Senior Research Investigator
- Employer
- University of Pennsylvania
- Location
- Smilow Center for Translational
View more
- Administrative Jobs
- Academic Affairs, Research Staff & Technicians
- Employment Type
- Full Time
- Institution Type
- Four-Year Institution
Job Details
Job location: Smilow Center for Translational
Employment Type: Full-time
Posted data: 2021-01-12
Req: JR00027721
University OverviewThe University of Pennsylvania, the largest private employer in Philadelphia, is a world-renowned leader in education, research, and innovation. This historic, Ivy League school consistently ranks among the top 10 universities in the annual U.S. News & World Report survey. Penn has 12 highly-regarded schools that provide opportunities for undergraduate, graduate and continuing education, all influenced by Penn’s distinctive interdisciplinary approach to scholarship and learning.Penn offers a unique working environment within the city of Philadelphia. The University is situated on a beautiful urban campus, with easy access to a range of educational, cultural, and recreational activities. With its historical significance and landmarks, lively cultural offerings, and wide variety of atmospheres, Philadelphia is the perfect place to call home for work and play.The University offers a competitive benefits package that includes excellent healthcare and tuition benefits for employees and their families, generous retirement benefits, a wide variety of professional development opportunities, supportive work and family benefits, a wealth of health and wellness programs and resources, and much more.Posted Job TitleSenior Research InvestigatorJob Profile TitleResearch Investigator, SeniorJob Description SummaryThe Senior Research Investigator will devote his/her time conducting research on the area of the role of the UPR/ISR in tumor progression and metastasis. She/he will perform experiments aimed at delineating the role of the transcription factor ATf4 in establishing the premetastatic niche and the role of ATF4 downstream effectors (collagen, ASNS etc) in this process. Employee will work with the PI, research specialists, as well as graduate and undergraduate students to coordinate and execute experiments in these areas including reviewing their experimental data and suggesting future experiments. A significant percentage of his/her time will be devoted to help the PI create grant proposals involving the areas listed above as well as prepare his/her own applications for intramural and extramural funding.Job Description
The Senior Research Investigator will devote his/her time conducting research in the areas of study of the tumor microenvironment and development and testing of new radiation response modifiers. This position requires the employee to be able to work with a great deal of independence in devising new areas of investigation and designing experiments.The investigator will work on delineating the role of the Unfolded Protein Response and Integrated Stress Response (UPR/ISR) in the tumor stroma (fibroblasts, immune cells, and endothelial cells) in promoting tumor growth.She/he will also engage in developing new models of proton radiation damage using different mouse strains and analyze the combined effects of radiation and UPR/ISR modifiers in the response of normal tissue to radiotherapy.Much of this work will be conducted in tumors grown in mice.Employee will work with the PI, research associates and students to coordinate and execute experiments in these areas including reviewing their experimental data and suggesting future experiments.A significant percentage of his/her time will be devoted to help the PI create grant proposals and also submit grant proposals on their own.
Qualifications
Highly advanced professional discipline. M.D., Ph.D., or equivalent doctoral degree and 5-7 years of experience is required.
Position contingent upon funding.
Working Conditions
Office, library, computer room; Requires extensive safety training; Exposure to chemicals; Requires protective devices
Physical Effort
Typically sitting at a desk or table; Typically standing or walking; Intermittently sitting/standing/stooping
Penn adheres to a policy that prohibits discrimination on the basis of race, color, sex, sexual orientation, gender identity, religion, creed, national or ethnic origin, citizenship status, age, disability, veteran status, or any other legally protected class.Special Requirements
Background check required after a conditional job offer is made. Consideration of the background check will be tailored to the requirements of the job.
Organization
Welcome to the University of Pennsylvania! Penn is the largest private employer in Philadelphia and is a world-renowned leader in education, research, and innovation.
Across our 12 highly-regarded schools, more than 25,000 students, and more than 4,000 faculty members, we become one university: a wide-ranging, ever-changing community that draws its strength from a multitude of races, ethnicities, genders, sexual orientations, historical traditions, ages, religions, disabilities, veteran status, interests, perspectives, and socioeconomic backgrounds.
Penn carries on the principles and spirit of its founder, Benjamin Franklin: entrepreneurship, innovation, invention, outreach, and a pragmatic love of knowledge. Franklin's practical outlook has remained a driving force in the university's development. To learn more, visit About Penn.
Vision
As engines of knowledge and new ideas, universities have the unique potential to define the future rather than be defined by it; to pioneer change rather than merely manage it. To do so requires a plan both visionary and pragmatic. The Penn Compact 2022 motivates community members to innovate, be radically inclusive, and positively impact their local, national, and global communities.
Penn’s fundamental priorities — increasing access, integrating knowledge and engaging locally, nationally and globally — are supported by the three core values that make us uniquely Penn: inclusion, innovation, and impact.
Learn about the signature initiatives of the Penn Compact 2022:
- Global Connections President’s Engagement Prizes President's Innovation Prize Penn Integrates Knowledge University Professors
Diversity
Understanding and appreciating diversity is one of Penn's most important priorities and is fundamental to success in today's world.
Penn adheres to a policy that prohibits discrimination on the basis of race, color, sex, sexual orientation, gender identity, religion, creed, national or ethnic origin, citizenship status, age, disability, veteran status, or any other legally protected class.
To learn more about Diversity and Inclusion at Penn visit:
- Diversity at Penn Resources Supporting Diversity Penn Diversity Facts and Figures Penn's Diversity Timeline 1740-1997
Benefits
Penn offers a wide range of benefits and perks - from Penn's retirement Matching Plan to bike repair stations to access to the full LinkedIn Learning library to adoption assistance to workshops at the letterpress and book arts studio and much more!
- Penn HR Benefits Be in the Know Wellness Campaign Penn Home Ownership Services Campus Shuttles & Buses Resources for Cyclists Deals@Penn Common Press
Campus and Beyond
We invite you to explore our campus and its stately buildings and state-of-the-art facilities.
- Penn Park Morris Arboretum Penn Campus Arboretum: 6,800 Campus Trees Penn Recreation Penn Libraries Shop Penn
Try our self-guided tour! Come and visit!
Learn about sustainability at Penn.
News
Stay up-to-date with Penn's response to COVID-19: Coronavirus Information & Resources.
Penn supports news publications that tell the ongoing story of the University community, communications services for external media, telephone and video services, and other media resources: Campus Media
Connect with us!
- Telephone
- (215) 898-7372
- Location
-
3451 Walnut Street
Philadelphia
PA
19104
US
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