Product Development Scientific Manager

Job description

Job location: Smilow Center for Translational

Employment Type: Full-time
Posted data: 2021-02-12
Req: JR00029035
University Overview

The University of Pennsylvania, the largest private employer in Philadelphia, is a world-renowned leader in education, research, and innovation. This historic, Ivy League school consistently ranks among the top 10 universities in the annual U.S. News & World Report survey. Penn has 12 highly-regarded schools that provide opportunities for undergraduate, graduate and continuing education, all influenced by Penn’s distinctive interdisciplinary approach to scholarship and learning.

Penn offers a unique working environment within the city of Philadelphia. The University is situated on a beautiful urban campus, with easy access to a range of educational, cultural, and recreational activities. With its historical significance and landmarks, lively cultural offerings, and wide variety of atmospheres, Philadelphia is the perfect place to call home for work and play.

The University offers a competitive benefits package that includes excellent healthcare and tuition benefits for employees and their families, generous retirement benefits, a wide variety of professional development opportunities, supportive work and family benefits, a wealth of health and wellness programs and resources, and much more.

Posted Job Title

Product Development Scientific Manager

Job Profile Title

Manager Research Project B

Job Description Summary

The Product Development Laboratory (PDL) within the Center for Cellular Immunotherapies (CCI), seeks to hire a Research Project Manager B (working title: Product Development Scientific Manager) to oversee multiple product development and research projects related to improving gene/cell therapies. The Project Manager will supervise technical staff and report directly to the Director of the Product Development Laboratory (PDL). This person will be responsible for assisting in duties related to the oversight and conduct of the laboratory activities. Managerial and hands-on responsibilities comprise supervision of staff and student trainees as well as process development activities. These include review of data, trouble-shooting, instrument operation and advising the Directors on ways to improve operational efficiency while maintaining robustness, overseeing the proper training of staff, monitoring progress and timelines, contributing to manuscript and grant preparation as well as presentation, addressing interim problems as they arise and management of technology transfer from the development to the implementation teams. This individual will assist the Director of PDL in strategic development and plans leading to the discovery and clinical translation of new cellular manufacturing processes. Additional administrative responsibilities include reviewing and signing-off on product/process validation reports, managing and tracking multiple study budgets as well as compiling IND data packages and the timely submission of these documents to the Directors. The Product Development Scientific Manager will meet regularly with team members to ensure the proper and timely execution of projects, and with study leadership to provide updates, but will function independently in carrying out most responsibilities involving the support of early phase cell and gene therapy clinical trials at the University of Pennsylvania and collaborating institutions. In addition, this person will be expected to participate in collaborations involving cutting-edge cellular manufacturing process/product improvements. Maintaining an understanding of emerging concepts is required. This individual will also perform hands-on laboratory experiments related to cellular product development as needed. Finally, the Product Development Scientific Manager will undertake cross-functional engagement with multiple functional units within CCI, including, but not limited to the Clinical Cell and Vaccine Production Facility and Translational Science Operations for advancing new processes/ cell therapy products to the clinic.

Job Description

Responsible for both strategic planning and day to day management of complex and broad range of projects conducted with collaborators both internal and external to Penn. With mentoring from the Principal Investigator, the Research Project Manager will take leadership role in developing study protocols, writing grants, managing the detailed operations of projects, analyzing qualitative and quantitative data, cultivating close relationships with community partner organizations, and drafting/editing manuscripts for submission to peer-reviewed journal. He/she will help develop the team's research strategy and will have ample opportunities to lead projects and co-author papers. Will be required to ensure that studies/research are conducted safely and according to protocol, provide supervision to educators and teams conducting the study/interventions and collaborates with peers from other Universities and funding agencies. Will also be responsible for coordinating grant applications and interacts with funding administrators and the University Business Office. Provides significant contributions to presentations and manuscripts, including multiple drafts for review and dissemination. Plays a primary role in other dissemination activities related to project findings.

Position contingent upon funding.

Qualifications Requirements:
• Masters degree and 3-5+ years of relevant experience in immunology and/or cancer research or an equivalent combination of education and experience

• Ph.D. in immunology or related discipline preferred
• Prior experience in academia and required;
• Experience in handling and working with animal models required;
• Experience in mentoring and training;
• Strong communication skills (verbal and written);
• Strong background and publication record in the areas of human T cell immunology and leukemia biology;
• Highly functioning, detail-oriented, and analytical candidate who can think strategically and holistically about technology and product development, and collaborative efforts across laboratories with CCI;
• Strong experience working on research teams and directly participating in research studies;
• Strong multitasking abilities and an extremely high-level of reliability and dependability;
• Strong interpersonal skills. are essential;
• Self-starter with a strong desire to contribute and work collaboratively to achieve goals;
• Ability to develop and maintain multiple internal and external relationships regarding research;
• Must have strong experience working with flow cytometry equipment such as BD LSRFortessa, BD LSRII, BD FACSAria;
• Must have experience using software for data analysis such as BD FACSDiva, PRISM, FlowJo, and Microsoft Excel.
• Preferred:
Understanding of manufacturing and product development as it relates to gene and cell therapy. Prior experience working in large, complex organizations such as the University of Pennsylvania. Prior experience with managing complicated research projects with multiple sub-teams of researchers.
Working Conditions
Office, library, computer room

Physical Effort
Typically sitting at a desk or table; Occasional lifting 25 lb. or less; Typically standing or walking

Job Location - City, State

Philadelphia, Pennsylvania

Department / School

Perelman School of Medicine

Pay Range

$59,703.00 - $113,435.00

Affirmative Action Statement 
Penn adheres to a policy that prohibits discrimination on the basis of race, color, sex, sexual orientation, gender identity, religion, creed, national or ethnic origin, citizenship status, age, disability, veteran status, or any other legally protected class.

Special Requirements 
Background check required after a conditional job offer is made. Consideration of the background check will be tailored to the requirements of the job.




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Job No:
Posted: 2/13/2021
Application Due: 5/14/2021
Work Type: Full Time