Research Assistant 2

Job description

Job Title: Research Assistant 2
Location: Case Main Campus
Regular/Temporary: Regular
Full/Part Time: Full-Time
Job ID: 8756

Working under general supervision, plan and carry out research project in accordance with general plans. research projects involving standard molecular techniques (PCR, electrophoresis, RNA extraction), immunological techniques (ELISA, flow-cytometry, western blotting), animal handling, record-keeping of mouse breeding/genotyping, tissue processing (immunohistochemistry) and tissue-culturing/cell culture work. The Research Assistant will also collect, verify, record, compile and analyze data and information related to the ongoing research carried out in the lab. This position will oversee inventory and general lab maintenance. This position will work with animals.


    Plan and carry out project in accordance with general plans. Maintain animal breeding colonies of transgenic animals and coordinate tissue harvest. (42%)Conduct a series of experiments to supply scientific information as part of a larger project. Perform procedures and operate a variety of instruments and scientific equipment, i.e. microscopy, PCR, gel electrophoresis, histology, biochemical assays and others. perform tissue processing for histology (cryo- and paraffin-block sectioning) and histochemical staining, including immunohistochemistry and immunofluorescence. (20%)May assist in developing improved molecular biology and biochemistry techniques, projection methods or procedures in collecting animal tissue and isolating cells/DNA/RNA from blood and organs. (8%)Collect and analyze data. Perform data entry and maintain accurate records for genotyping in close coordination with the required lab personnel. Analyze samples and maintain cell/ tissue cultures for experimental purposes and analyzing animal tissues. (20%)


    Oversee inventory. Perform administrative duties such as ordering, stocking, organizing, and maintaining/ cleaning certain equipment facilities. (5%)Train new staff; direct the work of students in strict safety guidelines. (5%)Perform other duties as assigned. (<1%)


Department: Daily contact with supervisor and other laboratory personnel to discuss results and plans for maintaining colonies.

University: Occasional contact with other departments (i.e., Animal Resource Center) to share information.

External: Occasional contact with vendors to exchange information.

Students: Contact with student employees to provide training or instruction.


This position has no direct supervision of staff employees. Train new staff; direct the work of students.


Education and experience: bachelor's degree and 1 to 3 years of related experience or associate's degree in an approved biotechnology program and 2 to 4 years of experience.


    Previous experience in managing small animals and maintaining animal colonies is essential.Experience collecting animal tissue and isolating cells/DNA/RNA from blood and organs.Understanding of aseptic working practices. Ability to perform tissue processing for histology (cryo- and paraffin-block sectioning) and histochemical staining, including immunohistochemistry and immunofluorescence.Ability to perform basic molecular biology and biochemistry techniques. (PCR, molecular cloning, DNA and RNA isolation, RT-PCR, qPCR, ChIP, Western blotting, etc).Good organizational skills and record keeping.Ability to follow strict safety guidelines.Ability to meet consistent attendance. Ability to interact with colleagues, supervisors and customers face-to-face.Ability to follow through on assigned projects and provide timely follow-up.Ability to work in a fast-paced, changing environment, and conform to shifting priorities, demands, and timeline. Must be flexible in order to respond to project adjustments and alterations promptly and efficiently. Must be able to adapt to varying workloads and respond appropriately to stressful situations.Excellent verbal and written communication skills. Good interpersonal skills; ability to work and communicate professionally with various individuals within the laboratory and department.Must demonstrate compliance with CWRU animal research and care (ARC) policies and procedures and compliance to regulations of the Animal Welfare Act, Public Health Service Policy, AAALAC guidelines and other applicable regulatory guidelines.Must demonstrate compassion for animals within CWRU facilities and dedication to the Animal Resource Center’s mission. Must handle animals with care and respect at all times.

Typical laboratory environment. Personal laboratory safety devices will be provided. The employee will be exposed to animals and chemicals, UV light, fumes, dust.

Case's animal facilities are accredited by the Association for the Assessment and Accreditation of Laboratory Animal Care (AAALAC) and is managed according to the "Guide for the Care and Use of Laboratory Animals” appropriate Federal Animal Welfare Regulations, and the Public Health Service “Policy on the Humane Care and Use of Laboratory Animals." This position, and all animal research personnel, are subject to internal compliance to SOM Animal Resource Center Standard Operating Procedures and to compliance regulations of the Animal Welfare Act, Public Health Service Policy, AAALAC guidelines, the State of Ohio Veterinary Practice Act, Federal Drug Enforcement Administration regulatory guidelines, US Food and Drug Administration Center for Veterinary Medicine regulations and other applicable regulatory guidelines.

Diversity Statement

In employment, as in education, Case Western Reserve University is committed to Equal Opportunity and Diversity. Women, veterans, members of underrepresented minority groups, and individuals with disabilities are encouraged to apply.


Reasonable Accommodations

Case Western Reserve University provides reasonable accommodations to applicants with disabilities. Applicants requiring a reasonable accommodation for any part of the application and hiring process should contact the Office of Equity at 216-368-3066 to request a reasonable accommodation. Determinations as to granting reasonable accommodations for any applicant will be made on a case-by-case basis.





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Job No:
Posted: 4/1/2021
Application Due: 5/31/2021
Work Type: Full Time