Attend relevant conferences and/or workshops in the field to stay current with ideas, best practices, and new approaches (~1 time per year).
What We Can Offer$40,000 - $60,000 annually commensurate with experience, level of degree, and experience.BenefitsThe University of Colorado offers excellent benefits, including medical, dental, retirement, paid time off, tuition benefit and ECO Pass. The University of Colorado Boulder is one of the largest employers in Boulder County and offers an inspiring higher education environment. Learn more about the University of Colorado Boulder.Be StatementsBe Adaptable. Be Collaborative. Be Boulder.What We Require
  • Graduation from an accredited college or university with a Bachelor's degree or higher.
  • 5 years of research experience in a laboratory setting including 3-5 years of experience culturing human iPSCs and at least one differentiation technique.
What You Will Need
  • Possess excellent problem solving, written and oral communication skills.
  • Possess excellent organizational, customer service, and management skills.
What We Would Like You To Have
  • College degree in Science and 5+ years of experience in working in an academic laboratory or biotechnology company focused on human iPSC studies.
  • Experience in laboratory management and mentoring.
  • Knowledge of various iPSC differentiation protocols.
  • Familiarity with different iPSC culture conditions, including the advantages and shortcomings of each.
  • An understanding of different reprogramming methods and CRISPR/Cas9 genome-editing techniques with human iPSCs.
  • Experience in applying and designing biomaterials for three-dimensional growth of differentiated iPSCs.
Special Instructions

To apply, please submit the following materials:

  1. Resume/CV
  2. Cover Letter
  3. 1 Letter of Recommendation (Not Confidential)

Full consideration please apply by April 15th, 2021, and review will continue until the position is filled.

Note: Application materials will not be accepted via email. For consideration, applications must be submitted through CU Boulder Jobs.

Posting Contact InformationPosting Contact Name: Boulder Campus Human Resources

Posting Contact Email: [email protected]

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