Research Instructor

Job description

Position Type:

Permanent Faculty

Working Title:

Research Instructor

Appointment Type:

Fixed Term Faculty

Salary Range:

Dependent on Qualifications and Experience


Full-Time Permanent

Vacancy ID:


Posting Open Date:


Application Deadline:


Open Until Filled:


Proposed Start Date:


Position Summary:

The Dotti lab seeks a Research Instructor to conduct experiments in uncovering the role of the tumor microenvironment in hampering the effects of CAR-T cells. Specifically, work will implement tumor models in immunocompetent mice and test measures to improve the antitumor effects of 3rd generation CAR-T cells. Specifically tumor bearing mice will be lymphodepleted and treated with conventional CAR-T cells versus CAR-T cells further modified to counter tumor-associate escape mechanism. The project would require significant skills in mouse modelling and CAR-T cells related techniques. Multiple assays will be applied to study the function of CAR-T cells and their molecular and signaling characterization. The position also involves mentoring technical staff and postdocs and a minor role in lab management.

Educational Requirements:

PhD in Cell Biology or related field

Qualifications and Experience:

The ideal candidate will have at least two years of experience in mouse modelling and CAR-T cell technology.

Equal Opportunity Employer:

The University of North Carolina at Chapel Hill is an equal opportunity and affirmative action employer. All qualified applicants will receive consideration for employment without regard to age, color, disability, gender, gender expression, gender identity, genetic information, national origin, race, religion, sex, sexual orientation, or status as a protected veteran.




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Job No:
Posted: 1/5/2021
Application Due: 4/5/2021
Work Type: Full Time