Laboratory Specialist in Pharmacology (Sharlow Lab)

Job description

Job location: Charlottesville, VA

Employment Type: Full-time
Posted data: 2021-01-11
Req: R0020551

The Department of Pharmacology is seeking a Laboratory Specialist to assist investigators with in vitro and cell-based assay systems focusing on cultured adult human neurons (iNeurons) derived from adult fibroblasts, and the reengagement of cell cycle associated proteins and other signaling effectors. This position is within the laboratory of Dr. Elizabeth R. Sharlow. The individual will provide research support for ongoing research projects related to the derivation, development and refinement of neuronal populations and their use in novel assay systems. Experience with RT-PCR, drug/peptide handling, mammalian cell culture and/or sterile technique and/or additional molecular biology experience is required. A Bachelor’s degree in biology, chemistry, biochemistry, molecular biology or a related discipline and at least 3 years of laboratory experience in an academic or industrial laboratory setting is required; six or more years of experience may be accepted in lieu of a degree. Familiarity with laboratory equipment (i.e., centrifuges, pH meters, pipettors), and the ability to perform calculations and carry out experiments is required. Experience with Microsoft Office (i.e., Word, Powerpoint and Excel) is also required. Experience with GraphPad Prism is preferred.

What you will do:

Experimental Work:

  • Implement experiments using iNeurons.
  • Help derive iNeuron populations.
  • Use sterile technique and perform EC50/IC50 determinations.
  • Perform mammalian cell culture.
  • Perform Western blotting and use antibodies.
  • Perform data analysis and visualization.
  • Perform immunofluorescence.
  • Present data at laboratory meetings.

Laboratory Maintenance and General Duties:

  • Maintain a clean laboratory area and assist with overall laboratory maintenance
  • Make buffers and other reagents
  • Maintain a laboratory notebook
  • Be available to assist principal investigators as needed

Ordering, Purchasing, and Shipping:

  • Process purchases for the lab
  • Interact with vendors to determine appropriate products
  • Return damaged or incorrect items
  • Ship items to contract research organizations

** This is a restricted position and continuation will be based on availability of funding and satisfactory performance. **

Anticipated Hiring Range: $35,000 - $38,000

The selected applicant will be required to complete a background check prior to their first day of employment per University policy.


PROCESS FOR INTERNAL UVA APPLICANTS: Please apply through your Workday Home page, search “Find Jobs”, and search for “R0020551". Complete an application online and see below for documents to attach.

PROCESS FOR EXTERNAL APPLICANTS: Please visit UVA job board, “R0020551” complete the application and see below for documents to attach. Please note that multiple documents can be uploaded in the box or you can combine them into one PDF.

Complete an application online and attach:


·Cover Letter

·Contact information for 3 references

***Please note that you MUST upload ALL documents into the CV/Resume box.

Applications that do not contain all of the required documents will not receive full consideration.***

For questions about the application process please contact Rhiannon O'Coin, Senior Academic Recruiter,

This position can spend extensive periods of time standing and squatting while conducting experiments or caring for animals. Also requires keyboarding and other bench work and animal procedures requiring finer finger manipulation.

The University of Virginia, including the UVA Health System which represents the UVA Medical Center, Schools of Medicine and Nursing, UVA Physician’s Group and the Claude Moore Health Sciences Library, are fundamentally committed to the diversity of our faculty and staff. We believe diversity is excellence expressing itself through every person's perspectives and lived experiences. We are equal opportunity and affirmative action employers. All qualified applicants will receive consideration for employment without regard to age, color, disability, gender identity or expression, marital status, national or ethnic origin, political affiliation, race, religion, sex (including pregnancy), sexual orientation, veteran status, and family medical or genetic information.




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Job No:
Posted: 1/13/2021
Application Due: 4/13/2021
Work Type: Full Time