University of Colorado – School of Medicine
Division of Renal Diseases and Hypertension
The University of Colorado Denver l Anschutz Medical Campus seeks individuals with demonstrated commitment to creating an inclusive learning and working environment. We value the ability to engage effectively with students, faculty and staff of diverse backgrounds.Overall Description of Responsibility or Nature of WorkThis position reports directly to Dr. Hopp in the Division of Renal Diseases and Hypertension and is responsible for understanding the importance of the cystic microenvironment in Polycystic Kidney Disease progression.This position supervises graduate students and PRAs in the Hopp laboratory. Areas of Responsibility / Scope of ResearchDr. Hopp’s laboratory studies Autosomal Dominant PKD (ADPKD) pathomechanisms. ADPKD is the most common monogenic renal disease worldwide with currently limited therapeutic options to alleviate disease burden characterized by progressive cyst growth and end stage renal disease. ADPKD has many molecular and cellular commonalities with cancer, in which the microenvironment has shown tremendous potential for therapeutic intervention. We are interested in studying the role of the microenvironment, specifically immune cells, in ADPKD progression and apply the knowledge gained from the cancer field to PKD. The project makes heavily use of PKD mouse models to understand the interplay between immune cells and cystic renal epithelial cells. Hence, a post-doctoral applicant should be familiar with utilizing mouse/rat models for basic/translational research including knowledge about mouse colony maintenance, genotyping, breeding of single, double, and triple transgenic lines, preclinical studies, and histopathological analyses. Additionally, background knowledge in immunology and immunological techniques (flow cytometry) are highly encouraged and experience with basic cellular, molecular techniques (Western blotting, PCR/qPCR, IHC/IF) and statistical analyses (Microsoft Excel/PRISM/JMP) are required. Salary and Benefits:The salary range for this position has been established at $53,760- $65,292, depending on corresponding NIH stipend level for years of experience. The salary of the finalist(s) selected for this role will be set based on a variety of factors, including but not limited to, internal equity, experience, education, specialty and training.The above salary range represents the University’s good faith and reasonable estimate of the range of possible compensation at the time of posting. The University of Colorado offers a full benefits package. Information on University benefits programs, including eligibility, is located at Employee Services. Postdoc-specific benefits are found here: https://www1.ucdenver.edu/offices/postdoc/postdocs/future-postdocsUniversity of Colorado Denver | Anschutz Medical Campus is dedicated to ensuring a safe and secure environment for our faculty, staff, students and visitors. To assist in achieving that goal, we conduct background checks for all new employees prior to their employment.The Immigration Reform and Control Act requires that verification of employment eligibility be documented for all new employees by the end of the third day of work. Alternative formats of this ad are available upon request for persons with disabilities.Your total compensation goes beyond the number on your paycheck. The University of Colorado provides generous leave, health plans and retirement contributions that add to your bottom line.Benefits: https://www.cu.edu/employee-services/benefits.Total Compensation Calculator: https://www.cu.edu/employee-services/total-compensationDiversity and Equity:Please click here for information on disability accommodations: http://www.ucdenver.edu/about/departments/HR/jobs/Pages/JobsatCUDenver.aspx The University of Colorado Denver | Anschutz Medical Campus is committed to recruiting and supporting a diverse student body, faculty and administrative staff. The university strives to promote a culture of inclusiveness, respect, communication and understanding. We encourage applications from women, ethnic minorities, persons with disabilities and all veterans. The University of Colorado is committed to diversity and equality in education and employment.
- Graduation from an accredited college or university with a PhD and or MD/PhD.
- Minimum of 4-year(s) experience in research, including the degree years
- Experience with mouse colony maintenance and preclinical trial execution
- Experience with basic cellular, molecular techniques (Western blotting, PCR/qPCR, IHC/IF) and statistical analyses (Microsoft Excel/PRISM/JMP).
- PhD in the field of renal, cilia, metabolism, or immunology research
- Proven experience and familiarity with the murine renal systems and procedures
- Proven ability to work independently within a research lab
- Experience in mentoring PhD students/laboratory technicians
- Excellent communication skills
- Demonstrated ability/proficiency/excellence computer software, equipment operation, or research technical skills
- Two or more first author publications origination from degree work
Job Category: Faculty
Primary Location: Aurora
Posting Date: Feb 26, 2021
Unposting Date: Ongoing