Postdoctoral Research Associate
Job description
Position Title:
Postdoctoral Research Associate
Vacancy ID:PDS003040
Department:SOP-DPMP - 452400
Position Type:Postdoctoral Scholar
Salary Range:Dependent on experience and qualifications.
Full-time/Part-time:Full Time
FTE:1.0
Proposed Start Date:05/17/2021
Estimated Duration of Appointment:12 Months
Posting Open Date:04/01/2021
Open Until Filled:Yes
Work Location:Chapel Hill, NC
Position Summary:The Division of Pharmacoengineering and Molecular Pharmaceutics (DPMP) is engaged in research and education in drug delivery options to optimize the therapeutic efficacy of pharmacologically and immunologically active agents. It is a multidisciplinary endeavor requiring knowledge in pharmaceutics, chemistry, engineering, biochemistry, biologics, pharmacokinetics, drug metabolism, and biology.
Engineering antibodies for the development of cost-effective & potent therapeutics. Equipment usage will include thermocycler, gel apparatus, spectrophotometer, and computer-assisted software analysis (CASA), as well as nanoDSF, size exclusion chromatography multi-angle light scattering (SEC-MALS), and microscale thermophoresis (MST) from MacInFac core Perform procedures SDS-Page, ELISA, SEC-MALS and DSF to characterize all antibodies; Measure the potency of antibodies; Measure the complement-dependent cytotoxic activity using a bactericidal assay; Measure the neutralizing potency of antibodies using a luminescence-based assay; Coordinate the collection of human mucus samples for the lab.
Educational Requirements:PhD in Microbiology & Immunology.
Qualifications and Experience:Strong preferences will be given to those who have a strong background in (1) mucosal immunology/vaccines, (2) biophysical measurements, in particular multiple particle tracking and/or FRAP, and/or (3) microbiology, including work culturing commensal bacteria and performing 16s rRNA sequencing.
Equal Opportunity Employer:The University of North Carolina at Chapel Hill is an equal opportunity and affirmative action employer. All qualified applicants will receive consideration for employment without regard to age, color, disability, gender, gender expression, gender identity, genetic information, race, national origin, religion, sex, sexual orientation, or status as a protected veteran.
Special Instructions:Apply online at https://unc.peopleadmin.com/postings/190341 with a CV/resume and a list of least three professional references with their full contact information. A cover letter is optional but encouraged.
For information on UNC Postdoctoral Benefits and Services click here