Research Assistant 3

Job description

Job Title: Research Assistant 3
Location: Case Main Campus
Regular/Temporary: Regular
Full/Part Time: Full-Time
Job ID: 8686
Job Description


Working under limited supervision and working closely with the principal investigator, the Research Assistant 3 will be responsible for coordinating the efforts of the lab when it comes to applying novel machine learning and deep learning tools in digital pathology of diseases towards detection, diagnosis, prognosis as well as treatment response. The Research Assistant 3 will serve as the clinical lead in the digital pathology projects ongoing in Center for Computational Imaging and Personalized Diagnostics. Duties include providing expert annotations, segmentations, identifications of primitives and regions of interest, providing input in hand-crafted feature learning approaches, quality control of slides as well as algorithm validation and development. The Research Assistant 3 will also be responsible for being the point person regarding all of the digital pathology projects including slide scanning, clinical data management and database upkeep.


    Select diagnostic pathology tissue slides, which would be suitable for artificial-intelligence analysis from the tissue block. Quality control the slides for artificial-intelligence analysis by identifying artifacts, stain variations and slide preparation strategies. (12%)Scan whole mounts and slides using a whole slide scanner. (12%)Annotate biological primitives of interest on the digitized images for artificial-intelligence analysis. (12%)Segment regions of interest i.e. Cancer, disease, inflammation on digitized tissue images for artificial-intelligence analysis. (12%)Validate AI strategies in detecting primitives or segmenting regions of interest by evaluating their accuracy. (12%)Work closely with PhDs and research associates in the lab for efficient tool development and validation and provide clinical input in developing novel hand-crafted feature strategies. (10%)Write manuscripts based on the research projects. May co-author research projects. (10%)Maintain a database and archive of the slides being scanned for different projects along with their relevant clinical information. (9%)Participate in strategy and planning meetings with the center director/principal investigator and the research team to ascertain needs and actions associated with the research projects and the associated research goals. Must have an understanding of the domain of the research and be acutely aware of the research projects and the research goals. (9%)


Perform other duties as assigned. (2%)


Department: Daily interaction with the director, research faculty, and other team members to discuss research projects and maintain the workflow.

University: Occasional to frequent interaction with other departments to share information and collaborate on research projects.

External: Occasional to frequent contact with collaborators at University Hospitals, Cleveland Clinic, and with collaborators at collaborating institutions.

Students: Contact with undergraduate and graduate students within the Center


Mentor graduate and undergraduate students in the lab especially in the field of clinical pathology.


Experience: 3 to 5 years of related experience required.

Education/Licensing: Bachelor’s degree in science. Prefer graduate level experience in pathology or a MD degree.


    Extensive expert level domain knowledge in pathology.Expert knowledge in ImageScope, QuPath for viewing and analyzing pathology images.Familiarity with whole slide digital scanners and scanning protocols.Professional and effective oral and written communications skills. Must be able to clearly relay information to the Center Director and other researchers and prepare reports as needed. Effective management skills; ability to lead, train, work with, and elicit cooperation from team members and staff. Ability to problem solve effectively; ability to develop and implement alternative solutions as needed.Ability to learn and apply new ideas, techniques, processes, policies, functions, etc. Must be highly motivated and a self-starter.A willingness to acquire further skills and to train research team members (including students) on these skills.Ability to meet consistent attendance. Ability to interact with colleagues, supervisors, and customers face to face.


The working conditions are typical of an office environment and computer rooms. There will be little to no exposure to hazards. The work requires negligible physical exertion, however, limited manual dexterity is required.

Diversity Statement

In employment, as in education, Case Western Reserve University is committed to Equal Opportunity and Diversity. Women, veterans, members of underrepresented minority groups, and individuals with disabilities are encouraged to apply.


Reasonable Accommodations

Case Western Reserve University provides reasonable accommodations to applicants with disabilities. Applicants requiring a reasonable accommodation for any part of the application and hiring process should contact the Office of Equity at 216-368-3066 to request a reasonable accommodation. Determinations as to granting reasonable accommodations for any applicant will be made on a case-by-case basis.





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Job No:
Posted: 2/12/2021
Application Due: 5/13/2021
Work Type: Full Time